The Potential Adverse Reactions of Administering Combination Therapy in Covid-19 Patients

A definite treatment modality for coronavirus disease 2019 (COVID-19) has still not come into picture. With the rise of COVID-19 pandemic, a few drugs have come into light as empirical treatment for this infection. This review focusses on existing approaches to the treat COVID-19 patients with antimalarial drugs and antibiotics analyzing the adverse reactions and interactions of concomitantly administering these drugs. We will also discuss the possibilities of alternate methods to treat this disease

Predicted Performance Bounds of Thermochromism Assisted Photon Transport for Efficient Solar Thermal Energy Storage

Efficient storage of solar thermal energy is still one of the major bottlenecks in realizing dispatchable solar thermal systems. Present work is a significant step in this direction, wherein, we propose, thermochromism assisted photon transport based optical charging for efficient latent heat storage. Seeding thermochromic nanoparticles into the phase change material (PCM) allows for dynamic control of PCM's optical properties - aiding deeper penetration of photons and hence significantly enhancing the photon-nanoparticle interactions. Moreover, carefully tailoring of transition temperature near the melting temperature allows for efficient non-radiative decay of the absorbed photon energy and that too under nearly thermostatic conditions. In particular, the present work serves to develop a mechanistic opto-thermal theoretical modelling framework to compute melting front progression, latent heat storage and sensible heat discharging capacities pertinent to thermochromism assisted photon transport. Moreover, to truly assess and quantify the benefits of the aforementioned charging route, a host of other possible charging routes (viz., thermal and non-thermochromic optical charging) have also been dealt with. Detailed analysis reveals that relative to the thermal charging route, thermochromism assisted optical charging offers significant enhancements in terms of melting front progression (approximately 152%) and latent heat storage capacity (approximately 167%). Overall, thermochromism assisted photon transport is a synergistic approach which allows for simultaneous collection and storage of solar energy at accelerated rates without requiring the PCM to be heated to high temperatures.Comment: 28 pages, 17 figures, to be submitted to a Journa

Understanding Photo-thermal and Melting Mechanisms in Optical Charging of Nano and Micro Particles Laden Organic PCMs

The realm of latent heat storage has witnessed emergence of optical charging as a promising route of solar thermal latent heat storage. However, it is still in its initial stages of development and warrants further investigations to take it to the next level i.e., realization of optical charging based real-world systems. Engineering efficient optical charging process in turn necessitates efficient photo-thermal energy conversion, transfer as well as storage of the incident solar radiant energy. The present work is a determining step in deciphering, quantifying, and understanding the aforementioned steps involved in the optical charging process. In particular, experiments have been designed carefully to investigate optical charging of composite-PCMs (particles laden organic PCMs) with and without thermochromism assistance. Spatial-temporal temperature distribution curves reveal that temperature spread (in the liquid phase) in case of optical charging of non-thermochromic particles (carbon soot nanoparticles) laden PCMs is significantly high (as high as approximately 24 {\deg}C) relative to that observed in case of thermochromic particles (microcapsules) laden PCMs (approximately, 4 {\deg}C). The magnitude of the temperature spread (being representative of the deviation from thermostatic optical charging) clearly points out that opposed to non-thermochromic laden PCMs, nearly thermostatic optical charging can be achieved in case of thermochromic particles laden PCMs. Furthermore, in case of optical charging without thermochromic assistance, the temperature spread, peak temperatures and the melting rates increase with increase in particles concentration. Whereas, in the latter case, although the temperature spread and peak temperatures are nearly independent; the melting rates do depend on the particles concentration.Comment: 19 pages, 12 figures, to be submitted to a Journa