Physiological monitoring in the complex multimorbid heart failure patient - Conclusions.

Comorbidities are increasingly recognized as crucial components of the heart failure syndrome. Main specific challenges are polypharmacy, poor adherence to treatments, psychological aspects, and the need of monitoring after discharge. The chronic multimorbid patient therefore represents a specific heart failure phenotype that needs an appropriate and continuous management over time. This supplement issue covers the key points of a series of meeting coordinated by the Heart Failure Association of the European Society of Cardiology (ESC), that have discussed the issues surrounding the effective monitoring of our ever more complex and multimorbid heart failure patients. Here, we present an overview of the complex issues from a healthcare delivery perspective

Shot noise free conductance reduction in quantum wires

We show that a shot noise free current at conductance below 2 e^2/h is possible in short interacting quantum wires without spin-polarization. Our calculation is done for two exactly solvable limits of the ``Coulomb Tonks gas'', a one-dimensional gas of impenetrable electrons that can be realized in ultra-thin quantum wires. In both cases we find that charge transport through such a wire is noiseless at zero temperature while the conductance is reduced to e^2/h.Comment: 4 pages, 1 figur

Frequency-dependent transport through a quantum dot in the Kondo regime

We study the AC conductance and equilibrium current fluctuations of a Coulomb blockaded quantum dot. A relation between the equilibrium spectral function and the linear AC conductance is derived which is valid for frequencies well below the charging energy of the quantum dot. Frequency-dependent transport measurements can thus give experimental access to the Kondo peak in the equilibrium spectral function of a quantum dot. We illustrate this in detail for typical experimental parameters using the numerical renormalization group method in combination with the Kubo formalism.Comment: 4 pages, 4 figure

Phase Transitions in liquid Helium 3

The phase transitions of liquid Helium 3 are described by truncations of an exact nonperturbative renormalization group equation. The location of the first order transition lines and the jump in the order parameter are computed quantitatively. At the triple point we find indications for partially universal behaviour. We suggest experiments that could help to determine the effective interactions between fermion pairs.Comment: 4 pages, 6 figures, LaTe

Electron transport and current fluctuations in short coherent conductors

Employing a real time effective action formalism we analyze electron transport and current fluctuations in comparatively short coherent conductors in the presence of electron-electron interactions. We demonstrate that, while Coulomb interaction tends to suppress electron transport, it may {\it strongly enhance} shot noise in scatterers with highly transparent conducting channels. This effect of excess noise is governed by the Coulomb gap observed in the current-voltage characteristics of such scatterers. We also analyze the frequency dispersion of higher current cumulants and emphasize a direct relation between electron-electron interaction effects and current fluctuations in disordered mesoscopic conductors.Comment: 16 pages, 4 figure

DC-transport in superconducting point contacts: a full counting statistics view

We present a comprehensive theoretical analysis of the dc transport properties of superconducting point contacts. We determine the full counting statistics for these junctions, which allows us to calculate not only the current or the noise, but all the cumulants of the current distribution. We show how the knowledge of the statistics of charge transfer provides an unprecedented level of understanding of the different transport properties for a great variety of situations. We illustrate our results with the analysis of junctions between BCS superconductors, contacts between superconductors with pair-breaking mechanisms and short diffusive bridges. We also discuss the temperature dependence of the different cumulants and show the differences with normal contacts.Comment: revtex4, 20 pages, 15 figure

Model Ensembles of Ecosystem Services Fill Global Certainty and Capacity Gaps

Sustaining ecosystem services (ES) critical to human wellbeing is hindered by many practitioners lacking access to ES models (‘the capacity gap’) or knowledge of the accuracy of available models (‘the certainty gap’), especially in the world’s poorer regions. We developed ensembles of multiple models at an unprecedented global scale for five ES of high policy relevance. Ensembles were 2-14% more accurate than individual models. Ensemble accuracy was not correlated with proxies for research capacity – indicating accuracy is distributed equitably across the globe and that countries less able to research ES suffer no accuracy penalty. By making these ES ensembles and associated accuracy estimates freely available, we provide globally consistent ES information that can support policy and decision making in regions with low data availability or low capacity for implementing complex ES models. Thus, we hope to reduce the capacity and certainty gaps impeding local to global-scale movement towards ES sustainability

Suunnitteluprosessiohje

Tämän opinnäytetyön aiheena oli suunnitteluprosessiohje. Opinnäytetyön tavoitteena oli tehdä Suomen Imurikeskus Oy:lle vakioidut toimintatavat laitteistojen suunnittelun kululle, ja selvittää mahdollinen kehitysvaihtoehto tiedonhallinnalle. Opinnäytetyössä käytiin lävitse Suomen Imurikeskus Oy:n laitteistojen valmistuksen eri vaiheita suunnittelijoiden osalta. Tämän perusteella kehitettiin vakioidut toimintatavat suunnitteluprosessiohjeeseen. Kehitysvaihtoehtona tiedonhallinnalle harkittiin Vertex Systems Oy:n Vertex Flow PDM/PLM -ohjelmistoa ja ohjelmistoon käytiin tutustumassa Vertex Systems Oy:n järjestämssä PLM-päivässä Tampereella. Lopputuloksena saatiin valmistettua Suomen Imurikeskus Oy:n käyttöön toimiva suunnitteluprosessiohje laitteistojen suunnitteluun. Suunnitteluprosessiohje sisältää ohjeistuksen laitteistojen suunnittelun eri vaiheille.The purpose of this thesis was to create engineering process manual for Suomen Imurikeskus Oy. The manual is meant to clarify the correct procedures for the process of appliance planning and alternative options for data management. In this thesis different phases of manufacturing were examined from Suomen Imurikeskus Oy’s designers point of view. Based on the thesis some standardized procedures were created for the engineering process manual. Vertex Systems' Vertex Flow PDM/PLM software was considered as an option for data management and the software was familiarized by visiting PLM-fair hosted by Vertex Systems Oy in Tampere. End result of the thesis was an engineering process manual for appliance planning to Suomen Imurikeskus Oy use. Engineering process manual includes instructions to different steps of appliance planning

Optimization of the derivative expansion in the nonperturbative renormalization group

We study the optimization of nonperturbative renormalization group equations truncated both in fields and derivatives. On the example of the Ising model in three dimensions, we show that the Principle of Minimal Sensitivity can be unambiguously implemented at order $\partial^2$ of the derivative expansion. This approach allows us to select optimized cut-off functions and to improve the accuracy of the critical exponents $\nu$ and $\eta$. The convergence of the field expansion is also analyzed. We show in particular that its optimization does not coincide with optimization of the accuracy of the critical exponents.Comment: 13 pages, 9 PS figures, published versio