10,074 research outputs found

    U.S. EEOC v. Big Lots, Inc., et al.

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    EEOC v. Aqua Tri Pool Water Products,

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    U.S. EEOC v. Aqua Tri, et al.

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    Qualitative System Identification from Imperfect Data

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    Experience in the physical sciences suggests that the only realistic means of understanding complex systems is through the use of mathematical models. Typically, this has come to mean the identification of quantitative models expressed as differential equations. Quantitative modelling works best when the structure of the model (i.e., the form of the equations) is known; and the primary concern is one of estimating the values of the parameters in the model. For complex biological systems, the model-structure is rarely known and the modeler has to deal with both model-identification and parameter-estimation. In this paper we are concerned with providing automated assistance to the first of these problems. Specifically, we examine the identification by machine of the structural relationships between experimentally observed variables. These relationship will be expressed in the form of qualitative abstractions of a quantitative model. Such qualitative models may not only provide clues to the precise quantitative model, but also assist in understanding the essence of that model. Our position in this paper is that background knowledge incorporating system modelling principles can be used to constrain effectively the set of good qualitative models. Utilising the model-identification framework provided by Inductive Logic Programming (ILP) we present empirical support for this position using a series of increasingly complex artificial datasets. The results are obtained with qualitative and quantitative data subject to varying amounts of noise and different degrees of sparsity. The results also point to the presence of a set of qualitative states, which we term kernel subsets, that may be necessary for a qualitative model-learner to learn correct models. We demonstrate scalability of the method to biological system modelling by identification of the glycolysis metabolic pathway from data

    Non-universal Zβ€²Z' from Fluxed GUTs

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    We make a first systematic study of non-universal TeV scale neutral gauge bosons Zβ€²Z' arising naturally from a class of F-theory inspired models broken via SU(5)SU(5) by flux. The phenomenological models we consider may originate from semi-local F-theory GUTs arising from a single E8E_8 point of local enhancement, assuming the minimal Z2{\cal Z}_2 monodromy in order to allow for a renormalisable top quark Yukawa coupling. We classify such non-universal anomaly-free U(1)β€²U(1)' models requiring a minimal low energy spectrum and also allowing for a vector-like family. We discuss to what extent such models can account for the anomalous BB-decay ratios RKR_{K} and RKβˆ—R_{K^*}.Comment: 14 page

    Gauge Coupling Unification in E6 F-Theory GUTs with Matter and Bulk Exotics from Flux Breaking

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    We consider gauge coupling unification in E6 F-Theory Grand Unified Theories (GUTs) where E6 is broken to the Standard Model (SM) gauge group using fluxes. In such models there are two types of exotics that can affect gauge coupling unification, namely matter exotics from the matter curves in the 27 dimensional representation of E6 and the bulk exotics from the adjoint 78 dimensional representation of E6. We explore the conditions required for either the complete or partial removal of bulk exotics from the low energy spectrum. In the latter case we shall show that (miraculously) gauge coupling unification may be possible even if there are bulk exotics at the TeV scale. Indeed in some cases it is necessary for bulk exotics to survive to the TeV scale in order to cancel the effects coming from other TeV scale matter exotics which would by themselves spoil gauge coupling unification. The combination of matter and bulk exotics in these cases can lead to precise gauge coupling unification which would not be possible with either type of exotics considered by themselves. The combination of matter and bulk exotics at the TeV scale represents a unique and striking signature of E6 F-theory GUTs that can be tested at the LHC.Comment: 21 pages, 5 figure

    Workplace screening programs for chronic disease prevention: a rapid review

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    This review examined the effectiveness of workplace screening programs for chronic disease prevention based on evidence retrieved from the main databases of biomedical and health economic literature published to March 2012, supplemented with relevant reports. The review found: 1. Strong evidence of effectiveness of HRAs (when used in combination with other interventions) in relation to tobacco use, alcohol use, dietary fat intake, blood pressure and cholesterol 2. Sufficient evidence for effectiveness of worksite programs to control overweight and obesity 3. Sufficient evidence of effectiveness for workplace HRAs in combination with additional interventions to have favourable impact on the use of healthcare services (such as reductions in emergency department visits, outpatient visits, and inpatient hospital days over the longer term) 4. Sufficient evidence for effectiveness of benefits-linked financial incentives in increasing HRA and program participation 5. Sufficient evidence that for every dollar invested in these programs an annual gain of 3.20(range3.20 (range 1.40 to $4.60) can be achieved 6. Promising evidence that even higher returns on investment can be achieved in programs incorporating newer technologies such as telephone coaching of high risk individuals and benefits-linked financial incentive
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