Conception optimale d'un alternateur de faible puissance pour le simulateur de groupe turbine-alternateur d'Hydro-Québec

Dans le présent mémoire, un outil de conception optimale est développé puis utilisé pour la conception d'un alternateur de faible puissance faisant partie d'un simulateur analogique de groupe turbine/alternateur. L'outil de conception inclut une étape de validation, par la méthode des éléments finis, des performances aussi bien en régime permanent que dynamique du concept élaboré. Une revue de littérature complète est d'abord présentée avant de passer à une discussion théorique sur les notions fondamentales relatives au calcul électromagnétique. Une méthodologie de conception, basée sur un modèle analytique est développée pour les besoins de ce travail. Dans ce modèle analytique, les paramètres du circuit équivalent en régime permanent et le rendement de la machine sont calculés à partir des caractéristiques dimensionnelles et structurales de la machine. Le modèle analytique est ensuite intégré dans un processus d'optimisation multi-objets par algorithme génétique dont on a entrepris l'étude complète. L'outil d'analyse par éléments finis est tout d'abord programmé sous ANSYS puis appliqué à l' étude d'une génératrice synchrone de 120V A de la marque Lab-Volt disponible aux laboratoires de l'UQAT. La validité de cet outil est vérifiée par une très bonne concordance entre les résultats expérimentaux et numériques. Par la suite, l'outil de conception optimale est programmé sous Maltab® puis utilisé pour l'optimisation du rendement et de la masse de l'alternateur du simulateur. Un ensemble de solutions d'optimalité équivalente est dégagé et la solution à plus haut rendement est retenue comme concept final. Ce concept est ensuite validé par des analyses par éléments finis en régime permanent et dynamique et certains résultats sont comparés aux données du modèle analytique. La marge d'erreur à ce niveau s'avère tout à fait acceptable

Article Review: Biochemical Aspect of Survivin Hormone

A cancer gene called survivin is muted in cells which have undergone differentiation, but it is highly qualitative sample in the overwhelming proportion of malignancies. Over subsequent decades, there has been a lot of curiosity in it. Inhibiting apoptotic, encouraging mitotic, and increasing vascular formation while producing cytotoxic drugs are several crucial characteristics that define it is a good target. These processes, that together promote carcinogenic behaviour, cover the whole spectrum of carcinogenesis, encompassing growth, migratory, or infiltration. Survivin identification independently or coupled in blood and/or urine has become a diagnostic tool for prostate cancer. Furthermore, a number of researches showed that abnormal survivin transcription is linked to a poor prognosis or radiation/drug resistance. Early findings from approaches that target survivin in the treatment of breast carcinoma are encouraging. In order to clarify how this intriguing chemical performs such contradictory function, researchers outline its involvement in the detection, prognosis, as well as therapy of melanoma in this review. The IAP enzyme group, which includes the survival protein (SVN), stimulates cell growth or prevents apoptosis. As a biomarker for autoimmune conditions, hyper plasia, or malignancies, accumulation of Survivin is linked to these conditions. Increasingly acknowledged like a tumor-associated antigen (TAA), SVN has emerged as a crucial focus for the detection or management of malignancy

Spontaneous triplet pregnancy with twin fetuses papyraeci: a rare case report and review of the literature

A fetal death in a multiple pregnancy with one or more normally surviving fetus is unusual. Fetus papyraceous (FP) is a rare obstetric complication in multiple gestations. It is defined as retention of a mummified parchment like remains of a dead fetus in multiple pregnancy associated with a viable twin. It is important to reassure the patient of the normal outcome expected in most of the cases. Herein, we report a rare case of twin FP in a spontaneous triplet pregnancy with a literature review of maternal and neonatal outcomes and management of similar cases

Synthesis and thermodynamics of the reactions of [Pd(Eten)(H2O)2]2+ with ligands of biological significane with reference to the antitumour activity

Pd(Eten)Cl2  complex, where Eten = N-ethylethylenediamine , was synthesized and characterized by elemental analysis and spectroscopic techniques. The stoichiometry and stability of the complexes formed between [Pd(Eten)(H2O)2]2+ and various biologically relevant ligands  as adenine, adenosine, adenosine-5’-monophosphate  and some selected peptides  were investigated at 25ºC and 0.1 M ionic strength. The speciation diagrams of the complexes formed in solutions are evaluated. Thermodynamic parameters for Pd(Eten)-glycylglycine complexes were estimated

Heavy Metal Pollution and Men Infertility in Al-Falluja City

Infertilityis oneuof the most problemsathatufacingaadvancedunations. In the general, about halfof allacasesaof the infertility are causedby factors thaturelated toathe male partner. Propos educausesvofumalev infertility include evgeneticuand environmental factors. Blood samples from 64 infertileumen allawere living in urban its al-Fallujah city (30 azospermeiauand 34 oligospermeia) and 32 fertile men (asuthe control group) were collected. Heavy metal concentrations inusera of infertile and fertile groupswereumeasured by using Atomic Absorption Spectrophotometer. Y- chromosomemicrodeletions were detected by using PCR techniques. Significantdifferences (P?0.05)uin the concentration ofucopper (0.0267±0.0147 and 0.0278±0.0273, for infertileuand fertile group respectively), cadmium (0.0477± 0.0038 and 0.0446±0.0059, respectively) and zinc (1.08 ± 0.16) in fertile groupamoreover wereadetected, no deletionsawere recorded in Y Chromosome in peopleuwho exposed to heavy metals in each a azospermiavor severe oligospermia groups. Spermatogenesis disruption in theamale at any phase of cell differentiationamay be increased the abnormaluof sperm count also decrease theutotalspermucount, impair the stability of sperm chromatinuordamageain the sperm DNA

Assessment of Circulating Anti-Müllerian Hormone in Women Using Hormonal Contraception: A Systematic Review

Background: The status of ovarian reserve markers during hormonal contraception (HC) remains uncertain with conflicting literature data. The purpose of this study was to assess the impact of HC on circulating anti-Müllerian hormone (AMH) and other ovarian reserve markers.Materials and Methods: A systematic review was conducted, including all cohort, cross-sectional, and randomized controlled studies assessing serum anti Müllerian hormone concentration in women using HC. Data sources included MEDLINE, EMBASE, DynaMed Plus, ScienceDirect, TRIP database, ClinicalTrials.gov, and the Cochrane Library from January 2000 to October 2018.Results: A total of 366 studies were identified, of which 15 were eligible, including 3280 women, mostly using combined HC (CHC). Articles were divided according to duration of HC into short- (2–3 weeks), medium- (2–6 months), long- (>1 year), and varied-term studies. Two study designs were identified, including studies comparing AMH before and during/after CHC and studies comparing CHC users versus nonusers. Short- and medium-term studies (n = 284) reported no change in circulating AMH in women using cyclical CHC for one to six cycles. Apart from one study, all long- and varied-term studies (six studies, n = 1601) consistently showed a marked decline in AMH, antral follicle count, and ovarian volume. Three long-term studies (n = 1324) provided evidence of AMH recovery after discontinuation of HC.Conclusion: Circulating AMH seems to remain unchanged in women using cyclical CHC for up to 6 months, but appears to markedly decline in long-term users with recovery after discontinuation