Qualitative Effects of Knowledge Rules in Probabilistic Data Integration

One of the problems in data integration is data overlap: the fact that different data sources have data on the same real world entities. Much development time in data integration projects is devoted to entity resolution. Often advanced similarity measurement techniques are used to remove semantic duplicates from the integration result or solve other semantic conflicts, but it proofs impossible to get rid of all semantic problems in data integration. An often-used rule of thumb states that about 90% of the development effort is devoted to solving the remaining 10% hard cases. In an attempt to significantly decrease human effort at data integration time, we have proposed an approach that stores any remaining semantic uncertainty and conflicts in a probabilistic database enabling it to already be meaningfully used. The main development effort in our approach is devoted to defining and tuning knowledge rules and thresholds. Rules and thresholds directly impact the size and quality of the integration result. We measure integration quality indirectly by measuring the quality of answers to queries on the integrated data set in an information retrieval-like way. The main contribution of this report is an experimental investigation of the effects and sensitivity of rule definition and threshold tuning on the integration quality. This proves that our approach indeed reduces development effort — and not merely shifts the effort to rule definition and threshold tuning — by showing that setting rough safe thresholds and defining only a few rules suffices to produce a ‘good enough’ integration that can be meaningfully used

Quality Measures in Uncertain Data Management

Many applications deal with data that is uncertain. Some examples are applications dealing with sensor information, data integration applications and healthcare applications. Instead of these applications having to deal with the uncertainty, it should be the responsibility of the DBMS to manage all data including uncertain data. Several projects do research on this topic. In this paper, we introduce four measures to be used to assess and compare important characteristics of data and systems

User Feedback in Probabilistic XML

Data integration is a challenging problem in many application areas. Approaches mostly attempt to resolve semantic uncertainty and conflicts between information sources as part of the data integration process. In some application areas, this is impractical or even prohibitive, for example, in an ambient environment where devices on an ad hoc basis have to exchange information autonomously. We have proposed a probabilistic XML approach that allows data integration without user involvement by storing semantic uncertainty and conflicts in the integrated XML data. As a\ud consequence, the integrated information source represents\ud all possible appearances of objects in the real world, the\ud so-called possible worlds.\ud \ud In this paper, we show how user feedback on query results\ud can resolve semantic uncertainty and conflicts in the\ud integrated data. Hence, user involvement is effectively postponed to query time, when a user is already interacting actively with the system. The technique relates positive and\ud negative statements on query answers to the possible worlds\ud of the information source thereby either reinforcing, penalizing, or eliminating possible worlds. We show that after repeated user feedback, an integrated information source better resembles the real world and may converge towards a non-probabilistic information source

TSE pathogenesis in cattle and sheep

Many studies have been undertaken in rodents to study the pathogenesis of transmissible spongiform encephalopathies (TSE). Only a few studies have focused on the pathogenesis of bovine spongiform encephalopathy (BSE) and scrapie in their natural hosts. In this review, we summarize the most recent insights into the pathogenesis of BSE and scrapie starting from the initial uptake of TSE agents and crossing of the gut epithelium. Following replication in the gut-associated lymphoid tissues (GALT), TSE agents spread to the enteric nervous system (ENS) of the gut. Infection is then carried through the efferent fibers of the post-ganglionic neurons of the parasympathetic and sympathetic nervous system to the pre-ganglionic neurons in the medulla oblongata of the brain and the thoracic segments of the spinal cord. The differences between the pathogenesis of BSE in cattle and scrapie in sheep are discussed as well as the possible existence of additional pathogenetic routes

06472 Abstracts Collection - XQuery Implementation Paradigms

From 19.11.2006 to 22.11.2006, the Dagstuhl Seminar 06472 ``XQuery Implementation Paradigms'' was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl. During the seminar, several participants presented their current research, and ongoing work and open problems were discussed. Abstracts of the presentations given during the seminar as well as abstracts of seminar results and ideas are put together in this paper. The first section describes the seminar topics and goals in general. Links to extended abstracts or full papers are provided, if available

Differentiation of ruminant transmissible spongiform encephalopathy isolate types, including bovine spongiform encephalopathy and CH1641 scrapie

With increased awareness of the diversity of transmissible spongiform encephalopathy (TSE) strains in the ruminant population, comes an appreciation of the need for improved methods of differential diagnosis. Exposure to bovine spongiform encephalopathy (BSE) has been associated with the human TSE, variant Creutzfeldt–Jakob disease, emphasizing the necessity in distinguishing low-risk TSE types from BSE. TSE type discrimination in ruminants such as cattle, sheep, goats and deer, requires the application of several prion protein (PrP)-specific antibodies in parallel immunochemical tests on brain homogenates or tissue sections from infected animals. This study uses in a single incubation step, three PrP-specific antibodies and fluorescent Alexa dye-labelled anti-mouse Fabs on a Western blot. The usual amount of brain tissue needed is 0.5 mg. This multiplex application of antibodies directed towards three different PrP epitopes enabled differential diagnosis of all established main features of classical scrapie, BSE and Nor98-like scrapie in sheep and goats, as well as the currently known BSE types C, H and L in cattle. Moreover, due to an antibody-dependent dual PrP-banding pattern, for the first time CH1641 scrapie of sheep can be reliably discriminated from the other TSE isolate types in sheep

Regrowth potential of shoot and of roots of Rhodes grass (Chloris gayana Kunth) after defoliation.

In field and pot trials the effect of different lengths of pre-cutting periods and of cutting intervals on regrowth of shoot and of root were studied in Rhodes grass cv. Katambora. The initial regrowth of the sward after a long (28 days) pre-cutting period was slower than after a short (7 days) pre-cutting period. The reduction of the residual LAI following the extension of the pre-cutting period was associated with reduction in the number of tillers capable of regrowth after defoliation. Root wt. decreased drastically following cutting when the initial root wt. was high (long pre-cutting period), but little when the initial root wt. was small (short pre-cutting period). The decrease in root wt. lasted c. 1 wk after which it increased at a more or less constant rate proportional to the increase of shoot wt. irrespective of the length of the pre-cutting period. The lack of the capability of tillers to regrow after cutting was closely related with developmental stage of tillers. Since tillers of subtropical and tropical grasses have a tendency for early stem elongation, it was concluded that the relatively small number of sites available for regrowth in these grasses is the major deterrent for quick shoot growth of the sward after defoliation. (Abstract retrieved from CAB Abstracts by CABI’s permission