263 research outputs found

    Service-led Catch-Up in the Indian Economy: Alternative Hypotheses on Tertiarization and the Leapfrogging Thesis

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    The experience of India in economic catch-up is unique when compared to other countries. First, the catch-up process of India was not only service-led, but also accompanied by a decoupling between manufacturing and services. Second, productivity performance in the service sector was higher than in the manufacturing sector in terms of the level as well as growth rate. Finally, exports in IT services led the tertiarization of the Indian economy. From this perspective, the trajectory of the Indian catch-up can be characterized as path-creating. Existing hypotheses on tertiarization do not fully account for such aspects of the uniqueness of the Indian experience. The leapfrogging argument in Neo-Schumpeterian economics provides a more plausible explanation of the Indian experience. The ICT revolution and the shift from hardware systems to client-server systems have created new markets for the global services trade. This paradigm shift lowered the costs of entry, including fixed investments, for Indian IT service firms and helped close the experience and skill gaps quickly. The industry-specific characteristics of the IT services industry and the country-specific advantages of India further lowered the costs of entry. With steady strategic and organizational innovations, Indian IT service firms succeeded in securing competitive advantages in the global market

    Acute Effect of Active Tibial Rotation Exercise on Tibial Torsion Angle, Ankle Range of Motion, and Neuromuscular Control

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    PURPOSE This study aimed to analyze the acute effect of active tibial rotation exercise on tibial torsion angle, ankle range of motion, and neuromuscular control. METHODS This study was based on AB/BA Cross-over design, and participants were divided into two conditions (core-tex tibial and manual tibial rotation exercises). Before and after the exercise intervention, tibial torsion angle, non-weight bearing ankle range of motion, weight-bearing ankle range of motion and dynamic balance test, and Shark skill test were conducted. RESULTS An interaction effect was found in the left non-weight-bearing ankle range of motion and the right posterolateral (PL) of the Y Balance Test. In addition, there were significant differences between periods in left tibial torsion angle, non-weight-bearing ankle range of motion, bilateral weight-bearing ankle range of motion, bilateral AN, bilateral posteromedial, right PL, bilateral composite score, and bilateral Shark skill test. CONCLUSIONS Tibial rotation exercise is considered valuable as sports injury prevention training due to its effectiveness for lower extremities functionally and structurally regardless of tibial rotation exercise type

    Effects of the Non-Face-To-Face Learning on Health-Related Physical Fitness and Balance in Adolescents According to COVID-19

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    Abstracts PURPOSE This study aimed to examine the effects of non-face-to-face learning on health-related physical fitness and balance in adolescents according to the coronavirus disease 2019 (COVID-19). METHODS Twenty-nine middle-school students (14 girls and 15 boys) were enrolled. We measured the students' health-related physical fitness (body composition, muscle strength, muscle endurance, flexibility, and cardiac endurance) and balance (static and dynamic) before and after 12 weeks of non-face-to-face learning without any exercise intervention. Cardiac endurance was measured using the Harvard step test. RESULTS Body fat, muscle strength (hip flexion, hip extension, knee flexion, knee extension), and Y-balance test exhibited significant differences before and after non-face-to-face learning (p<.05). Body fat, muscle strength (hip flexion, hip extension), and Y-Balance test exhibited significant differences in the female group (p<.05). Hip extension muscle strength exhibited a significant difference in the male group (p<.05). Analysis of covariance showed that muscle strength (hip extension and knee extension) and Harvard step of the female group were significantly decreased compared to the male group (p<.05). CONCLUSIONS Non-face-to-face classes according to COVID-19 had a negative effect on health-related physical fitness and balance in adolescents. Particularly, the muscle strength and cardiac endurance of female adolescents were lower than those of male adolescents

    Substance P and beta-endorphin mediate electro-acupuncture induced analgesia in mouse cancer pain model

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    <p>Abstract</p> <p>Background</p> <p>Opioid analgesics are generally used to combat the pain associated with cancerous conditions. These agents not only inhibit respiratory function and cause constipation, but also induce other significant side effects such as addiction and tolerance, all of which further contribute to a reduced quality of life for cancer patients. Thus, in the present study, the effects of electro-acupuncture treatment (EA) on mechanical allodynia were examined in a cancer pain mouse model.</p> <p>Methods</p> <p>In order to produce a neuropathic cancer pain model, S-180 sarcoma cells were inoculated around the sciatic nerve of left legs of Balb/c mice. Magnetic Resonance Imaging (MRI) scanning confirmed the mass of S-180 cancer cells embedded around the sciatic nerve. Mechanical allodynia was most consistently induced in the mouse sarcoma cell line S-180 (2 × 10<sup>6</sup>sarcoma cells)-treated group compared to all the other groups studied. EA stimulation (2 Hz) was administered daily to ST36 (Zusanli) of S-180 bearing mice for 30 min for 9 days after S-180 inoculation.</p> <p>Results</p> <p>EA treatment significantly prolonged paw withdrawal latency from 5 days after inoculation. It also shortened the cumulative lifting duration from 7 days after inoculation, compared to the tumor control. Also, the overexpression of pain peptide substance P in the dorsal horn of the spinal cord was significantly decreased in the EA-treated group compared to the tumor control on Day 9 post inoculation. Furthermore, EA treatment effectively increased the concentration of β-endorphin in blood and brain samples of the mice to a greater extent than that of the tumor control as well as the normal group. The concentration of β-endorphin for EA treatment group increased by 51.457% in the blood and 12.6% in the brain respectively, compared to the tumor control group.</p> <p>Conclusion</p> <p>The findings of this study suggest that a S-180 cancer pain model is useful as a consistent and short time animal model. It also indicated that EA treatment could be used as an alternative therapeutic method for cancer pain due to a consequent decrease in substance P and increase in β-endorphin levels.</p

    Application of AutoFom III equipment for prediction of primal and commercial cut weight of Korean pig carcasses

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    Objective This study was conducted to enable on-line prediction of primal and commercial cut weights in Korean slaughter pigs by AutoFom III, which non-invasively scans pig carcasses early after slaughter using ultrasonic sensors. Methods A total of 162 Landrace, Yorkshire, and Duroc (LYD) pigs and 154 LYD pigs representing the yearly Korean slaughter distribution were included in the calibration and validation dataset, respectively. Partial least squares (PLS) models were developed for prediction of the weight of deboned shoulder blade, shoulder picnic, belly, loin, and ham. In addition, AutoFom III’s ability to predict the weight of the commercial cuts of spare rib, jowl, false lean, back rib, diaphragm, and tenderloin was investigated. Each cut was manually prepared by local butchers and then recorded. Results The cross-validated prediction accuracy (R2cv) of the calibration models for deboned shoulder blade, shoulder picnic, loin, belly, and ham ranged from 0.77 to 0.86. The R2cv for tenderloin, spare rib, diaphragm, false lean, jowl, and back rib ranged from 0.34 to 0.62. Because the R2cv of the latter commercial cuts were less than 0.65, AutoFom III was less accurate for the prediction of those cuts. The root mean squares error of cross validation calibration (RMSECV) model was comparable to the root mean squares error of prediction (RMSEP), although the RMSECV was numerically higher than RMSEP for the deboned shoulder blade and belly. Conclusion AutoFom III predicts the weight of deboned shoulder blade, shoulder picnic, loin, belly, and ham with high accuracy, and is a suitable process analytical tool for sorting pork primals in Korea. However, AutoFom III’s prediction of smaller commercial Korean cuts is less accurate, which may be attributed to the lack of anatomical reference points and the lack of a good correlation between the scanned area of the carcass and those traits

    Study on the obesity and nutrition status of housewives in Seoul and Kyunggi area

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    This study was conducted to evaluate the rate of obesity of 212 women (age 45-60 years) in Seoul and the Kyunggi area through analysis of BMI and the dietary life factors related to obesity using a survey on dietary habits, dietary assessment, and nutrient intake. The height of the underweight group was taller than normal. The height of the obese group was equal to that of the normal group, but the weight was 8.5 kg greater than the normal group. Women in the underweight group consumed meals irregularly, and only 33.4% ate breakfast. Additionally, the rate of overeating was low in the underweight group, and milk, dairy products (yogurt, etc.), fruit, and fruit juice were consumed more than once a day. It was found that 62.1% of the women in the obese group never ate out, and the rate of eating one serving of fruit, drinking one cup of fruit juice, and eating various kinds of foods was high. The average point of women's dietary life was 21.9 ± 2.9, and 12.7% of all women responded that their dietary life was good. However, in the obese group, only 6.9% of the women reported that their dietary life was good. Evaluation of snacking habits revealed that the underweight group consumed a high level of carbonated drinks and ice cream, whereas for in the obese group, 24.1% of the women consumed milk and its products and 5.6% regularly consumed fast and fried foods. Evaluation of nutrient intake revealed that the consumption of energy, protein, vitamin A, vitamin B1, B2, B6, niacin, vitamin C, and vitamin E was high in all of the groups, but the intake of folic acid in the underweight group was lower than the required level. Overall, 24.1% of the women in the obese group were found to have metabolic diseases, mostly hypertension (43%). In conclusion, a balanced diet to avoid excessive nutrient intake is needed to prevent obesity

    Acute respiratory alkalosis occurring after endoscopic third ventriculostomy -A case report-

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    An endoscopic third ventriculostomy was performed in a 55-year-old man with an obstructive hydrocephalus due to aqueductal stenosis. The vital signs and laboratory studies upon admission were within the normal limits. Anesthesia was maintained with nitrous oxide in oxygen and 6% desflurane. The patient received irrigation with approximately 3,000 ml normal saline during the procedure. Anesthesia and operation were uneventful. However, he developed postoperative hyperventilation in the recovery room, and arterial blood gas analysis revealed acute respiratory alkalosis. We report a rare respiratory alkalosis that occurred after an endoscopic third ventriculostomy

    Imaging of Viral Thymidine Kinase Gene Expression by Replicating Oncolytic Adenovirus and Prediction of Therapeutic Efficacy

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    PURPOSE: We have used a genetically attenuated adenoviral vector which expresses HSVtk to assess the possible additive role of suicidal gene therapy for enhanced oncolytic effect of the virus. Expression of TK was measured using a radiotracer-based molecular counting and imaging system. MATERIALS AND METHODS: Replication-competent recombinant adenoviral vector (Ad-DeltaE1B19/55) was used in this study, whereas replication-incompetent adenovirus (Ad-DeltaE1A) was generated as a control. Both Ad-DeltaE1B19/55-TK and Ad-DeltaE1A-TK comprise the HSVtk gene inserted into the E3 region of the viruses. YCC-2 cells were infected with the viruses and incubated with 2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl-5-iodouracil (I-131 FIAU) to measure amount of radioactivity. The cytotoxicity of the viruses was determined, and gamma ray imaging of HSVtk gene was performed. MTT assay was also performed after GCV treatment. RESULTS: On gamma counter-analyses, counts/ minute (cpm)/microg of protein showed MOIs dependency with DeltaE1B19/55-TK infection. On MTT assay, Ad-DeltaE1B19/55-TK led to more efficient cell killing than Ad-DeltaE1A-TK. On plate imaging by gamma camera, both Ad-DeltaE1B19/55-TK and Ad-DeltaE1A-TK infected cells showed increased I-131 FIAU uptake in a MOI dependent pattern, and with GCV treatment, cell viability of DeltaE1B19/55-TK infection was remarkably reduced compared to that of Ad-DeltaE1A-TK infection. CONCLUSION: Replicating Ad-DeltaE1B19/55-TK showed more efficient TK expression even in the presence of higher-cancer cell killing effects compared to non-replicating Ad-DeltaE1A-TK. Therefore, GCV treatment still possessed an additive role to oncolytic effect of Ad-DeltaE1B19/55-TK. The expression of TK by oncolytic viruses could rapidly be screened using a radiotracer-based counting and imaging technique.ope
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