Direct measurement of B(D_s^+ → φX^+)

The absolute inclusive branching fraction of D_s^+→φX^+ has been measured from data collected by the BES detector at a center-of-mass energy of 4.03 GeV, corresponding to an integrated luminosity of 22.3 pb^(-1). At this energy, direct pair production e^+e^-→D_s^+D_s^- has been observed. We have selected D_s candidate events by reconstructing five hadronic decay modes D_s^+→φπ^+, K^(0*)K^+, K^0K^+, f0^(π+) and K^0K^-π^+π^+ and have searched for inclusive φ’s in the recoiling D_s^-. We observed three recoiling φ’s in the 166.4 ± 31.8 D_s candidate events, which leads to the absolute branching fraction B(D_s^+→φX^+)=(17.8(-7.2 -6.3)^(+15.1+0.6)) % and B(D_s-6.3+→φπ-6.3+)=(3.6_(-1.6 -1.3)(^_3.1+0.4) %. [S0556-2821(97)02423-5

Measurement of the mass of the τ lepton

The mass of the τ lepton has been measured at the Beijing Electron-Positron Collider using the Beijing Spectrometer. A search near threshold for e^+e^-→τ^+τ^- was performed. Candidate events were identified by requiring that one τ decay via τ→eνν¯, and the other via τ→μνν¯. The mass value, obtained from a fit to the energy dependence of the τ^+τ^- cross section, is m_τ=1776.9_(-0.5)^(+0.4)±0.2 MeV

Characteristics and incidence of transfusion-associated necrotizing enterocolitis in the UK

BACKGROUND AND AIMS: The etiology of necrotizing enterocolitis (NEC) is unclear and postulated as being multifactorial. It has been suggested that one causative factor is the transfusion of packed red blood cells (PRBCs) leading to the disease entity commonly referred to as transfusion-associated NEC (TANEC). TANEC has been reported in North America but its incidence has not been formally investigated in the UK. Our aims were to identify the incidence of NEC and TANEC in tertiary-level UK neonatal units and to describe characteristics of TANEC cases. MATERIALS AND METHODS: Using strict case definitions for NEC and TANEC, we undertook a retrospective review to estimate the incidence of TANEC cases occurring in four UK tertiary-level centers during a 38-month period. RESULTS: Of 8007 consecutive neonatal admissions of all gestations to the four centers, 68 babies went on to develop NEC and all affected infants were of very low birth weight (VLBW); 34 of these had previously received a transfusion of PRBCs but did not fit the diagnostic criteria for TANEC, whereas 15 (22%) of the 68 babies with NEC qualified as TANEC cases. UK cases occurred at an earlier postnatal age than cases reported in multiple large North American series and were of a lower birth weight. CONCLUSIONS: We have confirmed the presence of TANEC in the UK VLBW neonatal population. Its incidence lies within the wide range described in previous reports of this phenomenon globally, though with some local variation in characteristics. Further work is needed to clarify causation, pathophysiology, and possible mechanisms of prevention of TANEC

Neuronal Glutamate Transporters Control Dopaminergic Signaling and Compulsive Behaviors

There is an ongoing debate on the contribution of the neuronal glutamate transporter EAAC1 to the onset of compulsive behaviors. Here, we used behavioral, electrophysiological, molecular, and viral approaches in male and female mice to identify the molecular and cellular mechanisms by which EAAC1 controls the execution of repeated motor behaviors. Our findings show that, in the striatum, a brain region implicated with movement execution, EAAC1 limits group I metabotropic glutamate receptor (mGluRI) activation, facilitates D1 dopamine receptor (D1R) expression, and ensures long-term synaptic plasticity. Blocking mGluRI in slices from mice lacking EAAC1 restores D1R expression and synaptic plasticity. Conversely, activation of intracellular signaling pathways coupled to mGluRI in D1R-containing striatal neurons of mice expressing EAAC1 leads to reduced D1R protein level and increased stereotyped movement execution. These findings identify new molecular mechanisms by which EAAC1 can shape glutamatergic and dopaminergic signals and control repeated movement execution

Effect of Financial Incentives to Physicians, Patients, or Both on Lipid Levels: A Randomized Clinical Trial

Can financial incentives be used to reduce cholesterol levels in high-risk patients? This randomized trial says modest reductions can be achieved only by targeting incentives to both patients and physicians, not to one or the other

Direct measurement of the D_s branching fraction to φπ

The Beijing Spectrometer (BES) Collaboration has observed exclusive pair production of D_s mesons at the Beijing Electron-Positron Collider (BEPC) at a center-of-mass energy of 4.03 GeV. The D_s mesons are detected in the φπ^+, K¯^(*0)K^+, and K¯^0K^+ decay modes; two fully reconstructed events yield the value (3.9_(-1.9-1.1)^(+5.1+1.8))% for the D_s branching fraction to φπ. This is the first direct, model-independent measurement of this quantity