Designing a cost-effective high-performance data acquisition system for measuring electronic systems

This paper discusses the design and layout of a low-cost high-performance data acquisition system PCB for taking voltage measurements in electronic systems. The system incorporates a high precision, external analog to digital converter (ADC) along with analog front-end circuitry to properly condition an applied input signal and achieve higher quality measurement capabilities than are possible with typical integrated (ADCs) found in microcontroller peripherals. The PCB is designed to easily interface with various microcontroller launchpads to provide a low-cost interface to a host PC for collecting and processing measured samples. The system is suitable for taking both DC and AC measurements with the potential for measuring more advanced AC characteristics such as signal to noise ratio and total harmonic distortion

Structural Design of Wing Twist for Pitch Control of Joined Wing Sensor Craft

This research investigated two aspects of the aft wing structure of a joined wing SensorCraft. First, the efficacy of a novel approach for incorporating wing twist for pitch control was analyzed. This design involved adding a spanwise sliding joint into the wing structure at the lower aft spar of the vehicle\u27s aft wing. Second, the joint section where the forward and aft wings connect and form the outboard wing was redesigned and analyzed to improve the load transmission between the wing spars. Using MSC.NASTRAN, linear and non-linear static analyses were performed to examine the efficiency of the wing twist sliding joint and the forces required to achieve sufficient angular deflections for control. MSC.Patran was then used to perform post-processing of the raw data. Several variations of sliding joint location and composite ply angles were conducted. The sliding joint produced marked improvement in angular deflection over the baseline configuration. Surprisingly, however, ply angle did not have a large effect on the resulting deflections. Additional sliding joints incorporated into the wing structure produced no notable improvements in the obtained deflections either. Although the strain induced into the structure by the aft wing twist was on the order of the aerodynamic forces alone, the force required to twist the wing was significantly reduced by adding the slit in all cases. Flutter speed did not differ notably by the addition of the slit into the aft wing, yet some reduction in buckling strength was noted. The redesigned joint planform does appear to recover some of the buckling resistance lost due to the slit

Quantum mechanics on non commutative spaces and squeezed states: a functional approach

We review here the quantum mechanics of some noncommutative theories in which no state saturates simultaneously all the non trivial Heisenberg uncertainty relations. We show how the difference of structure between the Poisson brackets and the commutators in these theories generically leads to a harmonic oscillator whose positions and momenta mean values are not strictly equal to the ones predicted by classical mechanics. This raises the question of the nature of quasi classical states in these models. We propose an extension based on a variational principle. The action considered is the sum of the absolute values of the expressions associated to the non trivial Heisenberg uncertainty relations. We first verify that our proposal works in the usual theory i.e we recover the known Gaussian functions. Besides them, we find other states which can be expressed as products of Gaussians with specific hyper geometrics. We illustrate our construction in two models defined on a four dimensional phase space: a model endowed with a minimal length uncertainty and the non commutative plane. Our proposal leads to second order partial differential equations. We find analytical solutions in specific cases. We briefly discuss how our proposal may be applied to the fuzzy sphere and analyze its shortcomings.Comment: 15 pages revtex. The title has been modified,the paper shortened and misprints have been corrected. Version to appear in JHE

Omega-3 fatty acids for breast cancer prevention and survivorship

Abstract Women with evidence of high intake ratios of the marine omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) relative to the omega-6 arachidonic acid have been found to have a reduced risk of breast cancer compared with those with low ratios in some but not all case–control and cohort studies. If increasing EPA and DHA relative to arachidonic acid is effective in reducing breast cancer risk, likely mechanisms include reduction in proinflammatory lipid derivatives, inhibition of nuclear factor-κB-induced cytokine production, and decreased growth factor receptor signaling as a result of alteration in membrane lipid rafts. Primary prevention trials with either risk biomarkers or cancer incidence as endpoints are underway but final results of these trials are currently unavailable. EPA and DHA supplementation is also being explored in an effort to help prevent or alleviate common problems after a breast cancer diagnosis, including cardiac and cognitive dysfunction and chemotherapy-induced peripheral neuropathy. The insulin-sensitizing and anabolic properties of EPA and DHA also suggest supplementation studies to determine whether these omega-3 fatty acids might reduce chemotherapy-associated loss of muscle mass and weight gain. We will briefly review relevant omega-3 fatty acid metabolism, and early investigations in breast cancer prevention and survivorship

On the Two q-Analogue Logarithmic Functions

There is a simple, multi-sheet Riemann surface associated with e_q(z)'s inverse function ln_q(w) for 0< q < 1. A principal sheet for ln_q(w) can be defined. However, the topology of the Riemann surface for ln_q(w) changes each time "q" increases above the collision point of a pair of the turning points of e_q(x). There is also a power series representation for ln_q(1+w). An infinite-product representation for e_q(z) is used to obtain the ordinary natural logarithm ln{e_q(z)} and the values of sum rules for the zeros "z_i" of e_q(z). For |z|<|z_1|, e_q(z)=exp{b(z)} where b(z) is a simple, explicit power series in terms of values of these sum rules. The values of the sum rules for the q-trigonometric functions, sin_q(z) and cos_q(z), are q-deformations of the usual Bernoulli numbers.Comment: This is the final version to appear in J.Phys.A: Math. & General. Some explict formulas added, and to update the reference

Regulation of hepatic autophagy by stress‐sensing transcription factor CREBH

Autophagy, a lysosomal degradative pathway in response to nutrient limitation, plays an important regulatory role in lipid homeostasis upon energy demands. Here, we demonstrated that the endoplasmic reticulum–tethered, stress‐sensing transcription factor cAMP‐responsive element‐binding protein, hepatic‐specific (CREBH) functions as a major transcriptional regulator of hepatic autophagy and lysosomal biogenesis in response to nutritional or circadian signals. CREBH deficiency led to decreased hepatic autophagic activities and increased hepatic lipid accumulation upon starvation. Under unfed or during energy‐demanding phases of the circadian cycle, CREBH is activated to drive expression of the genes encoding the key enzymes or regulators in autophagosome formation or autophagic process, including microtubule‐associated protein IB‐light chain 3, autophagy‐related protein (ATG)7, ATG2b, and autophagosome formation Unc‐51 like kinase 1, and the genes encoding functions in lysosomal biogenesis and homeostasis. Upon nutrient starvation, CREBH regulates and interacts with peroxisome proliferator–activated receptor α (PPARα) and PPARγ coactivator 1α to synergistically drive expression of the key autophagy genes and transcription factor EB, a master regulator of lysosomal biogenesis. Furthermore, CREBH regulates rhythmic expression of the key autophagy genes in the liver in a circadian‐dependent manner. In summary, we identified CREBH as a key transcriptional regulator of hepatic autophagy and lysosomal biogenesis for the purpose of maintaining hepatic lipid homeostasis under nutritional stress or circadian oscillation.—Kim, H., Williams, D., Qiu, Y., Song, Z., Yang, Z., Kimler, V., Goldberg, A., Zhang, R., Yang, Z., Chen, X., Wang, L., Fang, D., Lin, J. D., Zhang, K. Regulation of hepatic autophagy by stress‐sensing transcription factor CREBH. FASEB J. 33, 7896–7914 (2019). www.fasebj.orgPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154423/1/fsb2fj201802528r-sup-0001.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/154423/2/fsb2fj201802528r.pd