Mouth exposure to carbohydrate prior to exercise possibly impairs the efficacy of carbohydrate mouth rinsing during exercise

Decker K. P., M. J. Saunders, N. D. Luden, C. J. Womack, and N. J. Hladick. Mouth Exposure to Carbohydrate Prior to Exercise Possibly Impairs the Efficacy of Carbohydrate Mouth Rinsing during Exercise. Purpose: Carbohydrate mouth-rinsing (CHO-MR) during intense endurance exercise has been associated with improved cycling performance, due to neurological influences. However, prior studies have reported the efficacy of CHO-MR is attenuated following a pre-exercise meal. To determine if this outcome is related to desensitization of CHO receptors (rather than metabolic effects following digestion), this study will investigate whether CHO-MR prior to exercise influences cycling performance when CHO-MR is also used during exercise. Methods: Eight trained cyclists (age, 24 ± 6 yr; height, 176 ± 6 cm; weight 75 ± 12 kg; VO2max, 61 ± 8 ml/kg/min) completed three exercise trials, each consisting of 15-min of incremental, constant-load exercise followed by a simulated 30-km time-trial (TT). Treatment beverages in the trials were randomly counterbalanced: a) PL_PL: placebo before and during exercise, b) PL_CHO: placebo pre-exercise, CHO-MR during exercise, and c) R_CHO: CHO-MR before and during exercise. Physiological responses (VO2, VE, RER, RPE, heart rate, blood glucose and lactate) were assessed during constant-load exercise and during the TT. Magnitude-based qualitative inferences were used to evaluate differences in responses between treatments. Results: TT performance was ‘possibly’ impaired (59% likelihood) with R_CHO (57.3 ± 3.6) versus PL_CHO (56.9 ± 3.0 min). Both trials were ‘likely’ slower than PL_PL (55.8 ± 3.1 min), but the reliability of performance data from this trial may have been impacted by measurement error, which limited our ability to determine the influence of CHO-MR during exercise. Physiological responses between treatments during constant-load cycling, and the TT were generally similar between all treatments. Conclusion: A pre-exercise CHO-MR had a possibly negative impact on cycling performance that also included CHO-MR during exercise. Although further evidence is required to validate this finding, our data suggests that desensitization of CHO receptors related to recent CHO exposure may be partially responsible for previous reports that the efficacy of CHO-MR during exercise are attenuated by pre-exercise feedings. Keywords: CYCLING, CARBOHYDRATE, MOUTH-RINSING, PERFORMANCE, ERGOGENIC-AIDS

Allocating Power: Toward a New Federalism Balance for Electricity Transmission Siting

Expansion and improvement of the nation’s electricity transmission system are crucial for increasing the amount of electricity generated by renewable energy sources. Renewable energy sources, such as wind and tidal, tend to be located far from population centers, and electricity transmission lines must bridge that gap. In addition to its importance for meeting renewable energy goals, a better connected and more robust transmission system also bolsters reliability because it can draw on many generation sources in the event that a generator or segment of the transmission network fails. And transmission facilitates generator competition by making it possible to transport lower-cost electricity from one part of the country to another area with higher electricity prices. Unfortunately, the current regulatory regime for siting transmission facilities has proven to be a barrier to needed transmission development. Historically, states have authority over physical siting of transmission lines whereas the federal government and Federal Energy Regulatory Commission (FERC) have had jurisdiction over the actual interstate transmission and sale of electricity. This division of power still exists today, despite recent legislative and regulatory attempts to overcome the limitations of the current federalism balance. With a focus on transmission challenges in Maine and New England, this Comment explores the current regulatory model and its balance of power between the federal and state governments and evaluates solutions proposed by commentators

The Filed-rate Doctrine: Leaving Regulation to the Regulators

NT Library Week, 14-19 May 1984. Opening party at Darwin Botanic Gardens. Julii Tyson (Conservation Commission Library) looking at votes in Best Book Poll.Suttor, T

Gallifrey Falls No More: Doctor Who’s Ontology of Time

Despite being time-travel adventure series, both classic Doctor Who (1963-1989, 1996) and its reboot (2005-present) have not seen the development of a coherent ontology of time for their fictional universe. As such, it is extremely difficult to review established theories of the nature of time in an attempt to shoe-horn Doctor Who into an existing framework. Difficulties include the evolution of the views of the central character, the alien “Doctor,” from a position that insists “time can’t be rewritten” to its opposite as well as a curious anthropomorphizing of the temporal through show concepts like “fixed points in time.” I argue that one way to draw a coherent philosophy of time from the program is to treat the Time Lords as establishing not only the possibility of time travel but also the universe’s timeline itself. This leads to an examination of four-dimensional realism as characterizing the ontology of Doctor Who’s fictive timeline

THE IMPACT OF POSTTRAUMATIC STRESS DISORDER ON PERIPHERAL VASCULAR FUNCTION

The physiological manifestations of posttraumatic stress disorder (PTSD) have been associated with an increase in risk of cardiovascular disease (CVD) independent of negative lifestyle factors. Peripheral vascular dysfunction may be a mechanism by which PTSD increases CVD risk via increases in oxidative stress, inflammation, and/or sympathetic nervous system activity. PURPOSE: This study sought to examine peripheral vascular function in those with PTSD compared to age-matched controls. METHODS: Eight individuals with PTSD (5 women, 3 men; age 22 ± 2 years), and sixteen healthy controls (CON; 10 women, 6 men, 23 ± 2 years), participated in the study. Leg vascular function was assessed via passive leg movement (PLM) technique and evaluated with Doppler ultrasonography. PLM-induced increases in leg blood flow were quantified as peak change in blood flow from baseline (ΔPeak LBF) and blood flow area under the curve (LBF AUC). RESULTS: Significant differences in leg vascular function were revealed between groups. The PTSD group reported significantly lower ΔPeak LBF (PTSD: 294.16 ± 54.16; CON: 594.78 ± 73.70 ml∙min-1; p = 0.01) and LBF AUC (PTSD: 57.23 ± 24.37; CON: 169.92 ± 29.84 ml; p = 0.02) when compared to the CON group. CONCLUSION: This study revealed that lower limb vascular function is impaired in individuals with PTSD when compared to healthy counterparts.https://scholarscompass.vcu.edu/gradposters/1043/thumbnail.jp

Weyl node with random vector potential

We study Weyl semimetals in the presence of generic disorder, consisting of a random vector potential as well as a random scalar potential. We derive renormalization group flow equations to second order in the disorder strength. These flow equations predict a disorder-induced phase transition between a pseudo-ballistic weak-disorder phase and a diffusive strong-disorder phase for sufficiently strong random scalar potential or for a pure three-component random vector potential. We verify these predictions using a numerical study of the density of states near the Weyl point and of quantum transport properties at the Weyl point. In contrast, for a pure single-component random vector potential the diffusive strong-disorder phase is absent.Comment: published version with minor change

Determining the Impact of Increased Physical Activity on Improving Sleep Quality in Young Adults

Determining the Impact of Increased Physical Activity on Improving Sleep Quality in Young Adults Disturbed sleep, defined as any alteration to normal sleep patterns, has been linked to poor cardiovascular health and an increase in cardiovascular disease (CVD) risk. These negative sleep patterns are highly prevalent with 35% to 41% of individuals in the United States reported some form of disturbed sleep. Although high amounts of physical activity (PA) are often associated with high sleep quality, little is known about PA’s effectiveness to improve different aspects of sleep (e.g. duration vs quality) and the mechanisms to which it can improve sleep quality. Purpose: The study sought to determine the ability of increased PA to improve sleep efficiency in healthy young adults. Methods: Nineteen young adults (25±4 yrs) were recruited for this study. Subjects wore an accelerometer (Actigraph GT3x-BT) for a total of three weeks to record daily physical activity (step count; low, moderate, and vigorous physical activity) and sleep variables (efficiency, wake after sleep onset, number of nightly awakenings, time per awakening, and total sleep time). Subjects maintained normal physical activity levels for the first week (BL), then increased their step count by an average of 5,000 steps/day across the next two weeks (W1 and W2). Heart rate variability (HRV) and venous blood draws were collected weekly to assess sympathetic activity and inflammation, respectively. Results: The physical activity intervention resulted in significant increases (p \u3c 0.001) in step-count for both W1 (13163 ± 3184) and W2 (12168 ± 3619) when compared to BL (8648 ± 2615 steps/day). No significant differences from BL were observed when examining sleep efficiency (BL: 83.8 ± 6.4; W1: 85.5 ± 4.0; W2: 84.2 ± 6.1 %), sympathetic-vagal balance, and inflammatory marker concentrations in W1 and W2. A significant correlation was revealed when assessing the change in sleep efficiency from BL to W1 (r = 0.81, p \u3c 0.001) and BL to W2 (r = 0.52, p = 0.02) when compared to initial sleep efficiency values. Conclusion: This study revealed that although young healthy individuals appear to lack improvements in sleep efficiency with an increase in physical activity, those who reported the lowest sleep quality had the greatest improvements in sleep efficiency following an increase in physical activity. Therefore, the findings of the study suggest that although increasing physical activity can improve sleep quality, a potential “ceiling effect” may occur, as when sleep quality is adequate, augmenting physical activity no longer has a substantial effect.https://scholarscompass.vcu.edu/gradposters/1058/thumbnail.jp

Hyperspectral Point Cloud Projection for the Semantic Segmentation of Multimodal Hyperspectral and Lidar Data with Point Convolution-Based Deep Fusion Neural Networks

The fusion of dissimilar data modalities in neural networks presents a significant challenge, particularly in the case of multimodal hyperspectral and lidar data. Hyperspectral data, typically represented as images with potentially hundreds of bands, provide a wealth of spectral information, while lidar data, commonly represented as point clouds with millions of unordered points in 3D space, offer structural information. The complementary nature of these data types presents a unique challenge due to their fundamentally different representations requiring distinct processing methods. In this work, we introduce an alternative hyperspectral data representation in the form of a hyperspectral point cloud (HSPC), which enables ingestion and exploitation with point cloud processing neural network methods. Additionally, we present a composite fusion-style, point convolution-based neural network architecture for the semantic segmentation of HSPC and lidar point cloud data. We investigate the effects of the proposed HSPC representation for both unimodal and multimodal networks ingesting a variety of hyperspectral and lidar data representations. Finally, we compare the performance of these networks against each other and previous approaches. This study paves the way for innovative approaches to multimodal remote sensing data fusion, unlocking new possibilities for enhanced data analysis and interpretation