Humility, trauma, and solidarity : the rhetoric of sensitivity

Humility, Trauma, and Solidarity: The Rhetoric of Sensitivity enters a conversation in rhetorical studies about the agency, effectivity, and conditions of possibility for the rhetorical subject. This project is an exploration in several registers of the preoriginary affectability that Diane Davis has called "rhetoricity." Rhetoricity exposes existents to affection from outside in a structure of addressivity that is fundamentally rhetorical. Prior to individuation as a subject, rhetoricity implies that beings are differentiated first through response to an address or call. This extra-symbolic affection brings one into being as the subject of a rhetorical relation. This project aims to inscribe the valences of rhetoricity: its traumatic force, and even violence, but also its generation of the possibility for becoming otherwise. These valences are charted through chapters on reading and addiction, sensitivity, and identification in hypertext video games. In "Addiction, Humility, and Rhetoricity," I explore the uncontrollable relationality of addiction through a reading of David Foster Wallace's novel Infinite Jest. I argue that an addictive habit, even reading habits, indicate the radical affectability of the subject. Rhetorical exposedness is a route of access to one's interiority that cannot be totally blocked off. The next chapter examines the public controversy over the use of trigger warnings in college classes. "Sensitive Students" argues that students' experiences of trauma mark an exposition to affection that makes teaching possible. In the final chapter, "Twisted Together: Twine Games and Solidarity," I argue that a set of hypertext video games made by transgender women are contesting the dominant values of gamer culture. By confronting players with an alterity internal to identification, these games erode the centrality of identification to rhetoric and forward solidarity as a shared relation to difference instead. This project traces the ways that gender marks and even constitutes the rhetorical structure of address. Sensitivity, receptivity, and exposedness are sites of gendering marks that persist and reverberate into the very formation of the rhetorical subject. This project opens a way for rhetoricians to frame exposedness as a rhetorical moment of ethicity: as being outside oneself, being beside oneself, and being for others.Englis

Shedding Light on the Galaxy Luminosity Function

From as early as the 1930s, astronomers have tried to quantify the statistical nature of the evolution and large-scale structure of galaxies by studying their luminosity distribution as a function of redshift - known as the galaxy luminosity function (LF). Accurately constructing the LF remains a popular and yet tricky pursuit in modern observational cosmology where the presence of observational selection effects due to e.g. detection thresholds in apparent magnitude, colour, surface brightness or some combination thereof can render any given galaxy survey incomplete and thus introduce bias into the LF. Over the last seventy years there have been numerous sophisticated statistical approaches devised to tackle these issues; all have advantages -- but not one is perfect. This review takes a broad historical look at the key statistical tools that have been developed over this period, discussing their relative merits and highlighting any significant extensions and modifications. In addition, the more generalised methods that have emerged within the last few years are examined. These methods propose a more rigorous statistical framework within which to determine the LF compared to some of the more traditional methods. I also look at how photometric redshift estimations are being incorporated into the LF methodology as well as considering the construction of bivariate LFs. Finally, I review the ongoing development of completeness estimators which test some of the fundamental assumptions going into LF estimators and can be powerful probes of any residual systematic effects inherent magnitude-redshift data.Comment: 95 pages, 23 figures, 3 tables. Now published in The Astronomy & Astrophysics Review. This version: bring in line with A&AR format requirements, also minor typo corrections made, additional citations and higher rez images adde

Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) inhibits inflammasome-mediated inflammation and has been proposed as a treatment for patients hospitalised with COVID-19. This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple treatments in patients hospitalised for COVID-19 (NCT04381936, ISRCTN50189673). In this assessment of DMF performed at 27 UK hospitals, adults were randomly allocated (1:1) to either usual standard of care alone or usual standard of care plus DMF. The primary outcome was clinical status on day 5 measured on a seven-point ordinal scale. Secondary outcomes were time to sustained improvement in clinical status, time to discharge, day 5 peripheral blood oxygenation, day 5 C-reactive protein, and improvement in day 10 clinical status. Between 2 March 2021 and 18 November 2021, 713 patients were enroled in the DMF evaluation, of whom 356 were randomly allocated to receive usual care plus DMF, and 357 to usual care alone. 95% of patients received corticosteroids as part of routine care. There was no evidence of a beneficial effect of DMF on clinical status at day 5 (common odds ratio of unfavourable outcome 1.12; 95% CI 0.86-1.47; p = 0.40). There was no significant effect of DMF on any secondary outcome

Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) inhibits inflammasome-mediated inflammation and has been proposed as a treatment for patients hospitalised with COVID-19. This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple treatments in patients hospitalised for COVID-19 (NCT04381936, ISRCTN50189673). In this assessment of DMF performed at 27 UK hospitals, adults were randomly allocated (1:1) to either usual standard of care alone or usual standard of care plus DMF. The primary outcome was clinical status on day 5 measured on a seven-point ordinal scale. Secondary outcomes were time to sustained improvement in clinical status, time to discharge, day 5 peripheral blood oxygenation, day 5 C-reactive protein, and improvement in day 10 clinical status. Between 2 March 2021 and 18 November 2021, 713 patients were enroled in the DMF evaluation, of whom 356 were randomly allocated to receive usual care plus DMF, and 357 to usual care alone. 95% of patients received corticosteroids as part of routine care. There was no evidence of a beneficial effect of DMF on clinical status at day 5 (common odds ratio of unfavourable outcome 1.12; 95% CI 0.86-1.47; p = 0.40). There was no significant effect of DMF on any secondary outcome

Habit-forming : reading Infinite jest as a rhetoric of humility

textIn this project, I argue that David Foster Wallace's 1996 novel Infinite jest (or IJ) is both about recovering from addiction through humility, and also it produces that humility in some of its readers by making us feel ourselves to be addicts to a certain kind of reading: a reading to find closure, certainty, and resolution. But, in frustrating the desires for closure, certainty, resolution, etc., IJ denies readers the satisfaction of completing the fix. It is precisely this denial that prompts readers to re-read, repeating the structure of addiction--but also destructuring it, by installing habits of reading that pleasure in the failure to close, the uncertainty, the impossibility of resolution--habits which I treat as humility. Following a thread in the performative theory of J.L. Austin, Jacques Derrida, and Eve Kosofsky Sedgwick, I clear space for reconceptualizing the performative utterance through an unusual example of a performative utterance: I take IJ to be the utterance of humility. Drawing on Avital Ronell's "narcoanalysis" in Crack wars, I argue that IJ's performative or substantializing work is in exploiting one kind of habit (addiction) in order to replace it with another (humility). The rhetorical transformation (to humility) effects itself through IJ's performative formation (in the reader) of the humbled habit. This project is a reading of a performative utterance (IJ) that produces a rhetorical effect, which effect is the formation of the habit of humility.Englis