5,145 research outputs found
TRUSTWORTHINESS AS AN ECONOMIC ASSET
The evaluation of trust in economic decision making remains on the periphery of mainstream economic analysis and teaching. Yet business managers use trustworthiness in daily exchanges to create competitive advantages for their firms. An exploratory empirical test of Barney and HansenÂ’s three levels of trust (weak, semistrong, and strong) and Lewicki and BunkerÂ’s portfolio of governance mechanisms revealed that strong-form trust exists in day-to-day business relationships along with other governance mechanisms. Identity-based transactions were more prevalent than were weak trust market exchanges in important economic transactions.Institutional and Behavioral Economics, International Relations/Trade,
Dephasing dynamics of Rydberg atom spin waves
A theory of Rydberg atom interactions is used to derive analytical forms for
the spin wave pair correlation function in laser-excited cold-atom vapors. This
function controls the quantum statistics of light emission from dense,
inhomogeneous clouds of cold atoms of various spatial dimensionalities. The
results yield distinctive scaling behaviors on the microsecond timescale,
including generalized exponential decay. A detailed comparison is presented
with a recent experiment on a cigar-shaped atomic ensemble [Y. Dudin and A.
Kuzmich, Science 336, 887 (2012)], in which Rb atoms are excited to a set of
Rydberg levels.Comment: 4 pages, Supplemental Material in Appendix, 4 figure
Images in cardiovascular medicine : multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery
Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial lymphoid-like tissues.1,2 These results suggest that lymphocyte responses in the lamina adventitia may play a crucial role in atherosclerosis development.1,
ALMA and Keck analysis of Fomalhaut field sources: JWST's Great Dust Cloud is a background object
At 7.7 pc, the A-type star Fomalhaut hosts a bright debris disk with multiple
radial components. The disk is eccentric and misaligned, strongly suggesting
that it is sculpted by interaction with one or more planets. Compact sources
are now being detected with JWST, suggesting that new planet detections may be
imminent. However, to confirm such sources as companions, common proper motion
with the star must be established, as with unprecedented sensitivity comes a
high probability that planet candidates are actually background objects. Here,
ALMA and Keck observations of Fomalhaut are found to show significant emission
at the same sky location as multiple compact sources in JWST MIRI coronagraphic
observations, one of which has been dubbed the "Great Dust Cloud" because it
lies within the outer belt. Since the ground-based data were obtained between 6
to 18 years prior to the JWST observations, these compact sources are unlikely
to be common proper motion companions to Fomalhaut. More generally, this work
illustrates that images collected at a range of wavelengths can be valuable for
rejecting planet candidates uncovered via direct imaging with JWST.Comment: MNRAS in pres
Primary Corrosion Processes for Polymer-Embedded Free-Standing or Substrate-Supported Silicon Microwire Arrays in Aqueous Alkaline Electrolytes
Solar fuel devices have shown promise as a sustainable source of chemical fuels. However, long-term stability of light absorbing materials remains a substantial barrier to practical devices. Herein, multiple corrosion pathways in 1 M KOH(aq) have been defined for TiOâ‚‚-protected Si microwire arrays in a polymer membrane either attached to a substrate or free-standing. Top-down corrosion was observed in both morphologies through defects in the TiOâ‚‚ coating. For the substrate-based samples, bottom-up corrosion was observed through the substrate and up the adjacent wires. In the free-standing samples, uniform bottom-up corrosion was observed through the membrane with all wire material corroded within 10 days of immersion in the dark in 1 M KOH(aq)
HIV-1 Coreceptor Activity of CCR5 and Its Inhibition by Chemokines: Independence from G Protein Signaling and Importance of Coreceptor Downmodulation
AbstractHIV-1 infection requires the presence of specific chemokine receptors on CD4+ target cells to enable the fusion reactions involved in virus entry. CCR5 is a major fusion coreceptor for macrophage-tropic HIV-1 isolates. HIV-1 entry and fusion are mediated by the viral envelope glycoprotein (Env) and are inhibited by CCR5 ligands, but the mechanisms are unknown. Here, we test the role of G protein signaling and CCR5 surface downmodulation by two separate approaches: direct inactivation of CCR5 signaling by mutagenesis and inactivation of Gi-type G proteins with pertussis toxin. A CCR5 mutant lacking the last 45 amino acids of the cytoplasmic C-terminus (CCR5306) was created that was expressed on transfected cells at levels comparable to cells expressing CCR5 and displayed normal chemokine binding affinity. CCR5 ligands induced calcium flux and receptor downmodulation in cells expressing CCR5, but not in cells expressing CCR5306. Nevertheless, CCR5 or CCR5306, when coexpressed with CD4, supported comparable HIV-1 Env-mediated cell fusion. Consistent with this, treatment of CCR5-expressing cells with pertussis toxin completely blocked ligand-induced transient calcium flux, but did not affect Env-mediated cell fusion or HIV-1 infection. Also, pertussis toxin did not block chemokine inhibition of Env-mediated cell fusion or HIV-1 infection. However, chemokines inhibited Env-mediated cell fusion less efficiently for CCR5306than for CCR5. We conclude that the C-terminal domain of CCR5 is critical for G protein signaling and receptor downmodulation from the surface, but that neither function is required for CCR5 fusion coreceptor activity. The contrasting phenotypes of CCR5 and CCR5306suggest that coreceptor downmodulation and direct blockage of Env interaction sites both contribute to chemokine inhibition of HIV-1 infection
Transport and Use of a Centaur Second Stage in Space
As nations continue to explore space, the desire to reduce costs will continue to grow. As a method of cost reduction, transporting and/or use of launch system components as integral components of missions may become more commonplace in the future. There have been numerous scenarios written for using launch vehicle components (primarily space shuttle used external tanks) as part of flight missions or future habitats. Future studies for possible uses of launch vehicle upper stages might include asteroid diverter using gravity orbital perturbation, orbiting station component, raw material at an outpost, and kinetic impactor. The LCROSS (Lunar CRater Observation and Sensing Satellite) mission was conceived as a low-cost means of determining whether water exists at the polar regions of the moon. Manifested as a secondary payload with the LRO (Lunar Reconnaissance Orbiter) spacecraft aboard an Atlas V launch vehicle, LCROSS guided its spent Centaur Earth Departure Upper Stage (EDUS) into the lunar crater Cabeu's, as a kinetic impactor. This paper describes some of the challenges that the LCROSS project encountered in planning, designing, launching with and carrying the Centaur upper stage to the moon
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