159 research outputs found
The Journal of Gynecologic Oncology and the Asian Society of Gynecologic Oncology: the history, the present and the future
Surface mass balance contributions to acceleration of Antarctic ice mass loss during 2003-2013
Recent observations from satellite gravimetry (the Gravity Recovery and Climate Experiment (GRACE) mission) suggest an acceleration of ice mass loss from the Antarctic Ice Sheet (AIS). The contribution of surface mass balance changes (due to variable precipitation) is compared with GRACE-derived mass loss acceleration by assessing the estimated contribution of snow mass from meteorological reanalysis data. We find that over much of the continent, the acceleration can be explained by precipitation anomalies. However, on the Antarctic Peninsula and other parts of West Antarctica, mass changes are not explained by precipitation and are likely associated with ice discharge rate increases. The total apparent GRACE acceleration over all of the AIS between 2003 and 2013 is −13.6 ± 7.2 Gt/yr^2. Of this total, we find that the surface mass balance component is −8.2 ± 2.0 Gt/yr^2. However, the GRACE estimate appears to contain errors arising from the atmospheric pressure fields used to remove air mass effects. The estimated acceleration error from this effect is about 9.8 ± 5.8 Gt/yr^2. Correcting for this yields an ice discharge acceleration of −15.1 ± 6.5 Gt/yr^2
Active subglacial lakes and channelized water flow beneath the Kamb Ice Stream
We identify two previously unknown subglacial lakes beneath the stagnated trunk of the Kamb Ice Stream (KIS). Rapid fill-drain hydrologic events over several months are inferred from surface height changes measured by CryoSat-2 altimetry and indicate that the lakes are probably connected by a subglacial drainage network, whose structure is inferred from the regional hydraulic potential and probably links the lakes. The sequential fill-drain behavior of the subglacial lakes and concurrent rapid thinning in a channel-like topographic feature near the grounding line implies that the subglacial water repeatedly flows from the region above the trunk to the KIS grounding line and out beneath the Ross Ice Shelf. Ice shelf elevation near the hypothesized outlet is observed to decrease slowly during the study period. Our finding supports a previously published conceptual model of the KIS shutdown stemming from a transition from distributed flow to well-drained channelized flow of subglacial water. However, a water-piracy hypothesis in which the KIS subglacial water system is being starved by drainage in adjacent ice streams is also supported by the fact that the degree of KIS trunk subglacial lake activity is relatively weaker than those of the upstream lakes.OAIID:RECH_ACHV_DSTSH_NO:T201501631RECH_ACHV_FG:RR00200001ADJUST_YN:EMP_ID:A079127CITE_RATE:4.906FILENAME:2016_Kim_TC.pdfDEPT_NM:지구과학교육과EMAIL:[email protected]_YN:YFILEURL:https://srnd.snu.ac.kr/eXrepEIR/fws/file/0f782ccb-87d7-4af5-89fc-9ed5599fd0f7/linkCONFIRM:
Encoder-decoder multimodal speaker change detection
The task of speaker change detection (SCD), which detects points where
speakers change in an input, is essential for several applications. Several
studies solved the SCD task using audio inputs only and have shown limited
performance. Recently, multimodal SCD (MMSCD) models, which utilise text
modality in addition to audio, have shown improved performance. In this study,
the proposed model are built upon two main proposals, a novel mechanism for
modality fusion and the adoption of a encoder-decoder architecture. Different
to previous MMSCD works that extract speaker embeddings from extremely short
audio segments, aligned to a single word, we use a speaker embedding extracted
from 1.5s. A transformer decoder layer further improves the performance of an
encoder-only MMSCD model. The proposed model achieves state-of-the-art results
among studies that report SCD performance and is also on par with recent work
that combines SCD with automatic speech recognition via human transcription.Comment: 5 pages, accepted for presentation at INTERSPEECH 202
Интернационализация подготовки научных кадров в развитых европейских странах:проблемы и уроки
Показаны формы международного сотрудничества в рамках интернационализации докторского образования, стратегии интернационализации высшего образования в целом и докторского в частности. Описан накопленный опыт, сформулированы основные уроки и полезные идеи, вытекающие из него.Показано форми міжнародного співробітництва у рамках інтернаціоналізації докторської освіти, стратегії інтернаціоналізації вищої освіти загалом та докторської зокрема. Описано накопичений досвід, сформульовано основні уроки та корисні ідеї, що випливають з нього.Forms of international cooperation in internationalization of doctoral education, strategies of internationalization in higher education in general and doctoral education in particular are shown. Experiences accumulated in this field are described; main lessons and useful ideas born from the experiences are outlined
Specific Radius Change of Quantum Dot inside the Lipid Bilayer by Charge Effect of Lipid Head-Group
We studied the quantum dot-liposome complex (QLC), which is the giant unilamellar vesicle with quantum dots (QDs) incorporated in its lipid bilayer. A spin coating method in conjunction with the electroformation technique yielded vesicles with highly homogeneous unilamellar structure. We observed QD size dependence of the QLC formation: QLCs form with blue, green and yellow-emission QD (core radius ~1.05 nm, 1.25 nm and 1.65 nm) but not with red-emission QD (core radius ~2.5 nm). In order to explain this size dependence, we made a simple model explaining the QD size effect on QLC formation in terms of the molecular packing parameter and the lipid conformational change. This model predicts that QDs below a certain critical size (radius ≈ 1.8 nm) can stably reside in a lipid bilayer of 4 - 5 nm in thickness for Egg-PC lipids. This is consistent with our previous experimental results. In the case of red-emission QD, QD-aggregations are only observed on the fluorescent microscopy instead of QLC. We expected that the reduction of packing parameter (P) would lead to the change of specific QD radius. This prediction could be verified by our experimental observation of the shift of the specific QD size by mixing DOPG
Acute Spontaneous Subdural Hematoma of Arterial Origin
Acute spontaneous subdural hematoma (SDH) of arterial origin is very rare. We report a case of acute spontaneous SDH that showed contrast media extravasation from cortical artery on angiograms. A 58-year-old male patient developed sudden onset headache and right hemiparesis. Brain CT scan demonstrated acute SDH at left convexity. The patient was drowsy mentality on admission. He had no history of head trauma. Cerebral angiography was performed and revealed a localized extravasation of the contrast media from distal cortical MCA branch. After angiography, the patient deteriorated to comatose mentality. Decompressive craniectomy for removal of SDH was performed. We verified the arterial origin of the bleeding and coagulated the bleeding focus. The histological diagnosis was aneurysmal artery. He recovered after surgery with mild disability. In a case of acute spontaneous SDH, the possibility of a cortical artery origin should be considered
Cognitive-Enhancing Effect of Aronia melanocarpa
Aronia melanocarpa (A. melanocarpa) berries are a fruit with a marked antioxidant effect. The objective of this study was to confirm the effect of A. melanocarpa berries extract against scopolamine-induced memory impairment in mice using the Morris water maze and passive avoidance test. Moreover, we determined a possible mechanism of the cognitive-enhancing effect involving AChE activity and BDNF and p-CREB expression in the hippocampus of mice. A. melanocarpa berries extract attenuated the learning and memory impairment induced by scopolamine in the Morris water maze (79.3 ± 0.8 s of 200 mg/kg and 64.4 ± 10.7 s of 400 mg/kg on day 4) and passive avoidance tests (46.0 ± 41.1 s of 200 mg/kg and 25.6 ± 18.7 s of 400 mg/kg). A. melanocarpa berries extract reduced the acetylcholinesterase level in the hippocampus of scopolamine-injected mice and increased BDNF and p-CREB expression in the hippocampus. The major compound, cyanidin-3-O-galactoside, also reversed memory impairment. These results showed that A. melanocarpa berries extract improved memory impairment by inhibiting AChE and increasing BDNF and p-CREB expression, and cyanidin-3-O-galactoside may be responsible for the effect of A. melanocarpa berries extract
Prospective Multi-Center Trial for the Efficacy of Ecabet Sodium on the Relief of Dyspepsia in Korean Patients with Chronic Gastritis
Anti-peptic and anti-inflammatory actions of ecabet sodium might be beneficial in either improving gastritis or relieving dyspeptic symptoms. This study was designed to evaluate the clinical efficacy of ecabet sodium on dyspeptic symptoms and to elucidate the molecular mechanism attributable to symptom relief in patients with chronic gastritis. Two hundred and sixty eight chronic gastritis patients with persistent dyspepsia received ecabet sodium 1 g b.i.d. for 2 weeks, after which dyspeptic symptoms were reassessed with a questionnaires as before. The changes of interleukin-8 (IL-8), inducible nitric oxide synthase (iNOS), prostaglandin E2 (PGE2), and vascular endothelial growth factor (VEGF) levels in gastric juices were measured by ELISA. The changes of nitrotyrosine in gastric mucosa were measured by immunohistochemical staining. The most common dyspeptic symptom in Korean patients with chronic gastritis was epigastric soreness (76.8%), which was improved significantly after ecabet sodium treatment (81.7%, p<0.001). Ecabet sodium was more effective in patients with epigastric pain than vague abdominal discomfort (p = 0.02), especially in patients with old age. Complete relief of discomfort was more highly achieved in patients with positive Helicobacter pylori than without (p = 0.01). In spite of clear tendency that the decreased levels of IL-8, iNOS, and PGE2 and increased levels of VEGF were measured in gastric juices after ecabet sodium treatment, no statistical significance was noted, which might be due to high inter-individual variations. The nitrotyrosine expressions were significantly decreased after ecabet sodium treatment than before (p<0.01). In conclusion, ecabet sodium treatment was very useful for the relief of dyspeptic symptoms in chronic gastritis, to which both attenuated inflammatory and enhanced regenerative mechanisms were contributive
Surface mass balance contributions to acceleration of Antarctic ice mass loss during 2003-2013
Recent observations from satellite gravimetry (the Gravity Recovery and Climate Experiment (GRACE) mission) suggest an acceleration of ice mass loss from the Antarctic Ice Sheet (AIS). The contribution of surface mass balance changes (due to variable precipitation) is compared with GRACE-derived mass loss acceleration by assessing the estimated contribution of snow mass from meteorological reanalysis data. We find that over much of the continent, the acceleration can be explained by precipitation anomalies. However, on the Antarctic Peninsula and other parts of West Antarctica, mass changes are not explained by precipitation and are likely associated with ice discharge rate increases. The total apparent GRACE acceleration over all of the AIS between 2003 and 2013 is −13.6 ± 7.2 Gt/yr^2. Of this total, we find that the surface mass balance component is −8.2 ± 2.0 Gt/yr^2. However, the GRACE estimate appears to contain errors arising from the atmospheric pressure fields used to remove air mass effects. The estimated acceleration error from this effect is about 9.8 ± 5.8 Gt/yr^2. Correcting for this yields an ice discharge acceleration of −15.1 ± 6.5 Gt/yr^2
- …