Comparison of Thin-Prep and cell block preparation for the evaluation of Thyroid epithelial lesions on fine needle aspiration biopsy

Abstract Background The objective of this study was to compare the utility of Thin-Prep (TP) cytologic preparation with that of Cell Block (CB) preparation in the diagnosis of thyroid lesions, mainly follicular epithelial lesions, by fine needle aspiration biopsy (FNAB). Feasibility of using the TP slides for immunocytochemical stains is also discussed. Methods A total of 126 consecutive cases of thyroid FNAB with TP slides and 128 consecutive cases of thyroid FNAB with CB slides were reviewed blindly by two cytopathologists. The presence of colloid, follicular cells, macrophages and lymphocytes/plasma cells were recorded and scored 0–4 on each case based on TP or CB slide review. The cytologic diagnoses were grouped as follows: cyst, colloid nodule, colloid nodule with cystic change, chronic thyroiditis, atypical/neoplastic and non-diagnostic. Results The TP slides had higher diagnostic rate than CB slides. The diagnostic yield was 68% of the TP slides whereas only 24% of the CB slides were diagnostic. Also, only 4 atypical/neoplastic lesions were diagnosed on the TP slides and the corresponding direct smears, while 5 cases of atypical/neoplastic lesions were diagnosed on the smears but could not be diagnosed on the corresponding CB slides. Additionally, the TP slides revealed cytologic features that were not observed on the direct traditional smears of the same case. Conclusion In thyroid FNAB cases, TP slide preparation is superior to CB slide preparation and is more likely to have greater cellularity for diagnosis and detect atypical/neoplastic thyroid lesions, particularly those of follicular cell origin. Furthermore, TP slides appear to detect helpful diagnostic cytologic features and should be considered complementary to, rather than replacing, direct smears

Preparation and Physical Properties of Functional Barium Carbonate Nanostructures by a Facile Composite-Hydroxide-Mediated Route

In recent years, nanotechnology has given birth to numerous nanomaterials due to their increased use in various sectors of research and development. To produce these nanomaterials, nanotechnology further has opened several rooms for the potential novel methods. Composite-hydroxide-mediated (CHM) method is one of the recent chemical synthesis routes that have gained considerable importance in research due to their effortlessness and versatile nature, covering a broad range of nanomaterials to prepare

Board diversity and financial reporting quality: evidence from China

This study explores the relationship between board diversity and financial reporting quality (FRQ) in China, an emerging market, by using panel data techniques. Specifically, it investigates firms registered from 2005 to 2018. Board diversity is categorised into relation (i.e., gender and age), task (i.e., education, tenure, and experience), and overall board diversity (sum of relation and task diversities). Findings indicate that board diversity has a significant positive impact on FRQ. The relationship between board diversity and FRQ is also strong in non-stateowned firms and during noncrisis periods. Findings remain consistent after numerous robustness checks comprising instrumental approach, propensity score matching, generalised method of moment, lag of independent variables, Heckman two-step model, change analysis, and alternative FRQ measures. Overall, board diversity is found to be associated with corporate outcomes

Mixed convection flow of water conveying graphene oxide nanoparticles over a vertical plate experiencing the impacts of thermal radiation

Water has drawn a lot of interest as a manufacturing lubricant since it is affordable, eco-friendly, and effective. Due to their exceptional mechanical qualities, water solubility, and variety of application scenarios, graphene oxide (GO)-based materials have the potential to increase the lubricant performance of water. The idea of this research was to quantify the linear 3D radiative stagnation-point flow induced by nanofluid through a vertical plate with a buoyancy or a mixed convection effect. The opposing, as well as the assisting, flows were considered in the model. The leading partial differential equations (PDEs) were transformed into dimensionless similarity equations, which were then solved numerically via a bvp4c solver. The influences of various physical constraints on the fluid flow and thermal properties of the nanofluid were investigated and are discussed. Water-based graphene oxide nanoparticles were considered in this study. The numerical outcomes indicated that multiple solutions were obtained in the case of the opposing flow (λ < 0). The critical values increased as the nanoparticle volume fraction became stronger. Furthermore, as the nanoparticles increased in strength, the friction factor increased and the heat transfer quickened. The radiation factor escalated the heat transfer in both solutions. In addition, a temporal stability analysis was also undertaken to verify the results, and it was observed that the branch of the first outcome became physically reliable (stable) whilst the branch of the second outcome became unstable, as time passed

MHD mixed convection hybrid nanofluids flow over a permeable moving inclined flat plate in the presence of thermophoretic and radiative heat flux effects

Recent nanotech advancements have created a tremendous platform for the development of a superior ultrahigh performance coolant referred to as nanofluid for several industrial and engineering technologies. In this research, the impact of thermophoretic and viscous dissipation on the radiative mixed convective flow comprising hybrid nanofluid through an inclined permeable moving flat plate with a magnetic field is examined numerically. A model of non-linear differential equations is derived based on some realistic assumptions and tackled numerically using the bvp4c technique. The impact of the specific set of distinguished parameters on the velocity profiles, shear stress, temperature distribution profiles, heat transfer, concentration distribution profile, and mass transfer for the two dissimilar branch solutions are discussed in detail. In addition, it has been discovered that double solutions exist in the case of an opposing flow, while a single solution is observed in the case of an assisting flow. The temperature distribution profile escalates with the radiation parameter, while decelerating the velocity and concentration profiles

Time-dependent flow of water-based CoFe2O4-Mn-ZnFe2O4 nanoparticles over a shrinking sheet with mass transfer effect in porous media

The use of hybrid nanoparticles to increase heat transfer is a favorable area of research, and therefore, numerous scientists, researchers, and scholars have expressed their appreciation for and interest in this field. Determining the dynamic role of nanofluids in the cooling of microscopic electronic gadgets, such as microchips and related devices, is also one of the fundamental tasks. With such interesting and useful applications of hybrid nanofluids in mind, the main objective is to deal with the analysis of the unsteady flow towards a shrinking sheet in a water-based hybrid ferrite nanoparticle in porous media, with heat sink/source effects. Moreover, the impact of these parameters on heat and mass transfers is also reported. Numerical results are obtained using MATLAB software. Non-unique solutions are determined for a certain shrinking strength, in addition to the unsteadiness parameter. The mass transfer and friction factor increase for the first solution due to the hybrid nanoparticles, but the heat transfer rate shows the opposite effect

Analytical approach for a heat transfer process through nanofluid over an irregular porous radially moving sheet by employing KKL correlation with magnetic and radiation effects: applications to thermal system

The aluminum nanoparticle is adequate for power grid wiring, such as the distribution of local power and the transmission of aerial power lines, because of its higher conductivity. This nanoparticle is also one of the most commonly used materials in applications in the electrical field. Thus, in this study, a radiative axisymmetric flow of Casson fluid, induced by water-based Al2O3 nanofluid by using the Koo–Kleinstreuer–Li (KKL) correlation, is investigated. The impact of the magnetic field is also taken into account. KKL correlation is utilized to compute the thermal conductivity and effective viscosity. Analytical double solutions are presented for the considered axisymmetric flow model after implementing the similarity technique to transmute the leading equations into ordinary differential equations. The obtained analytic forms were used to examine and discuss the velocity profile, the temperature distribution, reduced heat transfer, and coefficient of reduced skin friction. The analytic solutions indicate that the velocity profile decreases in the branch of the first solution and uplifts in the branch of the second solution due to the presence of an aluminum particle, whereas the dimensionless temperature enhances in both solutions. In addition, the Casson parameter increases the friction factor, as well as the heat transport rate

Analysis of jet wall flow and heat transfer conveying ZnO-SAE50 nano lubricants saturated in Darcy-Brinkman porous medium

The problem of 2D (two-dimensional) wall jet flow, along with heat transfer incorporated by nanofluid in a Darcy-Brinkman medium, while recognizing the requirement for efficient heating and cooling systems. Following the use of similarity variables, the resultant system of ODEs (ordinary differential equations) is solved using the well-known and efficient bvp4c (boundary-value problem of the 4th order) technique. The significance of physical quantities for the under-consideration parameters is illustrated and explained. The findings show that the nanoparticle volume fraction and porosity parameters decrease the velocity, but increase the temperature. In addition, the temperature uplifts in the presence of radiation effect. The suction parameter initially decreases and then increases the velocity near the surface, while the temperature declines

Impact of buoyancy and stagnation-point flow of water conveying Ag-MgO hybrid nanoparticles in a vertical contracting/expanding Riga wedge

Riga surface can be utilized to reduce the pressure drag and the friction of the submarine by stopping the separation of the boundary layer as well as by moderating turbulence production. Therefore, the current symmetry of the work investigates the slip impacts on mixed convection flow containing water-based hybrid Ag-MgO nanoparticles over a vertical expanding/contracting Riga wedge. In this analysis, a flat surface, wedge, and stagnation point are also discussed. A Riga surface is an actuator that contains electromagnetic where a span-wise array associated with the permanent magnets and irregular electrodes accumulated on a smooth surface. A Lorentz force is incorporated parallel to the surface produced by this array which eases exponentially normal to the surface. Based on the considered flow symmetry, the physical scenario is initially modeled in the appearance of partial differential equations which are then rehabilitated into a system of ordinary differential equations by utilizing the pertinent similarity variables. A bvp4c solver is engaged to acquire the numerical solution. The flow symmetry and the influences of pertaining parameters involved in the problem are investigated and are enclosed in graphical form. The findings confirm that the velocity reduces, and temperature enhances due to nanoparticle volume fraction. A modified Hartmann number increases the velocity and diminishes the temperature. Moreover, the suction parameter enhances the velocity profiles and reduces the dimensionless temperature profiles. The heat transfer gradually increases by diminishing the contracting parameter and increasing the expanding parameter