Securing Water, Sustaining Growth: Report of the GWP/OECD Task Force on Water Security and Sustainable Growth

Peer Revie

Third party consultation: a method for the study and resolution of conflict

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66597/2/10.1177_002200277201600105.pd

Systematic Review of Medicine-Related Problems in Adult Patients with Atrial Fibrillation on Direct Oral Anticoagulants

New oral anticoagulant agents continue to emerge on the market and their safety requires assessment to provide evidence of their suitability for clinical use. There-fore, we searched standard databases to summarize the English language literature on medicine-related problems (MRPs) of direct oral anticoagulants DOACs (dabigtran, rivaroxban, apixban, and edoxban) in the treatment of adults with atri-al fibrillation. Electronic databases including Medline, Embase, International Pharmaceutical Abstract (IPA), Scopus, CINAHL, the Web of Science and Cochrane were searched from 2008 through 2016 for original articles. Studies pub-lished in English reporting MRPs of DOACs in adult patients with AF were in-cluded. Seventeen studies were identified using standardized protocols, and two reviewers serially abstracted data from each article. Most articles were inconclusive on major safety end points including major bleeding. Data on major safety end points were combined with efficacy. Most studies inconsistently reported adverse drug reactions and not adverse events or medication error, and no definitions were consistent across studies. Some harmful drug effects were not assessed in studies and may have been overlooked. Little evidence is provided on MRPs of DOACs in patients with AF and, therefore, further studies are needed to establish the safety of DOACs in real-life clinical practice

Dual Temperature Evaporator Refrigerator Design and Optimization

The primary focus of this thesis is on performance advantages of a dual-temperature evaporator refrigerator system over a conventional design. Through extensive use of computer-aided modeling, it is demonstrated that energy savings of at least 8-10% can be achieved if this design is coupled with variable speed compressor technology. In addition to the validation study, various optimization techniques that can be used to reduce energy consumption of sequential cooling systems are also introduced. These methods are subsequently applied to a particular experimental prototype design. The thesis also explores ways of reducing overall charge requirements for a refrigerator system by means of introducing parallel circuits in the heat exchangers. Other topics include evaporator de-superheating phenomenon, a series of studies on flow instabilities in capillary tubes, and a dual-speed compressor performance analysis. iAir Conditioning and Refrigeration Project 6

Geocode Matching and Privacy Preservation

Abstract. Geocoding is the process of matching addresses to geographic locations, such as latitudes and longitudes, or local census areas. In many applications, addresses are the key to geo-spatial data analysis and mining. Privacy and confidentiality are of paramount importance when data from, for example, cancer registries or crime databases is geocoded. Various approaches to privacy-preserving data matching, also called record linkage or entity resolution, have been developed in recent times. However, most of these approaches have not considered the specific privacy issues involved in geocode matching. This paper provides a brief introduction to privacy-preserving data and geocode matching, and using several real-world scenarios the issues involved in privacy and confidentiality for data and geocode matching are illustrated. The challenges of making privacy-preserving matching practical for real-world applications are highlighted, and potential directions for future research are discussed