7 research outputs found
Nutrition and lung cancer: a case control study in Iran
Background: Despite many prospective and retrospective studies about the association of dietary habit and lung
cancer, the topic still remains controversial. So, this study aims to investigate the association of lung cancer with
dietary factors.
Method: In this study 242 lung cancer patients and their 484 matched controls on age, sex, and place of residence
were enrolled between October 2002 to 2005. Trained physicians interviewed all participants with standardized
questionnaires. The middle and upper third consumer groups were compared to the lower third according to the
distribution in controls unless the linear trend was significant across exposure groups.
Result: Conditional logistic regression was used to evaluate the association with lung cancer. In a multivariate
analysis fruit (Ptrend < 0.0001), vegetable (P = 0.001) and sunflower oil (P = 0.006) remained as protective factors and
rice (P = 0.008), bread (Ptrend = 0.04), liver (P = 0.004), butter (Ptrend = 0.04), white cheese (Ptrend < 0.0001), beef
(Ptrend = 0.005), vegetable ghee (P < 0.0001) and, animal ghee (P = 0.015) remained as risk factors of lung cancer.
Generally, we found positive trend between consumption of beef (P = 0.002), bread (P < 0.0001), and dairy
products (P < 0.0001) with lung cancer. In contrast, only fruits were inversely related to lung cancer (P < 0.0001).
Conclusion: It seems that vegetables, fruits, and sunflower oil could be protective factors and bread, rice, beef,
liver, dairy products, vegetable ghee, and animal ghee found to be possible risk factors for the development of
lung cancer in Iran
Case Report - Generalized neutrophilic dermatosis: A rare presentation of myelodysplastic syndrome
We present a 30-year-old man admitted with generalized cutaneous
lesions, fever and cough. Examination of skin biopsies of a papular
lesion revealed dense neutrophilic infiltration of the upper dermis, so
these lesions were diagnosed as neutrophilic dermatosis. Peripheral
blood examination and bone marrow findings confirmed the diagnosis of
myelodysplastic syndrome with excess blasts. The cutaneous lesions
improved after administration of corticosteroid and follow-up bone
marrow examination revealed a normocellular marrow. One year later he
referred with acute myelogenous leukemia (AML-M0). Unfortunately, he
did not respond to treatment and died a few months later due to disease
progression
Generalized neutrophilic dermatosis: a rare presentation of myelodysplastic syndrome
We present a 30-year-old man admitted with generalized cutaneous
lesions, fever and cough. Examination of skin biopsies of a papular
lesion revealed dense neutrophilic infiltration of the upper dermis, so
these lesions were diagnosed as neutrophilic dermatosis. Peripheral
blood examination and bone marrow findings confirmed the diagnosis of
myelodysplastic syndrome with excess blasts. The cutaneous lesions
improved after administration of corticosteroid and follow-up bone
marrow examination revealed a normocellular marrow. One year later he
referred with acute myelogenous leukemia (AML-M0). Unfortunately, he
did not respond to treatment and died a few months later due to disease
progression
Primary anaplastic large cell lymphoma of trachea with subcutaneous emphysema and progressive dyspnea
Primary anaplastic large cell lymphoma of the trachea is a rare tumor. Common complaints are dyspnea and cough that could mimic a partially refractory asthma in some cases. We report a 16-year-old female with an anaplastic large cell lymphoma (null cell type) in which tracheal involvement was presented with life-threatening airway obstruction and subcutaneous emphysema. After debulking the tumor by endobronchial curettage, the patient was treated with chemotherapy followed by local radiotherapy. She had no evidence of local or distant recurrence after 25 months. Primary anaplastic large cell lymphoma of the trachea is a rare life-threatening disease. Nevertheless, this condition has a good prognosis if diagnosed immediately and treated with chemotherapy and radiotherapy
Nutrition and lung cancer: a case control study in Iran
Abstract
Background
Despite many prospective and retrospective studies about the association of dietary habit and lung cancer, the topic still remains controversial. So, this study aims to investigate the association of lung cancer with dietary factors.
Method
In this study 242 lung cancer patients and their 484 matched controls on age, sex, and place of residence were enrolled between October 2002 to 2005. Trained physicians interviewed all participants with standardized questionnaires. The middle and upper third consumer groups were compared to the lower third according to the distribution in controls unless the linear trend was significant across exposure groups.
Result
Conditional logistic regression was used to evaluate the association with lung cancer. In a multivariate analysis fruit (Ptrend < 0.0001), vegetable (P = 0.001) and sunflower oil (P = 0.006) remained as protective factors and rice (P = 0.008), bread (Ptrend = 0.04), liver (P = 0.004), butter (Ptrend = 0.04), white cheese (Ptrend < 0.0001), beef (Ptrend = 0.005), vegetable ghee (P < 0.0001) and, animal ghee (P = 0.015) remained as risk factors of lung cancer. Generally, we found positive trend between consumption of beef (P = 0.002), bread (P < 0.0001), and dairy products (P < 0.0001) with lung cancer. In contrast, only fruits were inversely related to lung cancer (P < 0.0001).
Conclusion
It seems that vegetables, fruits, and sunflower oil could be protective factors and bread, rice, beef, liver, dairy products, vegetable ghee, and animal ghee found to be possible risk factors for the development of lung cancer in Iran