Changing epidemiological trends of inflammatory bowel disease in Asia

Inflammatory bowel disease (IBD) has become more common in Asia over the past few decades. The rate of increase in prevalence of the disease varies greatly in Asia, with several countries in East Asia experiencing a more than doubled increase in IBD prevalence over the past decade. Historically, ulcerative colitis (UC) is more common than Crohn's disease (CD) in Asia. However, a reverse trend is beginning to appear in more developed countries in Asia such as Japan, Korea, and Hong Kong. While Asian IBD patients share many similarities with their Western counterparts, there are important differences with significant clinical implications. In Asia, there are more men with CD, more ileo-colonic involvement in CD, less familial aggregation, fewer extra-intestinal manifestations and worse clinical outcomes for older-onset patients with UC. These differences are likely related to the different genetic makeup and environmental exposures in different regions. Evaluation of the differences and rates in epidemiologic trends may help researchers and clinicians estimate disease burden and understand the reasons behind these differences, which may hold the key to unravel the etiology of IBD

Minimax mean estimator for the trine

We explore the question of state estimation for a qubit restricted to the $x$-$z$ plane of the Bloch sphere, with the trine measurement. In our earlier work [H. K. Ng and B.-G. Englert, eprint arXiv:1202.5136[quant-ph] (2012)], similarities between quantum tomography and the tomography of a classical die motivated us to apply a simple modification of the classical estimator for use in the quantum problem. This worked very well. In this article, we adapt a different aspect of the classical estimator to the quantum problem. In particular, we investigate the mean estimator, where the mean is taken with a weight function identical to that in the classical estimator but now with quantum constraints imposed. Among such mean estimators, we choose an optimal one with the smallest worst-case error-the minimax mean estimator-and compare its performance with that of other estimators. Despite the natural generalization of the classical approach, this minimax mean estimator does not work as well as one might expect from the analogous performance in the classical problem. While it outperforms the often-used maximum-likelihood estimator in having a smaller worst-case error, the advantage is not significant enough to justify the more complicated procedure required to construct it. The much simpler adapted estimator introduced in our earlier work is still more effective. Our previous work emphasized the similarities between classical and quantum state estimation; in contrast, this paper highlights how intuition gained from classical problems can sometimes fail in the quantum arena.Comment: 18 pages, 3 figure

Healthcare Worker Seroconversion in SARS Outbreak

Serum samples were obtained from healthcare workers 5 weeks after exposure to an outbreak of severe acute respiratory syndrome (SARS). A sensitive dot blot enzyme-linked immunosorbent assay, complemented by a specific neutralization test, shows that only persons in whom probable SARS was diagnosed had specific antibodies and suggests that subclinical SARS is not an important feature of the disease

Rank-based model selection for multiple ions quantum tomography

The statistical analysis of measurement data has become a key component of many quantum engineering experiments. As standard full state tomography becomes unfeasible for large dimensional quantum systems, one needs to exploit prior information and the "sparsity" properties of the experimental state in order to reduce the dimensionality of the estimation problem. In this paper we propose model selection as a general principle for finding the simplest, or most parsimonious explanation of the data, by fitting different models and choosing the estimator with the best trade-off between likelihood fit and model complexity. We apply two well established model selection methods -- the Akaike information criterion (AIC) and the Bayesian information criterion (BIC) -- to models consising of states of fixed rank and datasets such as are currently produced in multiple ions experiments. We test the performance of AIC and BIC on randomly chosen low rank states of 4 ions, and study the dependence of the selected rank with the number of measurement repetitions for one ion states. We then apply the methods to real data from a 4 ions experiment aimed at creating a Smolin state of rank 4. The two methods indicate that the optimal model for describing the data lies between ranks 6 and 9, and the Pearson $\chi^{2}$ test is applied to validate this conclusion. Additionally we find that the mean square error of the maximum likelihood estimator for pure states is close to that of the optimal over all possible measurements.Comment: 24 pages, 6 figures, 3 table

Women on boards of Malaysian firms: Impact on market and accounting performance

We seek to offer some reconciliation for the conflicting theoretical arguments and empirical findings regarding the impact of women’s participation in boards on firms’ performance.We suggest that this impact differs in relation to market- and accounting-performance, and it is firm-specific, and varies by firms’ ownership type and the composition of their boards.These arguments find theoretical underpinnings in agency and resource-dependency theories, combined with behavioral and discrimination theories that articulate women behavior in the workplace and market perception of gender equality.The empirical analysis is based on a dataset of 841 publicly-listed firms in Malaysia.The results show positive impact of women’s participation on accounting-performance and negative impact on market-performance, suggesting that women directors create economic value, which is undervalued by the market. We interpret the findings with reference to the perception of women’s role in society and business in Malaysia, and the nature of corporate governance and ownership types prevalent among Malaysian firms.We suggest that the relationships might be context-specific, and hence the desired level of women’s participation varies across countries.We discuss the normative implications of the findings for government authorities considering legislation of gender-quota on boards, and for firms

Raman transitions without adiabatic elimination: A simple and accurate treatment

10.1080/09500340.2013.770573Journal of Modern Optics604255-265JMOP

Using Prior Expansions for Prior-Data Conflict Checking

10.1214/20-BA1204Bayesian Analysis161203-23