1,739 research outputs found
The Ejecta Distributions of the Heavy Elements in the Cygnus Loop
We analyzed the metal distribution of the Cygnus Loop using 14 and 7
pointings observation data obtained by the \textit{Suzaku} and the
\textit{XMM-Newton} observatories. The spectral analysis shows that all the
spectra are well fitted by the two- non-equilibrium ionization plasma
model as shown by the earlier observations. From the best-fit parameters of the
high- component, we calculated the emission measures about various
elements and showed the metal distribution of the ejecta component. We found
that the distributions of Si and Fe are centered at the southwest of the
geometric center toward the blow-out region. From the best-fit parameters, we
also estimated the progenitor mass of the Cygnus Loop from our field of view
and the metal rich region with a radius of 25 arcmin from the metal center. The
result from the metal circle is similar to that from our entire FOV, which
suggests the mixing of the metal. From the results, we estimated the mass of
the progenitor star at 12-15\MO.Comment: 15 pages, 5 figures, PASJ, Vol.61, No.
Three Dimensional Nonlinear Joint Analysis for Assessment of Slope Stability
In this paper the behavior of an artificial slope, during a cyclic loading, is investigated by utilizing shaking table test and numerical simulation obtained from a finite element analysis. The effects of rock bolts and rope nets, used to stabilize the slope during earthquake, are investigated in several experimental and analytical cases. The slippage between rock bolt and soil is simulated by a nodal link element, placed at the contact area of rock bolt and soil. Using rock bolts and rope nets as reinforcement, affect the response of the model by reducing the maximum displacement of the slope along with a considerable decrease in maximum tensile stress. The developed cracks at the top of slope are also modeled with link element. When the cracks open, tensile stress can not develop across the opening and a tensile stress release may occur in that area which results in a redistribution of internal stresses in the slope
Superdeformed hypernuclei with antisymmetrized molecular dynamics
The response to the addition of a hyperon is investigated for the
deformed states such as superdeformation in Ca, Sc and Sc. In the present study, we use the antisymmetrized
molecular dynamics (AMD) model. It is pointed out that many kinds of deformed
bands appear in Sc and Sc. Especially, it is found that there
exists superdeformed states in Sc. By the addition of a
particle to Ca, Sc and Sc, it is predicted, for the first
time, that the superdeformed states exist in the hypernuclei Ca
and Sc. The manifestation of the dependence of the
-separation energy on nuclear deformation such as spherical, normal
deformation and superdeformation is shown in the energy spectra of
Ca, Sc and Sc hypernuclei.Comment: 24 pages, 8 figure
Advanced RO element obtained by new membrane and channel material
Introduction
Reverse osmosis (RO) membranes are regarded as the most powerful tools to solve global water problems, since they make it possible to supply high-grade water with low cost and low energy consumption. RO membrane technologies have made great progress in last 50 years. However, still more improvement of membrane performance is required to achieve lower energy consumption and higher water quality in seawater, brackish water, and tap water desalination field.
Toray has made efforts to elucidate dynamics of water molecules during water permeation process using neutron scattering and molecular dynamics simulation. Utilizing these results, new RO membranes with high water permeability was developed based on advanced molecular design of cross-linked polyamide pore structure. In addition, Toray created a new permeate channel material of element with low water flow resistance that enhanced water flux of the new RO membrane element.
Material and Method
Polyamide RO membranes were fabricated by interfacial polymerization of aromatic amines and carboxylic acid chlorides. Protuberance and pore structures of the polyamide RO membranes were analyzed by Transmission Electron Microscope (TEM) and molecular dynamics (MD) simulation. (Figure 1)
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The disintegrin echistatin in combination with doxorubicin targets high-metastatic human osteosarcoma overexpressing ανβ3 integrin in chick embryo and nude mouse models.
Echistatin, a cyclic RGD peptide, which is an antagonist of αvβ3 integrin (disintegrin), inhibited human osteosarcoma in the chick chorioallontoic membrane (CAM) model and tumor growth and pulmonary metastases in a nude mouse orthotopic model. A high-metastatic variant of human osteosarcoma, 143B-LM4, overexpressing αvβ3 integrin was used. Tumor angiogenesis by high-metastatic variant 143B-LM4 cells in the CAM was significantly inhibited by echistatin (P<0.05) as was overall growth. A doxorubicin (DOX)-echistatin combination inhibited orthotopic tumor growth compared to untreated control (P<0.01) or DOX alone (P<0.05) in nude mice. Tumor-bearing mice treated with the DOX-echistatin combination survived longer than those treated with DOX alone or control PBS (P<0.01 and P<0.01, respectively). Echistatin also inhibited experimental lung metastasis of 143B-LM4 cells in nude mice. These results suggest that DOX in combination with a disintegrin has potential to treat osteosarcoma and that αvβ3 integrin may be a target for osteosarcoma
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