New design method of FIR filters with SP2 coefficients based on a new linear programming relaxation with triangle inequalities

Publication in the conference proceedings of EUSIPCO, Toulouse, France, 200

Sympathetic stimulation produces a greater increase in both transmural and spatial dispersion of repolarization in LQT1 than LQT2 forms of congenital long QT syndrome

AbstractOBJECTIVESThe study compared the influence of sympathetic stimulation on transmural and spatial dispersion of repolarization between LQT1 and LQT2 forms of congenital long QT syndrome (LQTS).BACKGROUNDCardiac events are more associated with sympathetic stimulation in LQT1 than in LQT2 or LQT3 syndrome. Experimental studies have suggested that the interval between Tpeak and Tend (Tp-e) in the electrocardiogram (ECG) reflects transmural dispersion of repolarization across the ventricular wall.METHODSWe recorded 87-lead body-surface ECGs before and after epinephrine infusion (0.1 μg/kg/min) in 13 LQT1, 6 LQT2, and 7 control patients. The Q-Tend (QT-e), Q-Tpeak (QT-p), and Tp-e were measured automatically from 87-lead ECGs, corrected by Bazett’s method (QTc-e, QTc-p, Tcp-e), and averaged among all 87-leads and among 24-leads, which reflect the potential from the left ventricular free wall. As an index of spatial dispersion of repolarization, the dispersion of QTc-e (QTc-eD) and QTc-p (QTc-pD) were obtained among 87-leads and among 24-leads, and were defined as the interval between the maximum and the minimum of the QTc-e and the QTc-p, respectively.RESULTSEpinephrine significantly increased the mean QTc-e but not the mean QTc-p, resulting in a significant increase in the mean Tcp-e in both LQT1 and LQT2, but not in control patients. The epinephrine-induced increases in the mean QTc-e and Tcp-e were larger in LQT1 than in LQT2, and were more pronounced when the averaged data were obtained from 24-leads than from 87-leads. Epinephrine increased the maximum QTc-e but not the minimum QTc-e, producing a significant increase in the QTc-eD in both LQT1 and LQT2 patients, but not in control patients. The increase in the QTc-eD was larger in LQT1 than in LQT2 patients.CONCLUSIONSOur data suggest that sympathetic stimulation produces a greater increase in both transmural and spatial dispersion of repolarization in LQT1 than in LQT2 syndrome, and this may explain why LQT1 patients are more sensitive to sympathetic stimulation

Differential effects of beta-blockade on dispersion of repolarization in the absence and presence of sympathetic stimulation between the lqt1 and lqt2 forms of congenital long qt syndrome

AbstractObjectivesThis study compared the effects of beta-blockade on transmural and spatial dispersion of repolarization (TDR and SDR, respectively) between the LQT1 and LQT2 forms of congenital long QT syndrome (LQTS).BackgroundThe LQT1 form is more sensitive to sympathetic stimulation and more responsive to beta-blockers than either the LQT2 or LQT3 forms.MethodsEighty-seven-lead, body-surface electrocardiograms (ECGs) were recorded before and after epinephrine infusion (0.1 μg/kg body weight per min) in the absence and presence of oral propranolol (0.5–2.0 mg/kg per day) in 11 LQT1 patients and 11 LQT2 patients. The Q-Tendinterval, the Q-Tpeakinterval and the interval between Tpeakand Tend(Tp-e), representing TDR, were measured and averaged from 87-lead ECGs and corrected by Bazett’s method (corrected Q-Tendinterval [cQTe], corrected Q-Tpeakinterval [cQTp] and corrected interval between Tpeakand Tend[cTp-e]). The dispersion of cQTe(cQTe-D) was obtained among 87 leads and was defined as the interval between the maximum and minimum values of cQTe.ResultsPropranolol in the absence of epinephrine significantly prolonged the mean cQTpvalue but not the mean cQTevalue, thus decreasing the mean cTp-evalue in both LQT1 and LQT2 patients; the differences with propranolol were significantly larger in LQT1 than in LQT2 (p < 0.05). The maximum cQTe, minimum cQTeand cQTe-D were not changed with propranolol. Propranolol completely suppressed the influence of epinephrine in prolonging the mean cQTe, maximum cQTeand minimum cQTevalues, as well as increasing the mean cTp-eand cQTe-D values in both groups.ConclusionsBeta-blockade under normal sympathetic tone produces a greater decrease in TDR in the LQT1 form than in the LQT2 form, explaining the superior effectiveness of beta-blockers in LQT1 versus LQT2. Beta-blockers also suppress the influence of sympathetic stimulation in increasing TDR and SDR equally in LQT1 and LQT2 syndrome

Brane-Antibrane Systems at Finite Temperature and Phase Transition near the Hagedorn Temperature

In order to study the thermodynamic properties of brane-antibrane systems, we compute the finite temperature effective potential of tachyon T in this system on the basis of boundary string field theory. At low temperature, the minimum of the potential shifts towards T=0 as the temperature increases. In the D9-antiD9 case, the sign of the coefficient of |T|^2 term of the potential changes slightly below the Hagedorn temperature. This means that a phase transition occurs near the Hagedorn temperature. On the other hand, the coefficient is kept negative in the Dp-antiDp case with p <= 8, and thus a phase transition does not occur. This leads us to the conclusion that only a D9-antiD9 pair and no other (lower dimensional) brane-antibrane pairs are created near the Hagedorn temperature. We also discuss a phase transition in NS9B-antiNS9B case as a model of the Hagedorn transition of closed strings.Comment: 28 pages, 3 figures, minor errors correcte

Finite Temperature Systems of Brane-Antibrane on a Torus

In order to study the thermodynamic properties of brane-antibrane systems in the toroidal background, we compute the finite temperature effective potential of tachyon T in this system on the basis of boundary string field theory. We first consider the case that all the radii of the target space torus are about the string scale. If the Dp-antiDp pair is extended in all the non-compact directions, the sign of the coefficient of |T|^2 term of the potential changes slightly below the Hagedorn temperature. This means that a phase transition occurs near the Hagedorn temperature. On the other hand, if the Dp-antiDp pair is not extended in all the non-compact directions, the coefficient is kept negative, and thus a phase transition does not occur. Secondly, we consider the case that some of the radii of the target space torus are much larger than the string scale and investigate the behavior of the potential for each value of the radii and the total energy. If the Dp-antiDp pair is extended in all the non-compact directions, a phase transition occurs for large enough total energy.Comment: 23 pages, 3 figures, minor errors corrected, version to appear in JHE

Age and growth of Pacific saury Cololabis saira (Brevoort) in the western North Pacific Ocean estimated from daily otolith growth increments

Growth of Pacific saury Cololabis saira (Brevoort) inhabiting the western North Pacific wasstudied based on counting daily growth increments with a scanning electron microscope (SEM). The small-size group (knob length: 200-240mm), medium-size group (knob length: 240-280mm) and largesize group (knob length: >280mm) showed increments of 256±26.0 (S. D.), 405±76.1 and 566±48.2, respectively. Based on daily growth increment formation, we determined that the ages of the 3 groups were about 8, 13, and 19 months. Small- and large-size fish were considered tohave been hatched from autumn to winter, and medium-size fish from spring to summer. The oldest specimen of Pacific saury examined in this study was about 23 months of age; thus, the lifespan of Pacific saury in this area seems to be at least 1.5 years