MESH USAGE IN PELVIC ORGAN PROLAPSE SURGERY

Pelvic organ prolapse is descent of pelvic organs from their normal position. Several abdominal and vaginal operations have been designed for the treatment of pelvic organ prolapse. Native tissue or meshes can be used during these operations. Studies suggesting increased recurrence rate after plication with native tissue, have popularized the use of vaginal mesh surgery. Biologic and synthetic materials and mesh kits have been designed for this purpose. However, there is still debate about the indications of these procedures, short and long-term complications, and success rates

EVALUATION OF THE EFFECTS OF HYSTERECTOMY ON OVARIAN RESERVE BY ANTIMULLERIAN HORMONE AND ULTRASONOGRAPHY

Objective: Our study aimed to determine the risk of premature ovarian failure of patients to whom hysterectomy was performed without oophorectomy

Sonographic depiction of fetal ureters

Aims: Classic literature states that the fetal ureter should not be visible unless dilated. Our main objective was to produce an effective, reproducible method for fetal ureter depiction during an anatomic survey. Our secondary objectives were to record the frequency of visible ureters among normal fetuses and among fetuses with mild pyelectasis and also to determine the diameter of the sonographically demonstrated ureter

Effect of elevated progesterone level in antagonist cycles on the day of hCG on cleavage day and blastocyst transfer

Objective: To evaluate the association between progesterone elevation on the day of human chorionic gonadotropin (hCG) administration and clinical pregnancy rates of gonadotropin-releasing hormone (GnRH) antagonist in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles with the transfer of embryos at different developmental stages (day-3 versus day-5 ETs)

Blastocyst transfer does not improve cycle outcome as compared to D3 transfer in antagonist cycles with an elevated progesterone level on the day of hCG

Objective: To evaluate the association between progesterone elevation on the day of human chorionic gonadotropin (hCG) administration and clinical pregnancy rates of gonadotropin-releasing hormone (GnRH) antagonist in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles with the transfer of embryos at different developmental stages (day-3 versus day-5 ETs)

The role of ovarian reserve markers in prediction of clinical pregnancy

To evaluate the role of ovarian reserve markers in the prediction of clinical pregnancy and embryo transfer accomplishment among poor responder IVF applicants. 304 female poor responder IVF applicants were included in this prospective cohort study conducted at the IVF-unit. Antral follicle count, FSH, LH, E2, AMH and IVF outcomes were compared in pregnant and non-pregnant groups as well as in ET vs. non-ET groups. The number of retrieved oocytes was significantly correlated positively with AMH and AFC, and negatively with FSH and age. Quartiles of FSH and AFC were similar to the rate of pregnancy. Quartiles of AMH (75%) were statistically significant. Mean serum levels for AMH were significantly lower in the non-ET group. Our findings seem to indicate that day 3 AMH values can predict ET accomplishment with a sensitivity of 96% and a specificity of 35%. Quartiles of AMH <25% (<0.21ng/mL) can predict the IVF results among poor responder IVF applicants.Impact statementVarious cut-off values have been determined for day 3 serum AMH values. These values help to determine the groups that are expected to give normal, high or low response to stimulation and decide the treatment options.In contrast to other groups of patients, poor responders cannot reach the embryo transfer stage for several reasons. These are; absence of a mature oocyte after oocyte pick-up, fertilisation failure without male factor or poor embryo quality.In the present study; a cut-off value of 0.33ng/mL for the prediction of ET accomplishment in poor responder patients was determined with a sensitivity of 96%. Additionally, clinical pregnancy could not be achieved under the value of 0.21ng/mL day 3 AMH values.It is important to clarify the embryo transfer success of poor responder patients prior to expected treatment success. Pre-treatment counselling for these patients would lessen the disappointment that may develop after treatment. The cost-effectiveness of treatments below these AMH values can be determined by further studies

Cognitive deficits in clinical and familial high risk groups for psychosis are common as in first episode schizophrenia

The aim of this sudy is to compare the neurocognitive functions in individuals with clinical or genetic risk for psychosis, in patients with first-episode schizophrenia (FES) and in healthy controls

Cognitive deficits in clinical and familial high risk groups for psychosis are common as in first episode schizophrenia

The aim of this sudy is to compare the neurocognitive functions in individuals with clinical or genetic risk for psychosis, in patients with first-episode schizophrenia (FES) and in healthy controls

Distinguishing the progression of an endometrioma: Benign or malignant?

Objective: To elucidate the immunohistochemical (IHC) differences of endometrioma tissues that may have the potential to progress to ovarian clear cell carcinoma (OCCC) by using KRAS, HNF1 beta, PIK3CA, PPP2R1A, and ARID1A as biomarkers