Technology Development Plan for the Baseline Detector System of the X-Ray Microcalorimeter Spectrometer (XMS) of the International X-Ray Observatory (IXO)

The primary purpose of this document is to present the technology development plan for the XMS detector system. It covers the current status (including assessment of the Technology Readiness Level, TRL, and a justification of the level assigned), the roadmap to progress to a level between TRL 5 and TRL 6 by the middle of 2012, and an assessment of the associated cost. A secondary purpose of this document is to address the Action Items raised at the XMS Phase-A Study Mid-Term Review that pertain to the detector system (AI #4, #8, and #9)

Physics of the Cosmos (PCOS) Program Technology Development 2018

We present a final report on our program to raise the Technology Readiness Level (TRL) of enhanced chargecoupleddevice (CCD) detectors capable of meeting the requirements of Xray grating spectrometers (XGS) and widefield Xray imaging instruments for small, medium, and large missions. Because they are made of silicon, all Xray CCDs require blocking filters to prevent corruption of the Xray signal by outofband, mainly optical and nearinfrared (nearIR) radiation. Our primary objective is to demonstrate technology that can replace the fragile, extremely thin, freestanding blocking filter that has been standard practice with a much more robust filter deposited directly on the detector surface. Highperformance, backilluminated CCDs have flown with freestanding filters (e.g., one of our detectors on Suzaku), and other relatively lowperformance CCDs with directly deposited filters have flown (e.g., on the Xray Multimirror MissionNewton, XMMNewton Reflection Grating Spectrometer, RGS). At the inception of our program, a highperformance, backilluminated CCD with a directly deposited filter has not been demonstrated. Our effort will be the first to show such a filter can be deposited on an Xray CCD that meets the requirements of a variety of contemplated future instruments. Our principal results are as follows: i) we have demonstrated a process for direct deposition of aluminum optical blocking filters on backilluminated MIT Lincoln Laboratory CCDs. Filters ranging in thickness from 70 nm to 220 nm exhibit expected bulk visibleband and Xray transmission properties except in a small number (affecting 1% of detector area) of isolated detector pixels ("pinholes"), which show higherthanexpected visibleband transmission; ii) these filters produce no measurable degradation in softXray spectral resolution, demonstrating that direct filter deposition is compatible with the MIT Lincoln Laboratory backillumination process; iii) we have shown that under sufficiently intense visible and nearIR illumination, outofband light can enter the detector through its sidewalls and mounting surfaces, compromising detector performance. This 'sidewall leakage' has been observed, for example, by a previous experiment on the International Space Station during its orbitday operations. We have developed effective countermeasures for this sidewall leakage; iv) we developed an exceptionally productive collaboration with the Regolith Xray Imaging Spectrometer (REXIS) team. REXIS is a student instrument now flying on the Origins Spectral Interpretation Resource Identification Security - Regolith Explorer (OSIRISREx) mission. REXIS students participated in our filter development program, adopted our technology for their flight instrument, and raised the TRL of this technology beyond our initial goals. This Strategic Astrophysics Technology (SAT) project, a collaboration between the MKI and MIT Lincoln Laboratory, began July 1, 2012, and ended on June 30, 2018

Cluster randomized trial comparing standard versus enhanced implementation strategies for improving outreach to persons with SMI: 12-month results

http://deepblue.lib.umich.edu/bitstream/2027.42/134545/1/13012_2015_Article_940.pd

Cluster randomized adaptive implementation trial comparing a standard versus enhanced implementation intervention to improve uptake of an effective re-engagement program for patients with serious mental illness

Abstract Background Persons with serious mental illness (SMI) are disproportionately burdened by premature mortality. This disparity is exacerbated by poor continuity of care with the health system. The Veterans Health Administration (VA) developed Re-Engage, an effective population-based outreach program to identify veterans with SMI lost to care and to reconnect them with VA services. However, such programs often encounter barriers getting implemented into routine care. Adaptive designs are needed when the implementation intervention requires augmentation within sites that do not initially respond to an initial implementation intervention. This protocol describes the methods used in an adaptive implementation design study that aims to compare the effectiveness of a standard implementation strategy (Replicating Effective Programs, or REP) with REP enhanced with External Facilitation (enhanced REP) to promote the uptake of Re-Engage. Methods/Design This study employs a four-phase, two-arm, longitudinal, clustered randomized trial design. VA sites (n = 158) across the United States with a designated Re-Engage provider, at least one Veteran with SMI lost to care, and who received standard REP during a six-month run-in phase. Subsequently, 88 sites with inadequate uptake were stratified at the cluster level by geographic region (n = 4) and VA regional service network (n = 20) and randomized to REP (n = 49) vs. enhanced REP (n = 39) in phase two. The primary outcome was the percentage of veterans on each facility outreach list documented on an electronic web registry. The intervention was at the site and network level and consisted of standard REP versus REP enhanced by external phone facilitation consults. At 12 months, enhanced REP sites returned to standard REP and 36 sites with inadequate participation received enhanced REP for six months in phase three. Secondary implementation outcomes included the percentage of veterans contacted directly by site providers and the percentage re-engaged in VA health services. Discussion Adaptive implementation designs consisting of a sequence of decision rules that are tailored based on a site’s uptake of an effective program may produce more relevant, rapid, and generalizable results by more quickly validating or rejecting new implementation strategies, thus enhancing the efficiency and sustainability of implementation research and potentially leading to the rollout of more cost-efficient implementation strategies. Trial registration Current Controlled Trials ISRCTN21059161 .http://deepblue.lib.umich.edu/bitstream/2027.42/112609/1/13012_2013_Article_711.pd

Organizational factors and depression management in community-based primary care settings

Abstract Background Evidence-based quality improvement models for depression have not been fully implemented in routine primary care settings. To date, few studies have examined the organizational factors associated with depression management in real-world primary care practice. To successfully implement quality improvement models for depression, there must be a better understanding of the relevant organizational structure and processes of the primary care setting. The objective of this study is to describe these organizational features of routine primary care practice, and the organization of depression care, using survey questions derived from an evidence-based framework. Methods We used this framework to implement a survey of 27 practices comprised of 49 unique offices within a large primary care practice network in western Pennsylvania. Survey questions addressed practice structure (e.g., human resources, leadership, information technology (IT) infrastructure, and external incentives) and process features (e.g., staff performance, degree of integrated depression care, and IT performance). Results The results of our survey demonstrated substantial variation across the practice network of organizational factors pertinent to implementation of evidence-based depression management. Notably, quality improvement capability and IT infrastructure were widespread, but specific application to depression care differed between practices, as did coordination and communication tasks surrounding depression treatment. Conclusions The primary care practices in the network that we surveyed are at differing stages in their organization and implementation of evidence-based depression management. Practical surveys such as this may serve to better direct implementation of these quality improvement strategies for depression by improving understanding of the organizational barriers and facilitators that exist within both practices and practice networks. In addition, survey information can inform efforts of individual primary care practices in customizing intervention strategies to improve depression management.http://deepblue.lib.umich.edu/bitstream/2027.42/78269/1/1748-5908-4-84.xmlhttp://deepblue.lib.umich.edu/bitstream/2027.42/78269/2/1748-5908-4-84-S1.PDFhttp://deepblue.lib.umich.edu/bitstream/2027.42/78269/3/1748-5908-4-84.pdfPeer Reviewe

A review of the role of the Atlantic meridional overturning circulation in Atlantic multidecadal variability and associated climate impacts

By synthesizing recent studies employing a wide range of approaches (modern observations, paleo reconstructions, and climate model simulations), this paper provides a comprehensive review of the linkage between multidecadal Atlantic Meridional Overturning Circulation (AMOC) variability and Atlantic Multidecadal Variability (AMV) and associated climate impacts. There is strong observational and modeling evidence that multidecadal AMOC variability is a crucial driver of the observed AMV and associated climate impacts and an important source of enhanced decadal predictability and prediction skill. The AMOC‐AMV linkage is consistent with observed key elements of AMV. Furthermore, this synthesis also points to a leading role of the AMOC in a range of AMV‐related climate phenomena having enormous societal and economic implications, for example, Intertropical Convergence Zone shifts; Sahel and Indian monsoons; Atlantic hurricanes; El Niño–Southern Oscillation; Pacific Decadal Variability; North Atlantic Oscillation; climate over Europe, North America, and Asia; Arctic sea ice and surface air temperature; and hemispheric‐scale surface temperature. Paleoclimate evidence indicates that a similar linkage between multidecadal AMOC variability and AMV and many associated climate impacts may also have existed in the preindustrial era, that AMV has enhanced multidecadal power significantly above a red noise background, and that AMV is not primarily driven by external forcing. The role of the AMOC in AMV and associated climate impacts has been underestimated in most state‐of‐the‐art climate models, posing significant challenges but also great opportunities for substantial future improvements in understanding and predicting AMV and associated climate impacts

Accelerator experiments with soft protons and hyper-velocity dust particles: application to ongoing projects of future X-ray missions

We report on our activities, currently in progress, aimed at performing accelerator experiments with soft protons and hyper-velocity dust particles. They include tests of different types of X-ray detectors and related components (such as filters) and measurements of scattering of soft protons and hyper-velocity dust particles off X-ray mirror shells. These activities have been identified as a goal in the context of a number of ongoing space projects in order to assess the risk posed by environmental radiation and dust and qualify the adopted instrumentation with respect to possible damage or performance degradation. In this paper we focus on tests for the Silicon Drift Detectors (SDDs) used aboard the LOFT space mission. We use the Van de Graaff accelerators at the University of T\"ubingen and at the Max Planck Institute for Nuclear Physics (MPIK) in Heidelberg, for soft proton and hyper-velocity dust tests respectively. We present the experimental set-up adopted to perform the tests, status of the activities and some very preliminary results achieved at present time.Comment: Proceedings of SPIE, Vol. 8443, Paper No. 8443-24, 201