2d Seiberg-like dualities with an adjoint matter

We consider the analogue of Kutasov-Schwimmer-Seiberg duality for two-dimensional N = (2, 2) U(k) gauge theory with one adjoint X with the superpotential Tr Xl+1 and with fundamental and anti-fundamental chiral multiplets. We give the evidences for the proposed dualities by analytically proving that the elliptic genus of dual pair coincides with each other. For some of the dual pairs flowing to the superconformal field theory, we show the nonperturbative truncation of the chiral ring. For the theory with one adjoint and N-f > k fundamental fields, we argue the theory exhibits mass gap.111Ysciescopu

Binary Black Holes and Quantum Off-Shell Recursion

The quantum off-shell recursion provides an efficient and universal computational tool for loop-level scattering amplitudes. In this work, we present a new comprehensive computational framework based on the quantum off-shell recursion for binary black hole systems. Using the quantum perturbiner method, we derive the recursions and solve them explicitly up to two-loop order. We develop a power-counting prescription that enables the straightforward separation of classical diagrams. We also devise a classification scheme that optimizes the integration by parts (IBP) reduction process, which makes higher-loop calculations more tractable. By employing the soft expansion technique, we remove irrelevant terms from the loop integrands and express them in terms of master integrals. We classify the one-loop and the two-loop classical diagrams, and their loop integrands are represented by linear combinations of the master integrals. Finally, we explicitly calculate the classical scalar 2 to 2 amplitudes in the potential region up to the 3PM order and reproduce the known results.Comment: 86 pages, 8 figures and 1 tabl

Perturbations of General Relativity to All Orders and the General nthn^{\rm th} Order Terms

We derive all-order expressions for perturbations of the Einstein-Hilbert action and the Einstein equation with the general $n$-th order terms of the perturbative expansions. We investigate the perturbations in three different formulations of GR classified according to their fundamental fields. Remarkably, we find minimal building blocks that generate the entire perturbations in a convention of metric perturbations for each of our formulations. We show that the number of terms of perturbations grows linearly as the order of perturbations increases. We regard the convention as a reference and discuss how to generalise the results in the reference to other conventions of metric perturbations. As a consistency check, we compute graviton scattering amplitudes using the perturbiner method based on the perturbative Einstein equation. Finally we discuss how to generalise the results to curved backgrounds and incorporate additional matter.Comment: 35 page

Activation of CD147 with Cyclophilin A Induces the Expression of IFITM1 through ERK and PI3K in THP-1 Cells

CD147, as a receptor for Cyclophilins, is a multifunctional transmembrane glycoprotein. In order to identify genes that are induced by activation of CD147, THP-1 cells were stimulated with Cyclophilin A and differentially expressed genes were detected using PCR-based analysis. Interferon-induced transmembrane 1 (IFITM1) was detected to be induced and it was confirmed by RT-PCR and Western blot analysis. CD147-induced expression of IFITM1 was blocked by inhibitors of ERK, PI3K, or NF-κB, but not by inhibitors of p38, JNK, or PKC. IFITM1 appears to mediate inflammatory activation of THP-1 cells since cross-linking of IFITM1 with specific monoclonal antibody against it induced the expression of proinflammatory mediators such as IL-8 and MMP-9. These data indicate that IFITM1 is one of the pro-inflammatory mediators that are induced by signaling initiated by the activation of CD147 in macrophages and activation of ERK, PI3K, and NF-κB is required for the expression of IFITM1

Inhibitory Effects of Ambrosia trifida L. on the Development of Root Hairs and Protein Patterns of Radicles

Ambrosia trifida L. is designated as invasive alien species by the Act on the Conservation and Use of Biodiversity by the Ministry of Environment, Korea. The purpose of present paper was to investigate the inhibitory effects of aqueous extracts of A.trifida on the development of root hairs of Triticum aestivum L., and Allium tuberosum Rottler ex Spreng and the electrophoretic protein patterns of their radicles. The development of root hairs was inhibited by increasing of aqueous extract concentrations. Through SDS-PAGE, the electrophoretic protein bands of extracted proteins from their radicles were appeared in controls, but protein bands of specific molecular weight disappeared or weakened in treatments. In conclusion, inhibitory effects of A. trifida made two receptor species changed morphologically, and at the molecular level in early growth stage

Effects of a Four-Week Core Stability Exercise on Functional Movement and Balance in People with Mild Lower-limb Discomfort

This study aimed to investigate the effects of a short-term core stability exercise on functional movement and balance in people with mild lower-limb discomfort. Twenty people with mild lower-limb discomfort were randomly assigned to control (CG) and core stability exercise training groups (SG, n=10 each). The SG completed twenty 30-min training sessions consisting of Pilates exercises for four weeks. Functional movement, balance, and discomfort level were assessed before and after core stability exercise, using a functional movement test, balance test and visual analogue scale (VAS), respectively. A mixed ANOVA with repeated measures was performed to determine the differences. SG demonstrated a significant increase in hurdle step (p = 0.024, group × time effect) and shoulder mobility (p = 0.037, group × time effect). The dynamic balance scores were significantly increased from the baseline in both limbs (right, p = 0.007; left, p = 0.011, time effect). Post-hoc pairwise comparisons indicated these increases were significant only in SG. Additionally, ankle pain was significantly reduced in SG (p = 0.023, group × time effect). This study highlights that four weeks of core stability exercise can positively affect the lower limbs’ functional movement and balance in people with mild lower-limb discomfort

Inhibitory Effects of Ambrosia trifida L. on the Development of Root Hairs and Protein Patterns of Radicles

Ambrosia trifida L. is designated as invasive alien species by the Act on the Conservation and Use of Biodiversity by the Ministry of Environment, Korea. The purpose of present paper was to investigate the inhibitory effects of aqueous extracts of A.trifida on the development of root hairs of Triticum aestivum L., and Allium tuberosum Rottler ex Spreng and the electrophoretic protein patterns of their radicles. The development of root hairs was inhibited by increasing of aqueous extract concentrations. Through SDS-PAGE, the electrophoretic protein bands of extracted proteins from their radicles were appeared in controls, but protein bands of specific molecular weight disappeared or weakened in treatments. In conclusion, inhibitory effects of A. trifida made two receptor species changed morphologically, and at the molecular level in early growth stage

Inhibitory Effects of Ambrosia trifida L. on the Development of Root Hairs and Protein Patterns of Radicles

Ambrosia trifida L. is designated as invasive alien species by the Act on the Conservation and Use of Biodiversity by the Ministry of Environment, Korea. The purpose of present paper was to investigate the inhibitory effects of aqueous extracts of A.trifida on the development of root hairs of Triticum aestivum L., and Allium tuberosum Rottler ex Spreng and the electrophoretic protein patterns of their radicles. The development of root hairs was inhibited by increasing of aqueous extract concentrations. Through SDS-PAGE, the electrophoretic protein bands of extracted proteins from their radicles were appeared in controls, but protein bands of specific molecular weight disappeared or weakened in treatments. In conclusion, inhibitory effects of A. trifida made two receptor species changed morphologically, and at the molecular level in early growth stage

BH3-only Protein Noxa Is a Mediator of Hypoxic Cell Death Induced by Hypoxia-inducible Factor 1α

Hypoxia is a common cause of cell death and is implicated in many disease processes including stroke and chronic degenerative disorders. In response to hypoxia, cells express a variety of genes, which allow adaptation to altered metabolic demands, decreased oxygen demands, and the removal of irreversibly damaged cells. Using polymerase chain reaction–based suppression subtractive hybridization to find genes that are differentially expressed in hypoxia, we identified the BH3-only Bcl-2 family protein Noxa. Noxa is a candidate molecule mediating p53-induced apoptosis. We show that Noxa promoter responds directly to hypoxia via hypoxia-inducible factor (HIF)-1α. Suppression of Noxa expression by antisense oligonucleotides rescued cells from hypoxia-induced cell death and decreased infarction volumes in an animal model of ischemia. Further, we show that reactive oxygen species and resultant cytochrome c release participate in Noxa-mediated hypoxic cell death. Altogether, our results show that Noxa is induced by HIF-1α and mediates hypoxic cell death