EVALUATING THE USE OF A SPECIALISED TECHNOLOGICAL APPLICATION ON STUDENTS LEARNING GROWTH

From experience, students usually drop in their achievement levels only when faced with a situation that is beyond their control. Situations that impact them are either physical, mental, or both, such as bullying, family sickness, or death. The global pandemic that swept the world was a situation that has globally affected all human beings. This impact was substantial not just from a humanistic perspective of well-being but also economically and academically. The economic and human impact was an experience that could be seen directly within the schools of Qatar. Large swathes of children were showing lower academic levels than was predicted before the pandemic. When we returned from Covid, levels of learning were below what teachers expected. Globally, government and school expectations were for children to catch up. In Qatar, this was also the expectation. Schools behaved in such a way that they required children to continue as if they had not missed a second of education. Experience and observation showed differently

EVALUATING THE USE OF A SPECIALISED TECHNOLOGICAL APPLICATION ON STUDENTS LEARNING GROWTH

From experience, students usually drop in their achievement levels only when faced with a situation that is beyond their control. Situations that impact them are either physical, mental, or both, such as bullying, family sickness, or death. The global pandemic that swept the world was a situation that has globally affected all human beings. This impact was substantial not just from a humanistic perspective of well-being but also economically and academically. The economic and human impact was an experience that could be seen directly within the schools of Qatar. Large swathes of children were showing lower academic levels than was predicted before the pandemic. When we returned from Covid, levels of learning were below what teachers expected. Globally, government and school expectations were for children to catch up. In Qatar, this was also the expectation. Schools behaved in such a way that they required children to continue as if they had not missed a second of education. Experience and observation showed differently

EVALUATING THE USE OF A SPECIALISED TECHNOLOGICAL APPLICATION ON STUDENTS LEARNING GROWTH

From experience, students usually drop their achievement levels only when faced with a situation beyond their control. Situations that impact them are physical, mental, or both, such as bullying, family sickness, or death. The global pandemic that swept the world was a situation that has globally affected all human beings. This impact was substantial from a humanistic well-being perspective and economically and academically. The economic and human impact was an experience that could be seen directly within the schools of Qatar. Large swathes of children showed lower academic levels than predicted before the pandemic. When we returned from Covid, levels of learning were below what teachers expected. Globally, government and school expectations were for children to catch up. In Qatar, this was also the expectation. Schools behaved in such a way that they required children to continue as if they had not missed a second of education. Experience and observation showed differently

Evaluation of anakinra in the management of patients with COVID-19 infection: A randomized clinical trial

Background: The global COVID-19 pandemic led to substantial clinical and economic outcomes with catastrophic consequences. While the majority of cases has mild to moderate disease, minority of patients progress into severe disease secondary to the stimulation of the immune response. The hyperinflammatory state contributes towards progression into multi-organ failure which necessitates suppressive therapy with variable outcomes. This study aims to explore the safety and efficacy of anakinra in COVID-19 patients with severe disease leading to cytokine release syndromes. Methods: In this open-label, multi-center, randomized clinical trial, patients with confirmed COVID-19 infection with evidence of respiratory distress and signs of cytokine release syndrome were randomized in 1:1 ratio to receive either standard of care (SOC) or anakinra (100 mg subcutaneously every 12 h for 3 days then 100 mg subcutaneously once daily for 4 days) in addition to SOC. The primary outcome was treatment success at day 14 as defined by the WHO clinical progression score of ≤3. Primary analysis was based upon intention-to-treat population, with value of p of <0.05. Results: Out 327 patients screened for eligibility, 80 patients were recruited for the study. The mean age was 49.9 years (SD = 11.7), with male predominance at 82.5% (n = 66). The primary outcome was not statistically different (87.5% (n = 35) in anakinra group vs. 92.5% (n = 37) in SOC group, p = 0.712; OR = 1.762 (95%CI: 0.39–7.93). The majority of reported adverse events were mild in severity and not related to the study treatment. Elevated aspartate aminotransferase was the only significant adverse event which was not associated with discontinuation of therapy. Conclusion: In patients with severe COVID-19 infection, the addition of anakinra to SOC treatment was safe but was not associated with significant improvement according to the WHO clinical progression scale. Further studies are warranted to explore patients’ subgroups characteristics that might benefit from administered therapy. Clinical Trial Registration: Trial registration at ClinicalTrials.gov, identifier: NCT04643678.This study was funded by the Medical Research Center at Hamad Medical Corporation, Qatar (MRC-01-20-1095)

Statistical analysis of electromagnetic field inside a jet engine using the reverberation chamber approach

In this paper, the electromagnetic field distribution inside a jet engine is studied through full wave analysis. Results are statistically analyzed by comparisons to the models used for the reverberation chamber with a mechanical mode stirrer. The jet engine is simulated as an open cylinder containing one set of rotating blades by using 'Ansys HFSS'. A simple Hertzian dipole illuminates the interior structure as an incident wave excitation representing a transmitting antenna radiating continuous wave fields. The field distribution inside the engine, which results from a distinct set of rotating positions of the blades, is primarily studied through the simulation program. In our case, the mechanical stirrer is represented by the rotating set of blades. The field values are extracted at different planes along the cylindrical engine, and the average field is statistically analyzed. We show that the squared magnitude of the field component along the engine's main axis has an exponential distribution compared to the theoretical exponential distribution proved in a reverberation chamber. This approach promises to act as a novel effective method to analyze the engine system without dealing with the complex details inside the engine cavity.Scopus2-s2.0-8486021206

Swinging with the Jet Set: Analysis of Electromagnetic Fields Inside Jet Engines - From Numerical and Experimental Analysis to Statistical Analysis

Analyzing electromagnetic propagation inside jet engine turbines is a challenging and important research topic due to its potential applications in both civil and military fields. Electromagnetic modeling of such complex cavities is very difficult due to their complex geometry and the harsh surrounding environment, as well as the rotating metallic parts they contain. In addition, it is extremely difficult to extract the field values from arbitrarily shaped model geometries having large sizes, complex terminations, and cross-section variations.Scopu

COL2A1 and Caspase-3 as Promising Biomarkers for Osteoarthritis Prognosis in an Equus asinus Model

Osteoarthritis (OA) is one of the most degenerative joint diseases in both human and veterinary medicine. The objective of the present study was the early diagnosis of OA in donkeys using a reliable grading of the disease based on clinical, chemical, and molecular alterations. OA was induced by intra-articular injection of 25 mg monoiodoacetate (MIA) as a single dose into the left radiocarpal joint of nine donkeys. Animals were clinically evaluated through the assessment of lameness score, radiographic, and ultrasonographic findings for seven months. Synovial fluid and cartilage samples were collected from both normal and diseased joints for the assessment of matrix metalloproteinases (MMPs) activity, COL2A1 protein expression level, and histopathological and immunohistochemical analysis of Caspase-3. Animals showed the highest lameness score post-induction after one week then decreased gradually with the progression of radiographical and ultrasonographic changes. MMP activity and COL2A1 and Caspase-3 expression increased, accompanied by articular cartilage degeneration and loss of proteoglycan. OA was successfully graded in Egyptian donkeys, with the promising use of COL2A1and Caspase-3 for prognosis. However, MMPs failed to discriminate between early and late grades of OA