25 research outputs found
Perancangan Database Sistem Informasi Akuntansi Penjualan di Ud. Niwatori
The purpose of this research is to understand of data processing and also to design database accounting information system of sales cycle of UD. Niwatori. The company is located in Kuta Malaka, Aceh Besar, which is engaged on business of livestock and eggs. Nowadays, UD. Niwatori uses manual system in running the business. This situation makes UD. Niwatori difficult in producing information in detail, especially in the sales cycle. In this study, data used is primary data in the form of interviews with parties involved in the sales cycle and secondary data in the form of documents used in the sales cycle. The result of this research is the applicable database management system of sales cycl
A rapid and facile synthesis of isoxazolyl and pyrazolyl phenols from enaminoketones using montmorillonite under heterogeneous catalytic conditions
1295-1297A number of isoxazolyl and
pyrazolyl phenols (4a-f and 5a-d) have been
synthesized from 1-(2-hydroxyaryl)-3-dimethylamino-2-propen-1-ones 3a-f
using montmorillonite as solid acid support
Spina bifida occulta in isthmic spondylolisthesis: a surgical trap
An 11-year-old girl presented with symptomatic grade IIB isthmic type spondylolisthesis, with an elongated pars, confirmed on magnetic resonance imaging (MRI). Posterolateral in situ fusion of L5/S1 was performed. At surgery, a significant bony defect in the posterior aspect of S1 was noted. Awareness of this possible co-existence is paramount if iatrogenic damage to neural elements is to be avoided during surgery
Synthesis and Anti-Cancer Activity of New Pyrazolinyl-Indole Derivatives: Pharmacophoric Interactions and Docking Studies for Identifying New EGFR Inhibitors
Newly designed series of indole-containing pyrazole analogs, pyrazolinylindoles, were synthesized, and their structures were confirmed based on the spectral data of the 1H NMR, 13C NMR, and HR-MS analyses. Preliminary anti-cancer activity testings were carried out by the National Cancer Institute, United States of America (NCI, USA). Compounds HD02, HD05, and HD12 demonstrated remarkable cytotoxic activities against nine categories of cancer types based cell line panels which included leukemia, colon, breast, melanoma, lungs, renal, prostate, CNS, and ovarian cancer cell lines. The highest cytotoxic effects were exhibited by the compounds HD02 [1-(5-(1-H-indol-3-yl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)-2-phenylethanone], HD05 [1-(3-(4-chlorophenyl)-5-(1H-indol-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)-2-phenoxyethanone], and HD12 [(3-(4-chlorophenyl)-5-(1H-indol-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)(pyridin-4-yl)methanone] against some of the 56 types of NCI-based cell lines in different panels. Compound HD05 showed the maximum range of cancer cell growth inhibitions against all categories of the cell lines in all nine panels. On average, in comparison to the referral standard, imatinib, at a dose level of 10 µM, the HD05 showed significant activity against leukemia in the range of 78.76%, as compared to the imatinib at 9% of cancer cells’ growth inhibitions. Molecular docking simulation studies were performed in silico on the epidermal growth factor receptor (EGFR) tyrosine kinase, in order to validate the activity
Prevalence of Carotid Artery Stenosis in Patients Undergoing Coronary Artery Bypass Grafting: A Single-Centre Study in Bangladesh
Mymensingh medical journal : MMJ3241015-1021Banglades