Sleep restriction increases white blood cells, mainly neutrophil count, in young healthy men: A pilot study

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Temporal Dissociation between Myeloperoxidase (MPO)-Modified LDL and MPO Elevations during Chronic Sleep Restriction and Recovery in Healthy Young Men

OBJECTIVES: Many studies have evaluated the ways in which sleep disturbances may influence inflammation and the possible links of this effect to cardiovascular risk. Our objective was to investigate the effects of chronic sleep restriction and recovery on several blood cardiovascular biomarkers. METHODS AND RESULTS: Nine healthy male non-smokers, aged 22-29 years, were admitted to the Sleep Laboratory for 11 days and nights under continuous electroencephalogram polysomnography. The study consisted of three baseline nights of 8 hours sleep (from 11 pm to 7 am), five sleep-restricted nights, during which sleep was allowed only between 1 am and 6 am, and three recovery nights of 8 hours sleep (11 pm to 7 am). Myeloperoxidase-modified low-density lipoprotein levels increased during the sleep-restricted period indicating an oxidative stress. A significant increase in the quantity of slow-wave sleep was measured during the first recovery night. After this first recovery night, insulin-like growth factor-1 levels increased and myeloperoxidase concentration peaked. CONCLUSIONS: We observed for the first time that sleep restriction and the recovery process are associated with differential changes in blood biomarkers of cardiovascular disease

EEG sleep in non-affective psychiatric disorders

Several sleep complaints and disturbances have been documented in psychiatric disorders. These modifications of sleep in anxiety disorders, alcoholism, schizophrenia, dementia and eating disorders are reviewed and discussed. At the present time, there is no evidence for any specific sleep pattern in nonaffective psychiatric disorders. The co-morbidity of sleep disorders like sleep apnoea, periodic leg movements and parasomnia in psychiatric illness is not very well known at the present time.SCOPUS: re.jinfo:eu-repo/semantics/publishe

INTERET DES ETUDES EEG DE SOMMEIL DANS LA DEPRESSION

SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

Sleep electroencephalography in depressive illness. A collaborative study by the World Health Organization

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Sleep and Memory

info:eu-repo/semantics/nonPublishe

Age modulates the effects of sleep restriction in women

Study Objectives: To investigate how age influences the effects of 3 nights of sleep restriction in healthy women. Design: After a baseline night, sleep was restricted to 4 hours during 3 consecutive nights. One recovery night followed the sleep restriction. Setting: The sleep-restriction experiments were conducted under standardized conditions with continuous electroencephalographic ambulatory recordings. Before entering the study, the subjects underwent a polysomnographic recording for exclusion of sleep disorder and adaptation to the laboratory environment. Participants: Eleven young women (aged 20-30 years) and 10 older women (aged 55-65 years) were included in the study. Intervention: The subjects were admitted to the sleep laboratory for 5 consecutive nights and days. After 1 baseline night, 3 nights of sleep restriction to 4 hours were performed and were followed by 1 recovery night of 8 hours. Continuous ambulatory electroencephalographic recordings were performed, as well as the Maintenance of Wakefulness Test (8:30 AM and 1:30 PM), the Stanford Sleepiness Scale, and the Psychomotor Vigilance Test. Results: Young women were more affected by sleep restriction than were the older women. This was evidenced by more sleep onsets during the Maintenance of Wakefulness Test sessions in the young subjects, who also rated themselves more sleepy than the older women. Conclusions: Age influences the impact of sleep restriction on vigilance in women.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

The effects of antidepressant treatment on sleep disturbances in depression

Sleep problems are classical complaints in depressed patients. Polygraphie recordings performed in drug free depressed patients during an acute episode of the illness have allowed description of sleep continuity, architecture and REM sleep disturbances. While the specificity of these abnormalities is not fully established, these perturbations appear to be core symptoms of the depressive episode. Antidepressants drugs, whatever their pharmacological profile have been shown to suppress or at least to reduce REM sleep. However, the effects of these drugs on sleep continuity and architecture seem to be related to their specific pharmacological action. © 1995 Elsevier, Paris.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Implicit memory and Rapid Eye Movement sleep

info:eu-repo/semantics/nonPublishe