Pengiraan Persentil Taburan Panjang Larian bagi Carta Kawalan Purata Bergerak Berpemberat Eksponen Multivariat

Prabhu dan Runger (1997) telah mengemukakan cadangan dalam pemilihan parameter-parameter untuk skema carta kawalan purata bergerak berpemberat eksponen multivariat (MEWMA). Walau bagaimanapun, cadangan tersebut hanya berdasarkan prestasi panjang larian purata (average run length - ARL). Oleh itu, dalam makalah ini, kami akan mengira nilai-nilai persentil untuk taburan panjang larian bagi pelbagai skema carta kawalan MEWMA yang dikemukakan oleh Prabhu dan Runger (1997). Persentil-persentil yang dikira akan membekalkan maklumat tambahan seperti kekerapan isyarat luar kawalan palsu yang awal (early false out of control signals), panjang larian median (median run length - MRL) dan kepencongan taburan panjang larian untuk sesuatu skema tertentu. Maklumat-maklumat tambahan ini mungkin berguna dalam membekalkan jurutera kawalan mutu pengetahuan mendalam dan lengkap tentang sesuatu skema carta kawalan MEWMA yang dipilih berdasarkan cadangan Prabhu dan Runger (1997)

Validation of the English and Chinese versions of the Quick-FLIC quality of life questionnaire.

A useful measure of quality of life should be easy and quick to complete. Recently, we reported the development and validation of a shortened Chinese version of the Functional Living Index-Cancer (FLIC), which we called the Quick-FLIC. In the present study of 327 English-speaking and 221 Chinese-speaking cancer patients, we validated the English version of the Quick-FLIC and further assessed the Chinese version. The 11 Quick-FLIC items were administered alongside the 11 remaining items of the full FLIC, but there appeared to be little context effect. Validity of the English version of the Quick-FLIC was attested by its strong correlation with two other measures of quality of life, and its ability to detect differences between patients with different performance status and treatment status (each P<0.001). Its internal consistency (alpha=0.86) and test-retest reliability (intraclass correlation=0.76) were also satisfactory. The measure was responsive to changes in performance status (P<0.001). The Chinese version showed similar characteristics. The Quick-FLIC behaved in ways that are highly comparable with the FLIC, even though the Quick-FLIC comprised only 11 items whereas the FLIC comprised 22. Further research is required to see whether the use of shorter instruments can improve data quality and response rates, but the fact that shorter instruments place less burden on the patients is itself inherently important

A Robust Exponentially Weighted Moving Average Control Chart for the Process Mean

To date, numerous extensions of the exponentially weighted moving average, EWMA charts have been made. A new robust EWMA chart for the process mean is proposed. It enables easier detection of outliers and increase sensitivity to other forms of out-of-control situation when outliers are present

DNA methylation of ESR-1 and N-33 in colorectal mucosa of patients with Ulcerative Colitis (UC)

Introduction: Epigenetic marking such as DNA methylation influence gene transcription and chromosomal stability and may also be affected by environmental exposures. Few studies exist on alteration in DNA methylation profiles (genomic and gene specific methylation) in patients with Ulcerative Colitis (UC) and none assessing its relationship with lifestyle exposures. Aims & Methods: To assess genomic methylation and promoter methylation of the ESR-1 (oestrogen receptor - 1) and N-33 (tumour suppressor candidate-3) genes in the macroscopically normal mucosa of UC patients as well as to investigate effects of anthropometric and lifestyle exposures on DNA methylation. Sixty eight subjects were recruited (24 UC and 44 age and sex matched controls). Colorectal mucosal biopsies were obtained and DNA was extracted. Genomic DNA methylation was quantified using the tritium-labelled cytosine extension assay (3[H] dCTP) whilst gene specific methylation was quantified using the COBRA method. Results: The methylation level of both ESR-1 and N-33 genes were significantly higher in UC subjects compared with controls (7.9% vs 5.9%; p = 0.015 and 66% vs 9.3%; p < 0.001 respectively). There was no detectable difference in global DNA methylation between patients with UC and age and sex matched controls. No associations between indices of DNA methylation and anthropometric measures or smoking patterns were detected. Conclusions: For the first time, we have shown increased methylation in the promoter regions of the putative tumour suppressor gene N-33 in macroscopically normal mucosa of patients with UC. In addition, we have confirmed that methylation of ESR-1 promoter is higher in UC patients compared with age and sex matched controls. These findings suggests that, inactivation through methylation of the putative tumour suppressor genes N-33 and ESR-1, may not be associated with colorectal carcinogenesis in UC

Optical supercavitation in soft-matter

We investigate theoretically, numerically and experimentally nonlinear optical waves in an absorbing out-of-equilibrium colloidal material at the gelification transition. At sufficiently high optical intensity, absorption is frustrated and light propagates into the medium. The process is mediated by the formation of a matter-shock wave due to optically induced thermodiffusion, and largely resembles the mechanism of hydrodynamical supercavitation, as it is accompanied by a dynamic phase-transition region between the beam and the absorbing material.Comment: 4 pages, 5 figures, revised version: corrected typos and reference

Time-dependent Nonlinear Optical Susceptibility of an Out-of-Equilibrium Soft Material

We investigate the time-dependent nonlinear optical absorption of a clay dispersion (Laponite) in organic dye (Rhodamine B) water solution displaying liquid-arrested state transition. Specifically, we determine the characteristic time $\tau_D$ of the nonlinear susceptibility build-up due as to the Soret effect. By comparing $\tau_D$ with the relaxation time provided by standard dynamic light scattering measurements we report on the decoupling of the two collective diffusion times at the two very different length scales during the aging of the out-of-equilibrium system. With this demonstration experiment we also show the potentiality of nonlinear optics measurements in the study of the late stage of arrest in soft materials

Signal processing by opto-optical interactions between self-localized and free propagating beams in liquid crystals

The reorientational nonlinearity of nematic liquid crystals enables a self-localized spatial soliton and its waveguide to be deflected or destroyed by a control beam propagating across the cell. We demonstrate a simple all-optical readdressing scheme by exploiting the lens-like perturbation induced by an external beam on both a nematicon and a co-polarized guided signal of different wavelength. Angular steering as large as 2.2 degrees was obtained for control powers as low as 32mW in the near infrared

Enhanced soliton interactions by inhomogeneous nonlocality and nonlinearity

We address the interactions between optical solitons in the system with longitudinally varying nonlocality degree and nonlinearity strength. We consider a physical model describing light propagation in nematic liquid crystals featuring a strongly nonlocal nonlinear response. We reveal that the variation of the nonlocality and nonlinearity along the propagation direction can substantially enhance or weaken the interaction between out-of-phase solitons. This phenomenon manifests itself as a slowdown or acceleration of the soliton collision dynamics in one-dimensional geometries or of the soliton spiraling rate in bulk media. Therefore, one finds that by engineering the nonlocality and nonlinearity variation rate one can control the output soliton location.Comment: 22 pages, 5 figures, to appear in Physical Review

Low-complexity transmit diversity scheme using moderate-sized signal constellations

In the conventional space-time coding technique [1], nT radio frequency (RF) chains are employed to transmit signals simultaneously from nT transmit antennas. In this Letter, a lowcomplexity transmit diversity scheme with nT = 2 transmit antennas is proposed. The proposed system employs only one RF chain as well as a low-complexity switch for transmission