2,604 research outputs found
Stability and BPS branes
We define the concept of Pi-stability, a generalization of mu-stability of
vector bundles, and argue that it characterizes N=1 supersymmetric brane
configurations and BPS states in very general string theory compactifications
with N=2 supersymmetry in four dimensions.Comment: harvmac, 18 p
Computing exponentially faster: Implementing a nondeterministic universal Turing machine using DNA
The theory of computer science is based around Universal Turing Machines
(UTMs): abstract machines able to execute all possible algorithms. Modern
digital computers are physical embodiments of UTMs. The nondeterministic
polynomial (NP) time complexity class of problems is the most significant in
computer science, and an efficient (i.e. polynomial P) way to solve such
problems would be of profound economic and social importance. By definition
nondeterministic UTMs (NUTMs) solve NP complete problems in P time. However,
NUTMs have previously been believed to be physically impossible to construct.
Thue string rewriting systems are computationally equivalent to UTMs, and are
naturally nondeterministic. Here we describe the physical design for a NUTM
that implements a universal Thue system. The design exploits the ability of DNA
to replicate to execute an exponential number of computational paths in P time.
Each Thue rewriting step is embodied in a DNA edit implemented using a novel
combination of polymerase chain reactions and site-directed mutagenesis. We
demonstrate that this design works using both computational modelling and in
vitro molecular biology experimentation. The current design has limitations,
such as restricted error-correction. However, it opens up the prospect of
engineering NUTM based computers able to outperform all standard computers on
important practical problems
The spectrum of BPS branes on a noncompact Calabi-Yau
We begin the study of the spectrum of BPS branes and its variation on lines
of marginal stability on O_P^2(-3), a Calabi-Yau ALE space asymptotic to
C^3/Z_3. We show how to get the complete spectrum near the large volume limit
and near the orbifold point, and find a striking similarity between the
descriptions of holomorphic bundles and BPS branes in these two limits. We use
these results to develop a general picture of the spectrum. We also suggest a
generalization of some of the ideas to the quintic Calabi-Yau.Comment: harvmac, 45 pp. (v2: added references
A Spectroscopic Study of Mass Outflows in the Interacting Binary RY Scuti
The massive interacting binary RY Scuti is an important representative of an
active mass-transferring system that is changing before our eyes and which may
be an example of the formation of a Wolf-Rayet star through tidal stripping.
Utilizing new and previously published spectra, we present examples of how a
number of illustrative absorption and emission features vary during the binary
orbit. We identify spectral features associated with each component, calculate
a new, double-lined spectroscopic binary orbit, and find masses of 7.1 +/- 1.2
M_sun for the bright supergiant and 30.0 +/- 2.1 M_sun for the hidden massive
companion. Through tomographic reconstruction of the component spectra from the
composite spectra, we confirm the O9.7 Ibpe spectral class of the bright
supergiant and discover a B0.5 I spectrum associated with the hidden massive
companion; however, we suggest that the latter is actually the spectrum of the
photosphere of the accretion torus immediately surrounding the massive
companion. We describe the complex nature of the mass loss flows from the
system in the context of recent hydrodynamical models for beta Lyr, leading us
to conclude RY Scuti has matter leaving the system in two ways: 1) a bipolar
outflow from winds generated by the hidden massive companion, and 2) mass from
the bright O9.7 Ibpe supergiant flowing from the region near the L2 point to
fill out a large, dense circumbinary disk. This circumbinary disk (radius ~ 1
AU) may feed the surrounding double-toroidal nebula (radius ~ 2000 AU).Comment: 41 pages with 7 tables and 11 figures, accepted to Ap
Fusion of multispectral imagery and spectrometer data in UAV remote sensing
High spatial resolution hyperspectral data often used in precision farming applications are not available from current satellite sensors, and difficult or expensive to acquire from standard aircraft. Alternatively, in precision farming, unmanned aerial vehicles (UAVs) are emerging as lower cost and more flexible means to acquire very high resolution imagery. Miniaturized hyperspectral sensors have been developed for UAVs, but th
Multiple universes, cosmic coincidences, and other dark matters
Even when completely and consistently formulated, a fundamental theory of
physics and cosmological boundary conditions may not give unambiguous and
unique predictions for the universe we observe; indeed inflation, string/M
theory, and quantum cosmology all arguably suggest that we can observe only one
member of an ensemble with diverse properties. How, then, can such theories be
tested? It has been variously asserted that in a future measurement we should
observe the a priori most probable set of predicted properties (the
``bottom-up'' approach), or the most probable set compatible with all current
observations (the ``top-down'' approach), or the most probable set consistent
with the existence of observers (the ``anthropic'' approach). These inhabit a
spectrum of levels of conditionalization and can lead to qualitatively
different predictions. For example, in a context in which the densities of
various species of dark matter vary among members of an ensemble of otherwise
similar regions, from the top-down or anthropic viewpoints -- but not the
bottom-up -- it would be natural for us to observe multiple types of dark
matter with similar contributions to the observed dark matter density. In the
anthropic approach it is also possible in principle to strengthen this argument
and the limit the number of likely dark matter sub-components. In both cases
the argument may be extendible to dark energy or primordial density
perturbations. This implies that the anthropic approach to cosmology,
introduced in part to explain "coincidences" between unrelated constituents of
our universe, predicts that more, as-yet-unobserved coincidences should come to
light.Comment: 18 JCAP-style pages, accepted by JCAP. Revised version adds
references and some clarification
Stent placement compared with balloon angioplasty for obstructed coronary bypass grafts. Saphenous Vein De Novo Trial Investigators.
BACKGROUND: Treatment of stenosis in saphenous-vein grafts after coronary-artery bypass surgery is a difficult challenge. The purpose of this study was to compare the effects of stent placement with those of balloon angioplasty on clinical and angiographic outcomes in patients with obstructive disease of saphenous-vein grafts.
METHODS: A total of 220 patients with new lesions in aortocoronary-venous bypass grafts were randomly assigned to placement of Palmaz-Schatz stents or standard balloon angioplasty. Coronary angiography was performed during the index procedure and six months later.
RESULTS: As compared with the patients assigned to angioplasty, those assigned to stenting had a higher rate of procedural efficacy, defined as a reduction in stenosis to less than 50 percent of the vessel diameter without a major cardiac complication (92 percent vs. 69 percent, P\u3c0.001), but they had more frequent hemorrhagic complications (17 percent vs. 5 percent, P\u3c0.01). Patients in the stent group had a larger mean (+/-SD) increase in luminal diameter immediately after the procedure (1.92+/-0.30 mm, as compared with 1.21+/-0.37 mm in the angioplasty group; P\u3c0.001) and a greater mean net gain in luminal diameter at six months (0.85+/-0.96 vs. 0.54+/-0.91 mm, P=0.002). Restenosis occurred in 37 percent of the patients in the stent group and in 46 percent of the patients in the angioplasty group (P=0.24). The outcome in terms of freedom from death, myocardial infarction, repeated bypass surgery, or revascularization of the target lesion was significantly better in the stent group (73 percent vs. 58 percent, P = 0.03).
CONCLUSIONS: As compared with balloon angioplasty, stenting of selected venous bypass-graft lesions resulted in superior procedural outcomes, a larger gain in luminal diameter, and a reduction in major cardiac events. However, there was no significant benefit in the rate of angiographic restenosis, which was the primary end point of the study
2020-04-06 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING
Executive Summary:
NM case updates. Several NM policy and legislative actions. Federal vs. state conflict over medical supply lines. Healthcare workers sleep in cars to prevent family exposure. Same-day in-house testing at Cedars-Sinai. Debate over hydroxychloroquine Tx. Death rate differences: Germany and Italy. African innovations. Testing recommended with mild symptoms. CDC guidelines for law enforcement PPE. New WHO first responder training and CDC sign language resources. COVID-19 droplets can travel up to 27 feet. Transmission from the asymptomatic. Humidifiers help. Drug and vaccine progress
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