12,392 research outputs found
Taylor dispersion of gyrotactic swimming micro-organisms in a linear flow
The theory of generalized Taylor dispersion for suspensions of Brownian particles is developed to study the dispersion of gyrotactic swimming micro-organisms in a linear shear flow. Such creatures are bottom-heavy and experience a gravitational torque which acts to right them when they are tipped away from the vertical. They also suffer a net viscous torque in the presence of a local vorticity field. The orientation of the cells is intrinsically random but the balance of the two torques results in a bias toward a preferred swimming direction. The micro-organisms are sufficiently large that Brownian motion is negligible but their random swimming across streamlines results in a mean velocity together with diffusion. As an example, we consider the case of vertical shear flow and calculate the diffusion coefficients for a suspension of the alga <i>Chlamydomonas nivalis</i>. This rational derivation is compared with earlier approximations for the diffusivity
Effects of high-energy ionizing particles on the Si:As mid-infrared detector array on board the AKARI satellite
We evaluate the effects of high-energy ionizing particles on the Si:As
impurity band conduction (IBC) mid-infrared detector on board AKARI, the
Japanese infrared astronomical satellite. IBC-type detectors are known to be
little influenced by ionizing radiation. However we find that the detector is
significantly affected by in-orbit ionizing radiation even after spikes induced
by ionizing particles are removed. The effects are described as changes mostly
in the offset of detector output, but not in the gain. We conclude that the
changes in the offset are caused mainly by increase in dark current. We
establish a method to correct these ionizing radiation effects. The method is
essential to improve the quality and to increase the sky coverage of the AKARI
mid-infrared all-sky-survey map.Comment: 16 pages, 8 figures, 1 table, accepted for publication in PAS
Analytic approach to the evolutionary effects of genetic exchange
We present an approximate analytic study of our previously introduced model
of evolution including the effects of genetic exchange. This model is motivated
by the process of bacterial transformation. We solve for the velocity, the rate
of increase of fitness, as a function of the fixed population size, . We
find the velocity increases with , eventually saturated at an which
depends on the strength of the recombination process. The analytical treatment
is seen to agree well with direct numerical simulations of our model equations
Stable expansion of high-grade serous ovarian cancer organoids requires a low-Wnt environment
Interpretative modelling of a geological cross section from boreholes: sources of uncertainty and their quantification
We conducted a designed experiment to quantify sources of uncertainty in geologists' interpretations of a geological cross section. A group of 28 geologists participated in the experiment. Each interpreted borehole record included up to three Palaeogene bedrock units, including the target unit for the experiment: the London Clay. The set of boreholes was divided into batches from which validation boreholes had been withheld; as a result, we obtained 129 point comparisons between the interpreted elevation of the base of the London Clay and its observed elevation in a borehole not used for that particular interpretation. Analysis of the results showed good general agreement between the observed and interpreted elevations, with no evidence of systematic bias. Between-site variation of the interpretation error was spatially correlated, and the variance appeared to be stationary. The between-geologist component of variance was smaller overall, and depended on the distance to the nearest borehole. There was also evidence that the between-geologist variance depends on the degree of experience of the individual. We used the statistical model of interpretation error to compute confidence intervals for any one interpretation of the base of the London Clay on the cross section, and to provide uncertainty measures for decision support in a hypothetical route-planning process. The statistical model could also be used to quantify error propagation in a full 3-D geological model produced from interpreted cross sections
Measurement of electron screening in muonic lead
Energies of the transitions between high-lying (n≥6) states of muonic lead were accurately determined. The results are interpreted as a ∼2% test of the electron screening. The agreement between experiment and theory is good if it is assumed that the refilling of the electron K shell is fast. The present results furthermore severely restrict possible ionization of the electron L shell
Stretching Instability of Helical Spring
We show that when a gradually increasing tensile force is applied to the ends
of a helical spring with sufficiently large ratios of radius to pitch and twist
to bending rigidity, the end-to-end distance undergoes a sequence of
discontinuous stretching transitions. Subsequent decrease of the force leads to
step-like contraction and hysteresis is observed. For finite helices, the
number of these transitions increases with the number of helical turns but only
one stretching and one contraction instability survive in the limit of an
infinite helix. We calculate the critical line that separates the region of
parameters in which the deformation is continuous from that in which stretching
instabilities occur, and propose experimental tests of our predictions.Comment: 5 pages, 4 figure
Phase-Field Model of Mode III Dynamic Fracture
We introduce a phenomenological continuum model for mode III dynamic fracture
that is based on the phase-field methodology used extensively to model
interfacial pattern formation. We couple a scalar field, which distinguishes
between ``broken'' and ``unbroken'' states of the system, to the displacement
field in a way that consistently includes both macroscopic elasticity and a
simple rotationally invariant short scale description of breaking. We report
two-dimensional simulations that yield steady-state crack motion in a strip
geometry above the Griffith threshold.Comment: submitted to PR
Analytical study of the effect of recombination on evolution via DNA shuffling
We investigate a multi-locus evolutionary model which is based on the DNA
shuffling protocol widely applied in \textit{in vitro} directed evolution. This
model incorporates selection, recombination and point mutations. The simplicity
of the model allows us to obtain a full analytical treatment of both its
dynamical and equilibrium properties, for the case of an infinite population.
We also briefly discuss finite population size corrections
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