68 research outputs found
The potential differences between multiple central terminals each connected to a separate set of limb electrodes
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32550/1/0000666.pd
Observations on the potential variations of the cavities of the right side of the human heart
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32554/1/0000671.pd
Assessment of Synaptic Function During Short-Term Facilitation in Motor Nerve Terminals in the Crayfish
An enhanced buildup of [Ca2+]i occurs during short-term facilitation (STF) at the crayfish neuromuscular junction (NMJ). As a model system, this NMJ allows discrete postsynaptic quantal events to be counted and characterized in relation to STF. Providing 10 pulses, at 20 and 40Hz, we monitored postsynaptic quantal events over a discrete region of a nerve terminal with a focal macropatch electrode. Characteristics of quantal events were clustered into groups by peak amplitude and time to the peak amplitude. Since the synapses at this NMJ have varied spacing of active zones, number of active zones and synaptic size, the graded nature of synaptic recruitment is likely one means of titrating synaptic efficacy for the graded depolarization on the non-spiking muscle fiber. Synapses in this preparation would appear to have a quantal signature that can be used for quantifying their activity which is useful in estimating the overall number of active sites. We use mixture modeling to estimate n (number of active sites) and p (probability of vesicle fusion) from the quantal characteristics. In a preparation that was stimulated at 40Hz, synapses were recruited (increase in n) and the number active synapses increased in p. In a different preparation, p increased as the stimulation was changed from 20 to 40Hz, but n did not show a substantial increase; however, during the STF train, p increases slightly. This study provides a novel approach in determining subsets of the single evoked quanta to better estimate n and p which describe synaptic function
Update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol: statistical analysis plan for a prospective, multicenter, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial.
BACKGROUND: Observational research suggests that combined therapy with Vitamin C, thiamine and hydrocortisone may reduce mortality in patients with septic shock.
METHODS AND DESIGN: The Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) trial is a multicenter, double-blind, adaptive sample size, randomized, placebo-controlled trial designed to test the efficacy of combination therapy with vitamin C (1.5βg), thiamine (100βmg), and hydrocortisone (50βmg) given every 6βh for up to 16 doses in patients with respiratory or circulatory dysfunction (or both) resulting from sepsis. The primary outcome is ventilator- and vasopressor-free days with mortality as the key secondary outcome. Recruitment began in August 2018 and is ongoing; 501 participants have been enrolled to date, with a planned maximum sample size of 2000. The Data and Safety Monitoring Board reviewed interim results at N =β200, 300, 400 and 500, and has recommended continuing recruitment. The next interim analysis will occur when N =β1000. This update presents the statistical analysis plan. Specifically, we provide definitions for key treatment and outcome variables, and for intent-to-treat, per-protocol, and safety analysis datasets. We describe the planned descriptive analyses, the main analysis of the primary end point, our approach to secondary and exploratory analyses, and handling of missing data. Our goal is to provide enough detail that our approach could be replicated by an independent study group, thereby enhancing the transparency of the study.
TRIAL REGISTRATION: ClinicalTrials.gov, NCT03509350. Registered on 26 April 2018
Synthesis of 7Ξ²-hydroxy-8-ketone opioid derivatives with antagonist activity at mu- and delta-opioid receptors
Despite extensive years of research, the direct oxidation of the 7,8-double bond of opioids has so far received little attention and knowledge about the effects of this modification on activity at the different opioid receptors is scarce. We herein report that potassium permanganate supported on iron(II) sulfate heptahydrate can be used as a convenient oxidant in the one-step, heterogeneous conversion of Delta(7.8)-opioids to the corresponding 7 beta-hydroxy-8-ketones. Details of the reaction mechanism are given and the effects of the substituent at position 6 of several opioids on the reaction outcome is discussed. The opioid hydroxy ketones prepared are antagonists at the mu- and delta-opioid receptors. Docking simulations and detailed structure-activity analysis revealed that the presence of the 7 beta-hydroxy-8-ketone functionality in the prepared compounds can be used to gain activity towards the delta opioid receptor. The 7 beta-hydroxy-8-ketones prepared with this method can also be regarded as versatile intermediates for the synthesis of other opioids of interest. (C) 2018 Elsevier Masson SAS. All rights reserved.Peer reviewe
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PiΓ±on-Juniper Reduction Increases Soil Water Availability of the Resource Growth Pool
Managers reduce piΓ±on (Pinus spp.) and juniper (Juniperus spp.) trees that are encroaching on sagebrush (Artemisia spp.)
communities to lower fuel loads and increase cover of desirable understory species. All plant species in these communities
depend on soil water held at >-1.5 MPa matric potential in the upper 0.3 m of soil for nutrient diffusion to roots and major
growth in spring (resource growth pool). We measured soil water matric potentials and temperatures using gypsum blocks and
thermocouples buried at 0.01β0.3 m on tree, shrub, and interspace microsites to characterize the seasonal soil climate of 13 tree-encroached sites across the Great Basin. We also tested the effects of initial tree infilling phase and tree control treatments of
prescribed fire, tree cutting, and tree shredding on time of available water and soil temperature of the resource growth pool on
nine sites. Both prescribed fire and mechanical tree reduction similarly increased the time that soil water was available (matric
potential >-1.5 MPa) in spring, but this increase was greatest (up to 26 d) when treatments were applied at high tree
dominance. As plant cover increased with time since treatment, the additional time of available water decreased. However, even
in the fourth year after treatment, available water was 8.6 d and 18 d longer on treatments applied at mid and high tree
dominance compared to untreated plots, indicating ongoing water availability to support continued increases in residual plants
or annual invaders in the future. To increase resistance to invasive annual grasses managers should either treat at lower or mid
tree dominance when there is still high cover of desirable residual vegetation or seed desirable species to use increased resources
from tree reduction. This strategy is especially critical on warmer sites, which have high climate suitability to invasive species
such as cheatgrass (Bromus tectorum L.)Keywords: infilling, resistance, resilience, soil temperature, mechanical treatments, prescribed fire, weed invasio
The contribution of the European Society for Soil Conservation (ESSC) to scientific knowledge, education and sustainability
Soil is an integral component of the global environmental system that supports the quality and diversity of
terrestrial life on Earth. Therefore, it is vital to consider the processes and impacts of soil degradation on society,
especially on the provision of environmental goods and services, including food security and climate change
mitigation and adaptation. Scientific societies devoted to Soil Science play significant roles in promoting soil
security by advancing scientific knowledge, education and environmental sustainability.
The European Society for Soil Conservation (ESSC) was founded in Ghent (Belgium) on 4 November
1988 by a group of 23 researchers from several European countries. It is an interdisciplinary, non-political
association with over 500 members in 56 countries. The ESSC produces and distributes a hardcopy Newsletter
twice a year and maintains both a website and Facebook page:
http://www.soilconservation.eu/
https://www.facebook.com/European-Society-for-Soil-Conservation-ESSC-100528363448094/
The ESSC aims to:
\u2022 Support research on soil degradation, soil protection and soil and water conservation.
\u2022 Provide a network for the exchange of knowledge about soil degradation processes and soil conservation research
and practises.
\u2022 Produce publications on major issues relating to soil degradation and soil and water conservation.
\u2022 Advise regulators and policy-makers on soil issues, especially soil degradation, protection and conservation.
The ESSC held its First International Congress in Silsoe (UK) in 1992. Further International Congresses
were held in Munich (1996), Valencia (2000), Budapest (2004), Palermo (2007), Thessaloniki (2011)
and Moscow (2015). The Eighth International Congress will be held in Lleida (Spain) in June 2017:
http://www.consowalleida2017.com/
Interspersed between these international congresses, the ESSC organizes annual international conferences
on specific topics. These include Imola, Italy (Biogeochemical Processes at Air-Soil-Water Interfaces and
Environmental Protection) in 2015 and Cluj-Napoca, Romania (Soil: Our Common Future) in 2016. Since its
inception, the Society has made significant advances, including developing a strong and growing global network
of soil scholars.
The ESSC honours major individual contributions to soil conservation through two awards made every
four years at its Congresses, namely:
\u2022 The \u2018Gerold Richter Award,\u2019 awarded to a person who has, over their career, made significant and internationally
recognized contributions to the investigation and/or promotion of soil conservation in Europe.
\u2022 The \u2018Young Person\u2019s Award\u2019 is presented to a member of the Society, aged 40 years or less, who over
the previous four years has made important contributions to soil conservation in Europe through research, practise,
policy-making or another relevant activity.
The ESSC provides grants to young members to attend its conferences and promotes the organization of
scientific meetings, soil conservation research, and co-operation between numerous institutions and individuals
on soil conservation initiatives. The societal challenges that can be addressed through better soil protection, as
well as developing new knowledge and scientific approaches to soil protection and sustainable management, mean
the ESSC embraces the on-going development, application, review and criticism of highly innovative scientific
methods for soil conservation. It is in this context that the ESSC analyses and publicizes the roles and functions
of soil in natural and human-modified systems and the functional optimization of soils to ensure sustainable
environmental protection
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Understory Cover Responses to PiΓ±on-Juniper Treatments Across Tree Dominance Gradients in the Great Basin
PiΓ±on (Pinus spp.) and juniper (Juniperus spp.) trees are reduced to restore native vegetation and avoid severe fires where they have expanded into sagebrush (Artemisia tridentata Nutt.) communities. However, what phase of tree infilling should treatments target to retain desirable understory cover and avoid weed dominance? Prescribed fire and tree felling were applied to 8β20-ha treatment plots at 11 sites across the Great Basin with a tree-shredding treatment also applied to four Utah sites. Treatments were applied across a tree infilling gradient as quantified by a covariate tree dominance index (TDI=tree cover/[tree+shrub+tall perennial grass cover]). Mixed model analysis of covariance indicated that treatment x covariate interactions were significant (P 0.4). Fire increased cheatgrass (Bromus tectorum L.) cover by an average of 4.2% for all values of TDI. Cutting or shredding trees generally produced similar responses and increased total perennial herbaceous and cheatgrass cover by an average of 10.2% and 3.8%, at TDIs β₯ 0.35 and β₯ 0.45. Cheatgrass cover estimated across the region was < 6% after treatment, but two warmer sites had high cheatgrass cover before (19.2% and 27.2%) and after tree reduction (26.6% and 50.4%). Fuel control treatments are viable management options for increasing understory cover across a range of sites and tree cover gradients, but should be accompanied by revegetation on warmer sites with depleted understories where cheatgrass is highly adapted. Shrub and perennial herbaceous cover can be maintained by mechanically treating at lower TDI. Perennial herbaceous cover is key for avoiding biotic and abiotic thresholds in this system through resisting weed dominance and erosion.Keywords: brush control, state and transition, prescribed fire, resilience, thresholds, mechanical treatments, masticatio
ΠΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΡΠΉ ΠΌΡΠ·ΡΠΊΠ°Π»ΡΠ½ΡΠΉ ΠΊΠΎΠ½ΠΊΡΡΡ Π² ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΠΈΠΌΠΈΠ΄ΠΆΠ° ΡΡΡΠ°Π½Ρ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ (Π½Π° ΠΏΡΠΈΠΌΠ΅ΡΠ΅ ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΡ 2017)
ΠΠ½Π½ΠΎΡΠ°ΡΠΈΡ Π²ΡΠΏΡΡΠΊΠ½ΠΎΠΉ ΠΊΠ²Π°Π»ΠΈΡΠΈΠΊΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ ΠΡΠ»ΠΎΠ² ΠΠΈΠΊΠΈΡΠ° Π‘Π΅ΡΠ³Π΅Π΅Π²ΠΈΡ Β«ΠΠΠΠΠ£ΠΠΠ ΠΠΠΠ«Π ΠΠ£ΠΠ«ΠΠΠΠ¬ΠΠ«Π ΠΠΠΠΠ£Π Π‘ Π Π€ΠΠ ΠΠΠ ΠΠΠΠΠΠ ΠΠΠΠΠΠ Π‘Π’Π ΠΠΠ« ΠΠ ΠΠΠΠΠΠΠΠ― (ΠΠ ΠΠ ΠΠΠΠ Π ΠΠΠ ΠΠΠΠΠΠΠΠ―-2017)Β» Π. ΡΡΠΊ. - ΠΡΠΊΠΎΠ²Π° ΠΠ»Π΅Π½Π° ΠΠ»Π°Π΄ΠΈΠΌΠΈΡΠΎΠ²Π½Π°, Π΄ΠΎΠΊΡΠΎΡ ΡΠΈΠ»ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π½Π°ΡΠΊ, Π΄ΠΎΡΠ΅Π½Ρ ΠΠ°ΡΠ΅Π΄ΡΠ° ΡΠ²ΡΠ·Π΅ΠΉ Ρ ΠΎΠ±ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΡΡΡΡ ΠΡΠ½Π°Ρ ΡΠΎΡΠΌΠ° ΠΎΠ±ΡΡΠ΅Π½ΠΈΡ ΠΠΊΡΡΠ°Π»ΡΠ½ΠΎΡΡΡ: ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΡΠΉ ΠΌΡΠ·ΡΠΊΠ°Π»ΡΠ½ΡΠΉ ΠΊΠΎΠ½ΠΊΡΡΡ ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΠ΅ ΠΊΠ°ΠΊ ΡΠ°ΠΌΠΎΠ΅ ΠΌΠ°ΡΡΡΠ°Π±Π½ΠΎΠ΅ ΡΠ΅Π³ΡΠ»ΡΡΠ½ΠΎΠ΅ Π²ΡΡΠΎΠΊΠΎΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ½ΠΎΠ΅ ΡΠ΅Π»Π΅Π²ΠΈΠ·ΠΈΠΎΠ½Π½ΠΎΠ΅ ΠΈ ΠΌΠ΅Π΄ΠΈΠ°-ΡΠΎΠ±ΡΡΠΈΠ΅, ΠΊΠΎΡΠΎΡΠΎΠ΅ . Π Π΅ΠΆΠ΅Π³ΠΎΠ΄Π½ΠΎ Π°ΠΊΡΠ΅Π½ΡΠΈΡΡΠ΅Ρ Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ Π°ΡΠ΄ΠΈΡΠΎΡΠΈΠΈ Π½Π° Π½Π°ΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎ-ΠΊΡΠ»ΡΡΡΡΠ½ΡΡ
ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΡΡ
ΡΡΡΠ°Π½Ρ-ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΎΡΠ° ΠΊΠΎΠ½ΠΊΡΡΡΠ°, ΡΠΎΡΠΌΠΈΡΡΠ΅Ρ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΡΠ΅ ΡΡΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΠΎΡΠΎΠΊΠΈ ΠΈ ΡΠ΅ΠΌ ΡΠ°ΠΌΡΠΌ ΡΠΏΠΎΡΠΎΠ±ΡΡΠ²ΡΠ΅Ρ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈΠΌΠΈΠ΄ΠΆΠ° ΡΠ΅ΡΡΠΈΡΠΎΡΠΈΠΈ. ΠΠΎΠ»Π΅Π΅ ΡΠΎΠ³ΠΎ, ΠΏΠΎΠ±Π΅Π΄Π° ΡΡΡΠ°Π½Ρ-ΡΡΠ°ΡΡΠ½ΠΈΡΡ ΠΊΠΎΠ½ΠΊΡΡΡΠ° ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΡ Π·Π°ΡΠ°ΡΡΡΡ ΠΎΡΡΠ°ΠΆΠ°Π΅Ρ ΠΈΠ΄Π΅ΠΎΠ»ΠΎΠ³ΠΎ-ΠΏΠΎΠ»ΠΈΡΠΈΡΠ΅ΡΠΊΠΈΠΉ Π²Π΅ΠΊΡΠΎΡ ΠΠ²ΡΠΎΠΏΡ ΠΈ ΠΏΠΎ ΡΡΡΠΈ Π΄Π΅Π»Π° Π²ΡΠΏΠΎΠ»Π½ΡΠ΅Ρ ΡΡΠ½ΠΊΡΠΈΡ ΠΏΠΎΠ»ΠΈΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ PR ΡΡΡΠ°Π½Ρ-ΠΏΠΎΠ±Π΅Π΄ΠΈΡΠ΅Π»Ρ ΠΈ ΡΡΡΠ°Π½Ρ-Ρ
ΠΎΠ·ΡΠΉΠΊΠΈ ΠΌΠ΅ΡΠΎΠΏΡΠΈΡΡΠΈΡ. Π‘Π»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎ Π°Π½Π°Π»ΠΈΠ· ΠΈΡΠΏΠΎΠ»ΡΠ·ΡΠ΅ΠΌΡΡ
Π½Π° ΠΌΠ΅ΡΠΎΠΏΡΠΈΡΡΠΈΠΈ ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠ²Π½ΡΡ
ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ ΡΠ²Π»ΡΠ΅ΡΡΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΡΠΌ ΠΈ Π²ΠΎΡΡΡΠ΅Π±ΠΎΠ²Π°Π½Π½ΡΠΌ Π΄Π»Ρ ΡΠΎΠ±ΡΡΠΈΠΉΠ½ΠΎΠ³ΠΎ ΠΈ ΡΡΡΡΠΎΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ PR ΠΠ±ΡΠ΅ΠΊΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ: ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠΎΠ½Π½ΡΠ΅ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΠΎΠ³ΠΎ ΠΌΡΠ·ΡΠΊΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΠΊΡΡΡΠ° (Π½Π° ΠΏΡΠΈΠΌΠ΅ΡΠ΅ ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΡ Π² ΠΠΈΠ΅Π²Π΅ Π² 2017 Π³.). ΠΡΠ΅Π΄ΠΌΠ΅Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ: ΡΡΠ½ΠΊΡΠΈΡ ΡΡΠ°ΡΡΡΠ½ΠΎΠ³ΠΎ PR-ΠΌΠ΅ΡΠΎΠΏΡΠΈΡΡΠΈΡ Π² ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΠΈΠΌΠΈΠ΄ΠΆΠ° ΡΡΡΠ°Π½Ρ. Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ: Π΄ΠΎΠΊΠ°Π·Π°ΡΡ, ΡΡΠΎ ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΡΠΉ ΠΌΡΠ·ΡΠΊΠ°Π»ΡΠ½ΡΠΉ ΠΊΠΎΠ½ΠΊΡΡΡ ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΠ΅ ΡΠΏΠΎΡΠΎΠ±ΡΡΠ²ΡΠ΅Ρ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈΠΌΠΈΠ΄ΠΆΠ° ΡΡΡΠ°Π½Ρ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ. ΠΠ°Π΄Π°ΡΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ: ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°ΡΡ ΡΠ΅ΡΠΌΠΈΠ½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΉ Π°ΠΏΠΏΠ°ΡΠ°Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ Π½Π°ΡΡΠ½ΠΎΠΉ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΡ ΠΏΠΎ ΠΈΠΌΠΈΠ΄ΠΆΠΌΠ΅ΠΉΠΊΠΈΠ½Π³Ρ, Π±ΡΠ΅Π½Π΄ΠΈΠ½Π³Ρ ΠΈ ΠΈΠ²Π΅Π½Ρ-ΠΌΠ΅Π½Π΅Π΄ΠΆΠΌΠ΅Π½ΡΡ; ΠΎΠΏΡΠ΅Π΄Π΅Π»ΠΈΡΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΡΠ΅ ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠΎΠ½Π½ΡΠ΅ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ, ΠΏΡΠΈΠΌΠ΅Π½ΡΠ΅ΠΌΡΠ΅ Π² ΡΠ°ΠΌΠΊΠ°Ρ
ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΡΡ
ΡΠΎΠ±ΡΡΠΈΠΉ Π΄Π»Ρ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈΠΌΠΈΠ΄ΠΆΠ° ΡΡΡΠ°Π½Ρ; ΠΎΠΏΠΈΡΠ°ΡΡ ΡΠΎΠ»Ρ ΠΠ²ΡΠΎΠΏΠ΅ΠΉΡΠΊΠΎΠ³ΠΎ ΠΠ΅ΡΠ°ΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ Π‘ΠΎΡΠ·Π° ΠΊΠ°ΠΊ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΎΡΠ° ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΡ Π² ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΠΈΠΌΠΈΠ΄ΠΆΠ° ΡΡΡΠ°Π½Ρ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ ΠΊΠΎΠ½ΠΊΡΡΡΠ°; ΠΎΡΠ΅Π½ΠΈΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΡΠ΅Π°Π»ΠΈΠ·ΠΎΠ²Π°Π½Π½ΡΡ
ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠ²Π½ΡΡ
ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈΠΌΠΈΠ΄ΠΆΠ° ΡΡΡΠ°Π½Ρ Π² ΡΠ°ΠΌΠΊΠ°Ρ
ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΡ; Π΄Π°ΡΡ ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°ΡΠΈΠΈ ΠΏΠΎ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈΠΌΠΈΠ΄ΠΆΠ° ΡΡΡΠ°Π½Ρ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΡ. Π’Π΅ΠΎΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠ°Ρ Π±Π°Π·Π°: Π½Π°ΡΡΠ½ΡΠ΅ ΡΡΡΠ΄Ρ Π. ΠΡΠΊΠΎΠ²ΠΎΠΉ, Π. ΠΠ°Π²ΡΡ, Π. ΠΠ°Π½ΠΊΡΡΡ
ΠΈΠ½Π°, Π. ΠΠΆΠ΅Π½Π΅ΡΠ°, Π. ΠΠ°Π²Π΅ΡΠΈΠ½ΠΎΠΉ, Π£. Π₯Π°Π»ΡΡΠ±Π°ΡΡΠ°, ΠΠΆ. ΠΠΎΠ»Π΄Π±Π»Π°ΡΡΠ° Π° ΡΠ°ΠΊΠΆΠ΅ ΡΡΡΠ΄Ρ Π. ΠΠ°ΡΡΠΌΠ°Π½Π° ΠΎ ΠΌΡΠ·ΡΠΊΠ°Π»ΡΠ½ΠΎΠΌ Π±ΠΈΠ·Π½Π΅ΡΠ΅, Π. ΠΠΆΠΎΡΠ΄Π°Π½Π° ΠΎ ΠΏΡΠΎΠ΄Π²ΠΈΠΆΠ΅Π½ΠΈΠΈ ΠΈΠΌΠΈΠ΄ΠΆΠ° ΡΡΡΠ°Π½ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΡ ΠΈ Π΄Ρ. ΠΠΌΠΏΠΈΡΠΈΡΠ΅ΡΠΊΠ°Ρ Π±Π°Π·Π°: PR-Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΡ, ΡΠ°Π·ΠΌΠ΅ΡΠ΅Π½Π½ΡΠ΅ Π½Π° ΡΠ°ΠΉΡΠ΅ ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΡ ΠΈ ΠΠ²ΡΠΎΠΏΠ΅ΠΉΡΠΊΠΎΠ³ΠΎ ΠΠ΅ΡΠ°ΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ Π‘ΠΎΡΠ·Π°; Π±ΠΎΠ»Π΅Π΅ ΠΏΠΎΠ»ΡΡΠΎΡΠ° ΠΌΠΈΠ»Π»ΠΈΠΎΠ½Π° ΡΡΠ°ΡΠ΅ΠΉ ΠΎΠ± Π£ΠΊΡΠ°ΠΈΠ½Π΅ Π² Π΅Π²ΡΠΎΠΏΠ΅ΠΉΡΠΊΠΈΡ
Π‘ΠΠ, ΡΠ°Π·ΠΌΠ΅ΡΠ΅Π½Π½ΡΠ΅ Π² Π±Π°Π·Π΅ ΠΏΡΠΎΠ΅ΠΊΡΠ° ΠΌΠΎΠ½ΠΈΡΠΎΡΠΈΠ½Π³Π° ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΠΎΠ³ΠΎ ΠΈΠΌΠΈΠ΄ΠΆΠ° Π£ΠΊΡΠ°ΠΈΠ½Ρ Β«OkoΒ»; Π΄Π°Π½Π½ΡΠ΅ Π±Π°Π·Ρ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»ΠΎΠ² Π‘ΠΠ ΠΈ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΡΡ
ΠΌΠ΅Π΄ΠΈΠ° Factiva; Π΄Π°Π½Π½ΡΠ΅ Google.Analytics. ΠΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠ°Ρ Π·Π½Π°ΡΠΈΠΌΠΎΡΡΡ: ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π΄ΠΎΠΊΠ°Π·ΡΠ²Π°Π΅Ρ, ΡΡΠΎ ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΡΠΉ ΠΌΡΠ·ΡΠΊΠ°Π»ΡΠ½ΡΠΉ ΠΊΠΎΠ½ΠΊΡΡΡ ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΠ΅ ΡΠΎΡΠΌΠΈΡΡΠ΅Ρ ΠΈΠΌΠΈΠ΄ΠΆ ΡΡΡΠ°Π½Ρ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ Π½Π΅Π·Π°Π²ΠΈΡΠΈΠΌΠΎ ΠΎΡ ΡΡΠΏΠ΅ΡΠ½ΠΎΡΡΠΈ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ ΠΊΠΎΠ½ΠΊΡΠ΅ΡΠ½ΡΡ
ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈΠΌΠΈΠ΄ΠΆΠ° ΡΡΡΠ°Π½Ρ. Π’Π΅Π·ΠΈΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π±ΡΠ»ΠΈ Π°ΠΏΡΠΎΠ±ΠΈΡΠΎΠ²Π°Π½Ρ Π½Π° ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΠΎΠΌ Π½Π°ΡΡΠ½ΠΎΠΌ ΡΠΎΡΡΠΌΠ΅ Β«ΠΠ΅Π΄ΠΈΠ° Π² ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΌ ΠΌΠΈΡΠ΅. 57-Π΅ ΠΠ΅ΡΠ΅ΡΠ±ΡΡΠ³ΡΠΊΠΈΠ΅ ΡΡΠ΅Π½ΠΈΡΒ», ΠΎΠΏΡΠ±Π»ΠΈΠΊΠΎΠ²Π°Π½Ρ Π² ΡΠ±ΠΎΡΠ½ΠΈΠΊΠ΅ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»ΠΎΠ² ΡΡΠ°ΡΠ΅ΠΉ ΡΠΎΡΡΠΌΠ° ΠΈ ΠΈΠΌΠ΅ΡΡ ΡΡΠ°ΡΡΡ Π½Π°ΡΡΠ½ΠΎΠΉ ΡΡΠ°ΡΡΠΈ, ΡΠ°Π·ΠΌΠ΅ΡΠ΅Π½Π½ΠΎΠΉ Π² Π±Π°Π·Π΅ Π ΠΠΠ¦. Π‘ΡΡΡΠΊΡΡΡΠ° ΡΠ°Π±ΠΎΡΡ: Π Π°Π±ΠΎΡΠ° ΡΠΎΡΡΠΎΠΈΡ ΠΈΠ· Π²Π²Π΅Π΄Π΅Π½ΠΈΡ, 3 Π³Π»Π°Π²: Β«ΡΡΠ½ΠΊΡΠΈΡ ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠΎΠ±ΡΡΠΈΡ Π² ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΠΈΠΌΠΈΠ΄ΠΆΠ° ΡΡΡΠ°Π½ΡΒ», Β«ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΠ΅ ΠΊΠ°ΠΊ ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠ΅ ΡΠΎΠ±ΡΡΠΈΠ΅ ΠΠ²ΡΠΎΠΏΠ΅ΠΉΡΠΊΠΎΠ³ΠΎ ΠΠ΅ΡΠ°ΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ Π‘ΠΎΡΠ·Π°Β» ΠΈ Β«ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠΎΠ½Π½ΡΠΉ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π» ΠΠ²ΡΠΎΠ²ΠΈΠ΄Π΅Π½ΠΈΡ ΠΊΠ°ΠΊ ΠΏΠ»ΠΎΡΠ°Π΄ΠΊΠΈ Π΄Π»Ρ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈΠΌΠΈΠ΄ΠΆΠ° ΡΡΡΠ°Π½ΡΒ», Π·Π°ΠΊΠ»ΡΡΠ΅Π½ΠΈΡ, ΡΠΏΠΈΡΠΊΠ° ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½Π½ΠΎΠΉ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΡ ΠΈΠ· 67 ΠΏΠΎΠ·ΠΈΡΠΈΠΉ ΠΈ 12 ΠΏΡΠΈΠ»ΠΎΠΆΠ΅Π½ΠΈΠΉ. ΠΠ±ΡΠΈΠΉ ΠΎΠ±ΡΠ΅ΠΌ 76 ΡΡΡΠ°Π½ΠΈΡ.Abstract of graduating qualification thesis Mikita Arlou INTERNATIONAL MUSIC CONTEST IN HOST COUNTRY IMAGE FORMATION (ON THE EXAMPLE OF EUROVISION 2017) Supervisor associate professor Elena Bykova, doctor of philology Department of PR in business full-time study Relevance: the international music contest Eurovision as the most wide scale regular high tech TV and Media event which annually emphasizes audience attention on national cultural features of the host country, forms tourist flows which have huge influence on territorial image formation. Besides the win of a participating in the Eurovision country often shows the ideological and political European vector and in fact serves as political PR of the winning or host country. Consequently the analysis of applied communication technologies is relevant and in-demand for event PR. Research object: communication activities of international music contest (on the example of Eurovision in Kyiv in 2017). Research subject: function of status PR event in country image formation. The aim of research: to prove that international music contest Eurovision contributes host country image formation. The tasks of research: to develop research terminology based on scientific literature on image making, branding and event management; to define actual communication technologies applied in special PR events on country image formation; to describe European Broadcasting Union role in host country image formation; to appreciate effectiveness of applied communication technologies on host country image formation in Eurovision; to give recommendations for host country image formation with the help of Eurovision. Theoretical base: scientific works written by E. Bykova, D. Gavra, A. Pankrukhin, B. Jenes, E. Kaverina, U. Halcbaur, J. Goldblatt and D. PassmanΒ΄s works on music business and P. Jordan on county image building with the help of Eurovision, etc. The empirical base: PR documents from official Eurovision and European Broadcasting Union websites; more than 1.5 million articles on Ukraine in European media stored in the base of international Ukrainian image monitoring project Oko; content of the mass media and social media base Factiva; Google.Analytics data. Practical significance: the research proves that international music contest Eurovision is relevant for the host country image formation independently of the success level of applied country image formation communication technologies. Approbation: General positions of current thesis were aprobated on international scientific forum Media in modern world and were published at the collection of articles of the forum and have the status of a scientific article posted in the RINC database. Thesis structure: Research consists of introduction, 3 chapters: Special event function in country image formation, Eurovision as EBU special event and communication potential of Eurovision as a platform for image formation; conclusion, literature list from 67 positions and 12 attachments. The total volume is 76 pages
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