Применение информационных технологий и этические нюансы в управлении массовым сознанием

This paper discusses the current value of information technology in our lives, as well as their application to control the mass consciousness

Real-Time Visualization and Quantitation of Vascular Permeability In Vivo: Implications for Drug Delivery

The leaky, heterogeneous vasculature of human tumors prevents the even distribution of systemic drugs within cancer tissues. However, techniques for studying vascular delivery systems in vivo often require complex mammalian models and time-consuming, surgical protocols. The developing chicken embryo is a well-established model for human cancer that is easily accessible for tumor imaging. To assess this model for the in vivo analysis of tumor permeability, human tumors were grown on the chorioallantoic membrane (CAM), a thin vascular membrane which overlays the growing chick embryo. The real-time movement of small fluorescent dextrans through the tumor vasculature and surrounding tissues were used to measure vascular leak within tumor xenografts. Dextran extravasation within tumor sites was selectively enhanced an interleukin-2 (IL-2) peptide fragment or vascular endothelial growth factor (VEGF). VEGF treatment increased vascular leak in the tumor core relative to surrounding normal tissue and increased doxorubicin uptake in human tumor xenografts. This new system easily visualizes vascular permeability changes in vivo and suggests that vascular permeability may be manipulated to improve chemotherapeutic targeting to tumors

The contribution of virtual production intelligence to laser cutting planning processes

In order to facilitate the improvement in product quality and production efficiency, many companies use simulation applications. In turn, they face the challenge of making these applications interoperable. Once the interoperability is established, the challenges of understanding and improving the processes arise. They can be overcome by modeling and analyzing the processes in question. This paper presents a use case scenario from laser cutting. A new concept is introduced addressing the challenges aforementioned. It conforms to the principles of the integration and examination of data and combines virtual production with the goal of gaining knowledge through the analysis of simulated processes

Virtual production intelligence (VPI)

The research area Virtual Production Intelligence (VPI) focuses on the integrated support of collaborative planning processes for production systems and products. The focus of the research is on processes for information processing in the design domains Factory and Machine. These processes provide the integration and interactive analysis of emerging, mostly heterogeneous planning information. The demonstrators (flapAssist, memoSlice und VPI platform) that are information systems serve for the validation of the scientific approaches and aim to realize a continuous and consistent information management in terms of the Digital Factory. Central challenges are the semantic information integration (e.g., by means of metamodeling), the subsequent evaluation as well as the visualization of planning information (e.g., by means of Visual Analytics and Virtual Reality). All scientific and technical work is done within an interdisciplinary team composed of engineers, computer scientists and physicists