3 research outputs found
Efficient CRISPR/Cas9-Mediated Gene Knock-In in Mouse Hematopoietic Stem/Progenitor Cells
Additional file 1: Figure S1. of Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes
CRISPR/Cas9 induced DSBs at the Rosa26 intronic XbaI site in mouse zygotes; Figure S2: Sequence analysis of founder derived PCR products. Figure S3: Analysis of off-target activity. (DOC 1735 kb