Multiphoton path entanglement by non-local bunching

Multiphoton path entanglement is created without applying post-selection, by manipulating the state of stimulated parametric down-conversion. A specific measurement on one of the two output spatial modes leads to the non-local bunching of the photons of the other mode, forming the desired multiphoton path entangled state. We present experimental results for the case of a heralded two-photon path entangled state and show how to extend this scheme to higher photon numbers.Comment: 4 pages, 5 figures, published versio

Serious Gaming for Water Systems Planning and Management

This is the final version of the article. Available from MDPI via the DOI in this record.Water systems planning and management share the same roots with gaming, as they rely on concepts in systems analysis, operations research and decision sciences. This paper focuses on Serious Games (those used for purposes other than mere entertainment), with applications in the area of water systems planning and management. A survey of published work on gaming is carried out with particular attention given to applications of Serious Gaming to water systems planning and management. The survey is also used to identify the principal criteria for the classification of Serious Gaming for water related applications, including application areas, goals, number and type of players, user interface, type of simulation model used, realism of the game, performance feedback, progress monitoring and game portability. The review shows that game applications in the water sector can be a valuable tool for making various stakeholders aware of the socio-techno-economic issues related to managing complex water systems. However, the critical review also indicates a gap that exists in the Serious Game application area with the lack of water distribution system games. A conceptually simple, but computationally elaborate new game for water distribution system analysis, design and evaluation (SeGWADE) is presented in this paper. It has a main goal of finding a least-cost design for a well-known benchmark problem, for which the game environment takes the computational and visualisation burden away from the simulation tool and the player. The game has been evaluated in a classroom environment in which a high degree of player engagement with the game was observed, due to its basic game ingredients and activities, i.e., challenge, play and fun. In addition, a clear improvement in learning has been observed in how players attempted to identify solutions that satisfy the pressure criterion with players readily identifying the proximity of the better solutions to the starting, infeasible configuration. Through applications of Serious Gaming such as this, decision makers can learn about the complexity of the water distribution system design problem, experiment safely using a computer model of a real system, understand conflicting objectives (i.e., minimization of cost and satisfaction of minimum pressure) and develop strategies for coping with complexity without being burdened by the limitations of the ICT technology at their disposal.The authors would like to acknowledge the funding provided by the UK Engineering and Physical Sciences Research Council, grant EP/M018865/1 (The Nexus Game)

Intake of Nutritional Supplements among People Exercising in Gyms in Beirut City

The use of nutritional supplements among exercisers in gyms has been never investigated in the Middle East. The aim of the current study was to assess the prevalence intake of nutritional supplements and the potential influencing factors among people exercising in gyms in Beirut city. In this cross-sectional study, 512 exercisers, aged between 20 and 50 years, were randomly selected from gyms. The intake of nutritional supplements was reported among 36.3% (95% confidence interval 32.2–40.5) of participants, with a weak presence of medical supervision. Patterns of supplement use differed by gender and age. Men and younger exercisers were found to focus on supplements associated with performance enhancement and muscle building, while women and older exercisers were more concerned with health-promoting products such as vitamins, minerals, and herbal supplements. An appropriate dissemination of accurate and scientifically sound information regarding the benefits and side effects of nutritional supplements is highly recommended in the sports environment in Beirut city

The cosmic gravitational wave background in a cyclic universe

Inflation predicts a primordial gravitational wave spectrum that is slightly ``red,'' i.e., nearly scale-invariant with slowly increasing power at longer wavelengths. In this paper, we compute both the amplitude and spectral form of the primordial tensor spectrum predicted by cyclic/ekpyrotic models. The spectrum is blue and exponentially suppressed compared to inflation on long wavelengths. The strongest observational constraint emerges from the requirement that the energy density in gravitational waves should not exceed around 10 per cent of the energy density at the time of nucleosynthesis.Comment: 4 pages, 3 figuer

Artificial Intelligence and Digital Microscopy Applications in Diagnostic Hematopathology

Digital Pathology is the process of converting histology glass slides to digital images using sophisticated computerized technology to facilitate acquisition, evaluation, storage, and portability of histologic information. By its nature, digitization of analog histology data renders it amenable to analysis using deep learning/artificial intelligence (DL/AI) techniques. The application of DL/AI to digital pathology data holds promise, even if the scope of use cases and regulatory framework for deploying such applications in the clinical environment remains in the early stages. Recent studies using whole-slide images and DL/AI to detect histologic abnormalities in general and cancer in particular have shown encouraging results. In this review, we focus on these emerging technologies intended for use in diagnostic hematology and the evaluation of lymphoproliferative diseases

Density Perturbations in the Ekpyrotic Scenario

We study the generation of density perturbations in the ekpyrotic scenario for the early universe, including gravitational backreaction. We expose interesting subtleties that apply to both inflationary and ekpyrotic models. Our analysis includes a detailed proposal of how the perturbations generated in a contracting phase may be matched across a `bounce' to those in an expanding hot big bang phase. For the physical conditions relevant to the ekpyrotic scenario, we re-obtain our earlier result of a nearly scale-invariant spectrum of energy density perturbations. We find that the perturbation amplitude is typically small, as desired to match observation.Comment: 36 pages, compressed and RevTex file, one postscript figure file. Minor typographical and numerical errors corrected, discussion added. This version to appear in Physical Review