6,645 research outputs found
Seasonal Price Patterns for Arkansas Soybeans
Seasonality is generally regarded as a major feature in soybean market price variations. Recent years in Arkansas have seen considerable construction of on-farm storage, a move that could mitigate the seasonality effect on price variations. A study comparing cash price indices from the past ten years with results from a 1986 Arkansas study and a recent national-level study found that Arkansas soybean prices appear to have followed a consistent and logical pattern around their national average in spite of increased variability and uncertainty.Seasonality, soybean, cash price index, Demand and Price Analysis, Farm Management, Marketing,
Assessment of synchrony in multiple neural spike trains using loglinear point process models
Neural spike trains, which are sequences of very brief jumps in voltage
across the cell membrane, were one of the motivating applications for the
development of point process methodology. Early work required the assumption of
stationarity, but contemporary experiments often use time-varying stimuli and
produce time-varying neural responses. More recently, many statistical methods
have been developed for nonstationary neural point process data. There has also
been much interest in identifying synchrony, meaning events across two or more
neurons that are nearly simultaneous at the time scale of the recordings. A
natural statistical approach is to discretize time, using short time bins, and
to introduce loglinear models for dependency among neurons, but previous use of
loglinear modeling technology has assumed stationarity. We introduce a succinct
yet powerful class of time-varying loglinear models by (a) allowing
individual-neuron effects (main effects) to involve time-varying intensities;
(b) also allowing the individual-neuron effects to involve autocovariation
effects (history effects) due to past spiking, (c) assuming excess synchrony
effects (interaction effects) do not depend on history, and (d) assuming all
effects vary smoothly across time.Comment: Published in at http://dx.doi.org/10.1214/10-AOAS429 the Annals of
Applied Statistics (http://www.imstat.org/aoas/) by the Institute of
Mathematical Statistics (http://www.imstat.org
Passive wireless tags for tongue controlled assistive technology interfaces
Tongue control with low profile, passive mouth tags is demonstrated as a human–device interface by communicating values of tongue-tag
separation over a wireless link. Confusion matrices are provided to demonstrate user accuracy in targeting by tongue position. Accuracy is
found to increase dramatically after short training sequences with errors falling close to 1% in magnitude with zero missed targets. The
rate at which users are able to learn accurate targeting with high accuracy indicates that this is an intuitive device to operate. The
significance of the work is that innovative very unobtrusive, wireless tags can be used to provide intuitive human–computer interfaces
based on low cost and disposable mouth mounted technology. With the development of an appropriate reading system, control of assistive
devices such as computer mice or wheelchairs could be possible for tetraplegics and others who retain fine motor control capability of
their tongues. The tags contain no battery and are intended to fit directly on the hard palate, detecting tongue position in the mouth with
no need for tongue piercings
Quantification of Pulmonary Arterial Wall Distensibility Using Parameters Extracted from Volumetric Micro-CT Images
Stiffening, or loss of distensibility, of arterial vessel walls is among the manifestations of a number of vascular diseases including pulmonary arterial hypertension. We are attempting to quantify the mechanical properties of vessel walls of the pulmonary arterial tree using parameters derived from high-resolution volumetric x-ray CT images of rat lungs. The pulmonary arterial trees of the excised lungs are filled with a contrast agent. The lungs are imaged with arterial pressures spanning the physiological range. Vessel segment diameters are measured from the inlet to the periphery, and distensibilities calculated from diameters as a function of pressure. The method shows promise as an adjunct to other morphometric techniques such as histology and corrosion casting. It possesses the advantages of being nondestructive, characterizing the vascular structures while the lungs are imaged rapidly and in a near-physiological state, and providing the ability to associate mechanical properties with vessel location in the intact tree hierarchy
Distance Learning In Hybrid Courses In A Us/France MBA Program: Two Years Of Experience.
Online instruction has become part of many academic programs. With online instruction students can be located away from the physical classroom, a mode called distance learning. Sometimes online/distance instruction is coupled with face-to-face instruction in a hybrid or blended learning approach. San Francisco State University and the University of Nice-Sophia Antipolis use a hybrid approach to conduct several courses in their joint MBA program taught in Nice, France, and San Francisco, California. This paper looks at the first two years of experience in this program to examine faculty and student perceptions of the effectiveness of the distance delivery parts of the courses using different online tools. A survey of faculty and students who participated in the hybrid learning courses in the program was conducted, and the results are reported in the paper. The paper concludes that synchronous online tools were generally effective but asynchronous online tools were not
False discovery rate regression: an application to neural synchrony detection in primary visual cortex
Many approaches for multiple testing begin with the assumption that all tests
in a given study should be combined into a global false-discovery-rate
analysis. But this may be inappropriate for many of today's large-scale
screening problems, where auxiliary information about each test is often
available, and where a combined analysis can lead to poorly calibrated error
rates within different subsets of the experiment. To address this issue, we
introduce an approach called false-discovery-rate regression that directly uses
this auxiliary information to inform the outcome of each test. The method can
be motivated by a two-groups model in which covariates are allowed to influence
the local false discovery rate, or equivalently, the posterior probability that
a given observation is a signal. This poses many subtle issues at the interface
between inference and computation, and we investigate several variations of the
overall approach. Simulation evidence suggests that: (1) when covariate effects
are present, FDR regression improves power for a fixed false-discovery rate;
and (2) when covariate effects are absent, the method is robust, in the sense
that it does not lead to inflated error rates. We apply the method to neural
recordings from primary visual cortex. The goal is to detect pairs of neurons
that exhibit fine-time-scale interactions, in the sense that they fire together
more often than expected due to chance. Our method detects roughly 50% more
synchronous pairs versus a standard FDR-controlling analysis. The companion R
package FDRreg implements all methods described in the paper
Pulmonary arterial remodeling revealed by microfocal x-ray tomography
Animal models and micro-CT imaging are useful for understanding the functional consequences of, and identifying the genes involved in, the remodeling of vascular structures that accompanies pulmonary vascular disease. Using a micro-CT scanner to image contrast-enhanced arteries in excised lungs from fawn hooded rats (a strain genetically susceptible to hypoxia induced pulmonary hypertension), we found that portions of the pulmonary arterial tree downstream from a given diameter were morphometrically indistinguishable. This \u27self-consistency\u27 property provided a means for summarizing the pulmonary arterial tree architecture and mechanical properties using a parameter vector obtained from measurements of the contiguous set of vessel segments comprising the longest (principal) pathway and its branches over a range of vascular pressures. This parameter vector was used to characterize the pulmonary vascular remodeling that occurred in rats exposed to a hypoxic (11.5% oxygen) environment and provided the input to a hemodynamic model relating structure to function. The major effect of the remodeling was a longitudinally (pulmonary artery to arterioles) uniform decrease in vessel distensibility that resulted in a 90% increase in arterial resistance. Despite the almost uniform change in vessel distensibility, over 50% of the resistance increase was attributable to vessels with unstressed diameters less than 125 microns
Micro-CT Image-Derived Metrics Quantify Arterial Wall Distensibility Reduction in a Rat Model of Pulmonary Hypertension
We developed methods to quantify arterial structural and mechanical properties in excised rat lungs and applied them to investigate the distensibility decrease accompanying chronic hypoxia-induced pulmonary hypertension. Lungs of control and hypertensive (three weeks 11% O2) animals were excised and a contrast agent introduced before micro-CT imaging with a special purpose scanner. For each lung, four 3D image data sets were obtained, each at a different intra-arterial contrast agent pressure. Vessel segment diameters and lengths were measured at all levels in the arterial tree hierarchy, and these data used to generate features sensitive to distensibility changes. Results indicate that measurements obtained from 3D micro-CT images can be used to quantify vessel biomechanical properties in this rat model of pulmonary hypertension and that distensibility is reduced by exposure to chronic hypoxia. Mechanical properties can be assessed in a localized fashion and quantified in a spatially-resolved way or as a single parameter describing the tree as a whole. Micro-CT is a nondestructive way to rapidly assess structural and mechanical properties of arteries in small animal organs maintained in a physiological state. Quantitative features measured by this method may provide valuable insights into the mechanisms causing the elevated pressures in pulmonary hypertension of differing etiologies and should become increasingly valuable tools in the study of complex phenotypes in small-animal models of important diseases such as hypertension
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