Quasi-3 DOF Rehabilitation System for Upper Limbs, “PLEMO”

Non

"Hybrid-PLEMO", Rehabilitation System for Upper Limbs with Active / Passive Force Feedback Mode

Non

Transfer Routing of Ore Yard by Decentralized Agent Method

In steel works, iron ores are stored in ore yard and sent to various plants of down stream accoding to transfer requests. To attain stable operation, it is neccesary to keep a certain allowable stock level in ore tanks of all plants. To this purpose, ore transfer routing method has been developed based on decentralized agent method. In case of disaster such as a big earthquake or a big fire, damages in the facilities of industrial complex may be unavoidable. In this paper, decentralized optimization method is tested to cope with such emergencies. Decentralized agents corresponding to kind of ore make their own transfer route plan exchanging information with others. As the application of the proposed method, transfer scheduling in ore yard in steel works are made in case of destruction of transfer facilities

Are Dysregulated Inflammatory Responses to Commensal Bacteria Involved in the Pathogenesis of Hepatobiliary-Pancreatic Autoimmune Disease? An Analysis Using Mice Models of Primary Biliary Cirrhosis and Autoimmune Pancreatitis

The etiopathogenesis of many autoimmune disorders has not been identified. The aim of this paper is to focus on the involvement of bacterial exposure in the pathogenesis of primary biliary cirrhosis (PBC) and autoimmune pancreatitis (AIP), both of which are broadly categorized as autoimmune disorders involving hepatobiliary-pancreatic lesions. Avirulent and/or commensal bacteria, which may have important role(s) as initiating factors in the pathogenesis of autoimmune disorders such as PBC and AIP, will be emphasized

Transfer Planning of Molten Metals in Steel Worksby Decentralized Agent

In steel works, molten metals discharged from blast furnace are put into a pan for transportation called torpedo and transported to steel making factory by a locomotive. In molten metals transportation, it becomes issues to prevent temperature drop of molten metals for stable production of down stream plants to shorten transportation time. Therefore it is necessary to make an appropriate plan for molten metals transfer considering the production and the transportation simultaneously. In this paper, molten metals transfer planning method is proposed including production scheduling. That is, torpedo schedule, transfer request assignment and route plan of locomotives are optimized according to each objective

Vaporized Hydrogen Peroxide and Ozone Gas Synergistically Reduce Prion Infectivity on Stainless Steel Wire

Prions are infectious agents causing prion diseases, which include Creutzfeldt–Jakob disease (CJD) in humans. Several cases have been reported to be transmitted through medical instruments that were used for preclinical CJD patients, raising public health concerns on iatrogenic transmissions of the disease. Since preclinical CJD patients are currently difficult to identify, medical instruments need to be adequately sterilized so as not to transmit the disease. In this study, we investigated the sterilizing activity of two oxidizing agents, ozone gas and vaporized hydrogen peroxide, against prions fixed on stainless steel wires using a mouse bioassay. Mice intracerebrally implanted with prion-contaminated stainless steel wires treated with ozone gas or vaporized hydrogen peroxide developed prion disease later than those implanted with control prion-contaminated stainless steel wires, indicating that ozone gas and vaporized hydrogen peroxide could reduce prion infectivity on wires. Incubation times were further elongated in mice implanted with prion-contaminated stainless steel wires treated with ozone gas-mixed vaporized hydrogen peroxide, indicating that ozone gas mixed with vaporized hydrogen peroxide reduces prions on these wires more potently than ozone gas or vaporized hydrogen peroxide. These results suggest that ozone gas mixed with vaporized hydrogen peroxide might be more useful for prion sterilization than ozone gas or vaporized hydrogen peroxide alone

Cases of primary malignant melanoma and melanocytosis of the esophagus observed by magnifying endoscopy : Application to differential diagnosis : case series

Rationale: Primary malignant melanoma of the esophagus (PMME) is a rare disease with an extremely poor prognosis. In contrast, melanocytosis is a benign condition defined as melanocytic proliferation with melanin deposition. PMME is often accompanied by melanocytosis, but differentiating between them is difficult because of their similar appearance. Patient concerns: Here, we reported 3 PMME cases, 2 with melanocytosis. Diagnoses: Magnifying endoscopy revealed characteristic non-uniform pigmented spots along deformed intrapapillary capillary loops (IPCLs) in PMME, while melanocytosis showed fine granule-like or linearly arranged spots and intact IPCLs. Interventions: The patients underwent endoscopic or surgical resection of each lesion. Outcomes: Histologically, magnified images reflected melanocyte growth. For cases 1 and 2, the patients remained disease-free for 61 and 15 months after endoscopic resection, respectively. In case 3, liver metastases developed two months after surgery, and the patient died from liver failure after six months. Lessons: This is the first report describing differences in magnified views of the 2 diseases, which aids a differential diagnosis

Development of a Super-Small Solid Rocket Motor for OMOTENASHI

Background of the OMOTENASHI Mission. To be launched by NASA’s SLS Artemis 1 in the early 2020s, OMOTENASHI will be one of the 13 CubeSats launched as secondary payloads. With a size of 6U (113×239×366 mm) and a mass of CubeSat, it is the world’s smallest moon lander. Aims to land on the moon