342 research outputs found

    A documentary study of the felt effects of the great California earthquake of 1857

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    We have collected over 60 hitherto unpublished accounts of the California earthquake of January 9, 1857. We have used them, together with those already known, to estimate felt intensities and prepare an isoseismal map which roughly indicates the level of short-period ground motion experienced during this earthquake. Modified Mercalli intensities of VI to VII occurred in the modern metropolitan areas of southern California, and VI to VIII in the southern San Joaquin Valley. The intensity along the fault was IX or more. Instances of seiching, fissuring, sandblows, and hydrologic changes were reported from Sacramento to the Colorado River delta. Most reports say that shaking lasted between one and three minutes. At least two large aftershocks occurred within a week of the main event

    Distributed collaboration between industry and university partners in HE

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    Over the past three years the School of Design has been experimenting with an innovative curriculum design and delivery model named β€˜the Global Studio’. The Global Studio is a cross-institutional research informed teaching and learning collaboration conducted between Northumbria University and international universities and industry partners based in the UK, USA, Netherlands and Korea. The aims of the Global Studio are directly linked with current and future industry needs that are related to changes in the organisation of product and service development. These changes highlight the importance of equipping design students with skills for working in globally networked organisations particularly the development of skills in intercultural communication and collaboration. In this paper we will focus on the Global Studio conducted in 2008 which included Northumbria University (UK), Hongik University (Korea), Auburn University (USA), Intel (USA), Motorola design studios located in the UK and Korea and Great Southern Wood (USA). These projects will be used to illustrate challenges and benefits of international collaborative industry-based projects undertaken in distributed settings

    Surface contamination of cars : a review

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    This review surveys the problem of surface contamination for cars, which poses a growing engineering challenge to vehicle manufacturers, operators and users. Both drivers’ vision and vehicle visibility need to be maintained under a wide range of environmental conditions. This requires managing the flow of surface water on wind screens and side glazing. The rate of deposition of solid contaminants on glazing, lights, license plates and external mirrors also needs to be minimised. Maintaining vehicle aesthetics and limiting the transfer of contaminants to the hands and clothes of users from soiled surfaces are also significant issues. Recently, keeping camera lenses clean has emerged as a key concern, as these systems transition from occasional manoeuvring aids to sensors for safety systems. The deposition of water and solid contaminants onto car surfaces is strongly influenced by unsteady vehicle aerodynamic effects. Airborne water droplets falling as rain or lifted as spray by tyres interact with wakes, vortices and shear flows and accumulate on vehicle surfaces as a consequence. The same aerodynamic effects also control the movement of surface water droplets, rivulets and films; hence, particular attention is paid to surface water management over the front side-glass and the deposition of contaminants on the rear surfaces. The test methods used in the automotive industry are reviewed, as are numerical simulation techniques

    Uplift and subsidence associated with the great Aceh-Andaman earthquake of 2004

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    Rupture of the Sunda megathrust on 26 December 2004 produced broad regions of uplift and subsidence. We define the pivot line separating these regions as a first step in defining the lateral extent and the downdip limit of rupture during that great M_w β‰ˆ 9.2 earthquake. In the region of the Andaman and Nicobar islands we rely exclusively on the interpretation of satellite imagery and a tidal model. At the southern limit of the great rupture we rely principally on field measurements of emerged coral microatolls. Uplift extends from the middle of Simeulue Island, Sumatra, at ~2.5Β°N, to Preparis Island, Myanmar (Burma), at ~14.9Β°N. Thus the rupture is ~1600 km long. The distance from the pivot line to the trench varies appreciably. The northern and western Andaman Islands rose, whereas the southern and eastern portion of the islands subsided. The Nicobar Islands and the west coast of Aceh province, Sumatra, subsided. Tilt at the southern end of the rupture is steep; the distance from 1.5 m of uplift to the pivot line is just 60 km. Our method of using satellite imagery to recognize changes in elevation relative to sea surface height and of using a tidal model to place quantitative bounds on coseismic uplift or subsidence is a novel approach that can be adapted to other forms of remote sensing and can be applied to other subduction zones in tropical regions

    Perceived environment and physical activity: a meta-analysis of selected environmental characteristics

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    BACKGROUND: Several narrative reviews have been conducted on the literature examining environmental correlates of physical activity (PA). To date these reviews have been unable to provide definitive summaries of observed associations. This study utilizes meta-analytical techniques to calculate summaries of associations between selected environmental characteristics and PA. METHODS: Published studies were identified from electronic databases and searches of personal files. Studies were examined to determine the environmental constructs most frequently studied. Included studies (N = 16) examined at least one identified construct and determined associations between perceived environmental constructs and PA using logistic regression. Data were analyzed separately for crude and adjusted ORs using general-variance based fixed effect models. RESULTS: No significant associations emerged between environmental characteristics and PA using crude OR. The perceived presence of PA facilities (OR 1.20, 95% 1.06–1.34), sidewalks (OR 1.23, 95% 1.13–1.32), shops and services (OR 1.30, 95% 1.14–1.46) and perceiving traffic not to be a problem (OR 1.22, 95% 1.08–1.37) were positively associated with activity using adjusted ORs. Variance in PA accounted for by significant associations ranged from 4% (heavy traffic not a problem) to 7% (presence of shops and services). CONCLUSION: Results of the meta-analysis support the relevance of perceived environmental characteristics for understanding population PA. These results should encourage the use of comprehensive ecological models that incorporate variables beyond basic demographic information

    Simulation of rear surface contamination for a simple bluff body

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    Predicting the accumulation of material on the rear surfaces of square-backed cars is important to vehicle manufacturers, as this progressively compromises rear vision, vehicle visibility and aesthetics. It also reduces the effectiveness of rear mounted cameras. Here, this problem is represented by a simple bluff body with a single sprayer mounted centrally under its rear trailing edge. A Very Large Eddy Simulation (VLES) solver is used to simulate both the aerodynamics of the body and deposition of contaminant. Aerodynamic drag and lift coefficients were predicted to within +1.3% and βˆ’4.2% of their experimental values, respectively. Wake topology was also correctly captured, resulting in a credible prediction of the rear surface deposition pattern. Contaminant deposition is mainly driven by the lower part of the wake ring vortex, which advects material back onto the rear surface. This leads to a maximum below the rear stagnation point and an association with regions of higher base pressure. The accumulation of mass is linear with time; the relative distribution changing little as the simulation progresses, implying that shorter simulations can be compared to longer experiments. Further, the rate of accumulation quickly reaches a settled mean value, suggesting utility as a metric for assessing different vehicles

    Multi-exon COL5A1 deletion in a child with classical Ehlers-Danlos syndrome : A case report expanding the allelic spectrum and showing evidence of parental gonosomal mosaicism

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    Classical Ehlers-Danlos syndrome (cEDS) is a rare inherited autosomal dominant connective tissue disorder with core clinical features including skin hyperextensibility, abnormal scarring, and generalized joint hypermobility. Classical EDS is predominantly caused by small pathogenic variants in the genes COL5A1 and COL5A2 and occasionally by a COL1A1 point mutation p.(Arg312Cys), while gross deletions or duplications are uncommon. Gonosomal mosaicism is thought to be exceedingly rare with only two cases reported in the literature. We report a child with cEDS due to a rare gross deletion of exons 2-65 in the COL5A1 gene, inherited from an unaffected mosaic father. The level of mosaicism in the father was approximately 43% in leucocyte cells and 30% in DNA extracted from skin. Our results expand the allelic spectrum of cEDS variants and suggest that parental mosaicism needs to be considered in patients with suspected cEDS, given its implication for genetic counseling.Peer reviewe

    Coordinated Spindle Assembly and Orientation Requires Clb5p-Dependent Kinase in Budding Yeast

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    The orientation of the mitotic spindle along a polarity axis is critical in asymmetric cell divisions. In the budding yeast, Saccharomyces cerevisiae, loss of the S-phase B-type cyclin Clb5p under conditions of limited cyclin-dependent kinase activity (cdc28-4 clb5Ξ” cells) causes a spindle positioning defect that results in an undivided nucleus entering the bud. Based on time-lapse digital imaging microscopy of microtubules labeled with green fluorescent protein fusions to either tubulin or dynein, we observed that the asymmetric behavior of the spindle pole bodies during spindle assembly was lost in the cdc28-4 clb5Ξ” cells. As soon as a spindle formed, both poles were equally likely to interact with the bud cell cortex. Persistent dynamic interactions with the bud ultimately led to spindle translocation across the bud neck. Thus, the mutant failed to assign one spindle pole body the task of organizing astral microtubules towards the mother cell. Our data suggest that Clb5p-associated kinase is required to confer mother-bound behavior to one pole in order to establish correct spindle polarity. In contrast, B-type cyclins, Clb3p and Clb4p, though partially redundant with Clb5p for an early role in spindle morphogenesis, preferentially promote spindle assembly
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