Understanding Oriental Medicine Using a Systems Approach

Two international meetings, the International Physiome Symposium 2008 and the Workshop on Systems Biology (SB) and Oriental Medicine (OM), were held to discuss the most appropriate scientific tools to research OM. Participants agreed that since OM is holistic medicine it needs a systems approach such as SB. However, SB itself is still a long way from identifying the high-level organization processes in the biological system that might correlate with concepts in OM. As such, a modest goal of launching a project to examine the problems of translation and interpretation of OM concepts would be the first step

Differences in the Tongue Features of Primary Dysmenorrhea Patients and Controls over a Normal Menstrual Cycle

Background. The aims of this study were to investigate the relationships between tongue features and the existence of menstrual pain and to provide basic information regarding the changes in tongue features during a menstrual cycle. Methods. This study was conducted at the Kyung Hee University Medical Center. Forty-eight eligible participants aged 20 to 29 years were enrolled and assigned to two groups according to their visual analogue scale (VAS) scores. Group A included 24 females suffering from primary dysmenorrhea (PD) caused by qi stagnation and blood stasis syndrome with VAS ≥ 4. In contrast, Group B included 24 females with few premenstrual symptoms and VAS < 4. All participants completed four visits (menses-follicular-luteal-menses phases), and the tongue images were taken by using a computerized tongue image analysis system (CTIS). Results. The results revealed that the tongue coating color value and the tongue coating thickness in the PD group during the menstrual phase were significantly lower than those of the control group (P=0.031 and P=0.029, resp.). Conclusions. These results suggest that the tongue features obtained from the CTIS may serve as a supplementary means for the differentiation of syndromes and the evaluation of therapeutic effect and prognosis in PD. Trial Registration. This trial was registered with Clinical Research Information Service, registration number KCT0001604, registered on 27 August 2015

Some results for uniformly L -Lipschitzian mappings in Banach spaces

AbstractThe purpose of this work is to prove a strong convergence theorem for a pair of uniformly L-Lipschitzian mappings in Banach spaces. The results presented in the work improve and extend some recent results of Chang [S.S. Chang, Some results for asymptotically pseudo-contractive mappings and asymptotically nonexpansive mappings, Proc. Amer. Math. Soc. 129 (2001) 845–853], Cho et al [Y.J. Cho, J.I. Kang, H.Y. Zhou, Approximating common fixed points of asymptotically nonexpansive mappings, Bull. Korean Math. Soc. 42 (2005) 661–670], Ofoedu [E.U. Ofoedu, Strong convergence theorem for uniformly L-Lipschitzian asymptotically pseudocontractive mapping in a real Banach space, J. Math. Anal. Appl. 321 (2006) 722–728], Schu [J. Schu, Iterative construction of fixed point of asymptotically nonexpansive mappings, J. Math. Anal. Appl. 158 (1991) 407–413] and Zeng [L.C. Zeng, On the iterative approximation for asymptotically pseudo-contractive mappings in uniformly smooth Banach spaces, Chinese Math. Ann. 26 (2005) 283–290 (in Chinese); L.C. Zeng, On the approximation of fixed points for asymptotically nonexpansive mappings in Banach spaces, Acta Math. Sci. 23 (2003) 31–37 (in Chinese)]

Clinical disease characteristics according to karyotype in Turner syndrome

Purpose : Turner syndrome (TS) is a disorder in which various anomalies can be accompanied, especially cardiovascular, renal, thyroid and auditory problems. The aim of this study is to identify the incidence of these disorders in patients with TS according to karyotype. Methods : We reviewed medical records of 90 patients with TS diagnosed by chromosomal analysis in 4 hospitals from Jan 1998 to Dec 2007. We evaluated these cases by prepared protocol of 4 medical problems. Results : The distribution of karyotype was 45,X (47.8&#37;), mosaic pattern (34.4&#37;) and structural aberration group (17.8 &#37;). Renal anomalies, cardiovascular anomalies, thyroid disorders and auditory problems are accompanied in 4.4&#37;, 10.0 &#37;, 11.1&#37; and 5.6&#37;, respectively. 45,X group had renal anomalies (7.0&#37;), cardiovascular anomalies (18.6&#37;), thyroid disorders (9.3&#37;) and auditory problems (11.6&#37;). Mosaic group had renal anomalies (3.2&#37;), thyroid disorders (12.9&#37;), no cardiovascular anomalies and auditory problems. Structural aberration group had cardiovascular anomalies (6.3&#37;), thyroid disorders (12.5&#37;) and no other 2 problems. Patients with 45,X group had a significant higher incidence of cardiovascular anomalies (P&#61;0.025). Conclusion : Our results indicate that there are differences clinically according to karyotype of TS, especially in incidence of cardiovascular anomalies

A Fuzzy-Based Multimedia Content Retrieval Method Using Mood Tags and Their Synonyms in Social Networks

The preferences of Web information purchasers are rapidly evolving. Cost-effectiveness is now becoming less regarded than cost-satisfaction, which emphasizes the purchaser’s psychological satisfaction. One method to improve a user’s cost-satisfaction in multimedia content retrieval is to utilize the mood inherent in multimedia items. An example of applications using this method is SNS (Social Network Services), which is based on folksonomy, but its applications encounter problems due to synonyms. In order to solve the problem of synonyms in our previous study, the mood of multimedia content is represented with arousal and valence (AV) in Thayer’s two-dimensional model as its internal tag. Although some problems of synonyms could now be solved, the retrieval performance of the previous study was less than that of a keyword-based method. In this paper, a new method that can solve the synonym problem is proposed, while simultaneously maintaining the same performance as the keyword-based approach. In the proposed method, a mood of multimedia content is represented with a fuzzy set of 12 moods of the Thayer model. For the analysis, the proposed method is compared with two methods, one based on AV value and the other based on keyword. The analysis results demonstrate that the proposed method is superior to the two methods

Feature Selection from a Facial Image for Distinction of Sasang Constitution

Recently, oriental medicine has received attention for providing personalized medicine through consideration of the unique nature and constitution of individual patients. With the eventual goal of globalization, the current trend in oriental medicine research is the standardization by adopting western scientific methods, which could represent a scientific revolution. The purpose of this study is to establish methods for finding statistically significant features in a facial image with respect to distinguishing constitution and to show the meaning of those features. From facial photo images, facial elements are analyzed in terms of the distance, angle and the distance ratios, for which there are 1225, 61 250 and 749 700 features, respectively. Due to the very large number of facial features, it is quite difficult to determine truly meaningful features. We suggest a process for the efficient analysis of facial features including the removal of outliers, control for missing data to guarantee data confidence and calculation of statistical significance by applying ANOVA. We show the statistical properties of selected features according to different constitutions using the nine distances, 10 angles and 10 rates of distance features that are finally established. Additionally, the Sasang constitutional meaning of the selected features is shown here

Development of pulse diagnostic devices in Korea

AbstractIn Korean medicine, pulse diagnosis is one of the important methods for determining the health status of a patient. For over 40 years, electromechanical pulse diagnostic devices have been developed to objectify and quantify pulse diagnoses. In this paper, we review previous research and development for pulse diagnostic devices according to various fields of study: demand analysis and current phase, literature studies, sensors, actuators, systems, physical quantity studies, clinical studies, and the U-health system. We point out some confusing issues that have been naively accepted without strict verification: original pressure pulse waveform and derivative pressure pulse waveform, pressure signals and other signal types, and minutely controlled pressure exertion issues. We then consider some technical and clinical issues to achieve the development of a pulse diagnostic device that is appropriate both technically and in terms of Korean medicine. We hope to show the history of pulse diagnostic device research in Korea and propose a proper method to research and develop these devices

Comparison of Sasang Constitutional Medicine, Traditional Chinese Medicine and Ayurveda

Sasang constitutional medicine (SCM), traditional Chinese medicine (TCM) and Ayurveda are three different forms of Asian traditional medicine. Although these traditions share a lot in common as holistic medicines, the different philosophical foundations found in each confer distinguishing attributes and unique qualities. SCM is based on a constitution-based approach, and is in this way relatively more similar to the Ayurvedic tradition than to the TCM, although many of the basic SCM theories were originally derived from TCM, a syndrome-based medicine. SCM and TCM use the same botanical materials that are distributed mainly in the East Asian region, but the basic principles of usage and the underlying rationale are completely different from each other. Meanwhile, the principles of the Ayurvedic use of botanical resources are very similar to those seen in SCM, but the medicinal herbs used in Ayurveda generally originate from the West Asian region which displays a different spectrum of flora

Prevalence of Metabolic Syndrome according to Sasang Constitutional Medicine in Korean Subjects

Metabolic syndrome (MS) is a complex disorder defined by a cluster of abdominal obesity, atherogenic dyslipidemia, hyperglycemia, and hypertension; the condition is recognized as a risk factor for diabetes and cardiovascular disease. This study assessed the effects of the Sasang constitution group (SCG) on the risk of MS in Korean subjects. We have analyzed 1,617 outpatients of Korean oriental medicine hospitals who were classified into three SCGs, So-Yang, So-Eum, and Tae-Eum. Significant differences were noted in the prevalence of MS and the frequencies of all MS risk factors among the three SCGs. The odds ratios for MS as determined via multiple logistic regression analysis were 2.004 for So-Yang and 4.521 for Tae-Eum compared with So-Eum. These results indicate that SCG may function as a significant risk factor of MS; comprehensive knowledge of Sasang constitutional medicine may prove helpful in predicting susceptibility and developing preventive care techniques for MS

Review on the current trends in tongue diagnosis systems

AbstractTongue diagnosis is an essential process to noninvasively assess the condition of a patient's internal organs in traditional medicine. To obtain quantitative and objective diagnostic results, image acquisition and analysis devices called tongue diagnosis systems (TDSs) are required. These systems consist of hardware including cameras, light sources, and a ColorChecker, and software for color correction, segmentation of tongue region, and tongue classification. To improve the performance of TDSs, various types TDSs have been developed. Hyperspectral imaging TDSs have been suggested to acquire more information than a two-dimensional (2D) image with visible light waves, as it allows collection of data from multiple bands. Three-dimensional (3D) imaging TDSs have been suggested to provide 3D geometry. In the near future, mobile devices like the smart phone will offer applications for assessment of health condition using tongue images. Various technologies for the TDS have respective unique advantages and specificities according to the application and diagnostic environment, but this variation may cause inconsistent diagnoses in practical clinical applications. In this manuscript, we reviewed the current trends in TDSs for the standardization of systems. In conclusion, the standardization of TDSs can supply the general public and oriental medical doctors with convenient, prompt, and accurate information with diagnostic results for assessing the health condition