3,134 research outputs found

    A comparison of surface sensible and latent heat fluxes from aircraft and surface measurements in FIFE 1987

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    Surface fluxes of sensible and latent heat over a tall-grass prairie in central Kansas, as measured by 22 surface stations during FIFE 1987, are compared with values gained indirectly by linear extrapolation of aircraft-measured flux profiles to the surface. The results of 33 such comparisons covering the period 26 June to 13 October 1987 indicate that the sensible heat flux profiles were generally more linear with less scatter in the measurements at each level than were the latent heat flux profiles, the profile extrapolations of sensible heat flux in general underestimate the surface averages by about 30 percent, with slightly better agreement during periods of small flux, and the profile extrapolations of latent heat flux in general underestimate the surface averages by about 15 percent, with overestimates during periods of small fluxes (dry conditions) and overestimates during periods of large fluxes (moist conditions). Possible origins of the differences between the two sets of measurements are discussed, as directions for further research

    Individual differences in striatum activity to food commercials predict weight gain in adolescents

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109559/1/oby20882.pd

    Experimental strategies for the study of cellular immunity in renal disease

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    Managing Interspecies Competition to Improve Spring Pasture

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    Orchardgrass (Dactylis glomerata L.) is one of the earliest maturing pasture grasses utilized in the northeastern United States. However, wet springs can delay forage harvesting resulting in advanced forage maturity and reduction in nutritive value. Chicory (Cichorium intybus L.) is a tall, upright-growing forb that shows promise as a high-energy companion crop to orchardgrass and may delay orchardgrass maturity through shading effects on plant morphology. The objective of this study was to evaluate monocultures and mixtures of orchardgrass, chicory, and white clover (Trifolium repens L.) over two consecutive springs to determine the effects of species diversity on plant maturity, nutritive characteristics, and botanical composition of forage mass. Forage monocultures and mixtures were planted in central Pennsylvania in August 2018 and were observed for two years with three harvests occurring each year (one each in spring, summer, and fall). In the first spring, orchardgrass demonstrated nine days delay in maturity when grown with chicory as compared to when grown in monocultures or in orchardgrass-white clover mixtures. Although orchardgrass was at an earlier developmental stage, fiber concentrations were similar when grown with or without chicory. Additionally, in the first spring, orchardgrass mixtures containing chicory had 1.5x greater forage mass than orchardgrass monocultures and orchardgrass-white clover mixtures. Chicory biomass was low in the second spring, likely due to winterkill following a late fall harvest the previous year, resulting in a negligible effect on orchardgrass. However, orchardgrass-chicory-white clover mixtures (even with low amounts of chicory in the second year) had the greatest forage mass and nutritive value yield over both years, indicating that these mixtures can provide greater agronomic benefits than orchardgrass monocultures

    Factors Associated with Persistence with Teriparatide Therapy: Results from the DANCE Observational Study

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    Purpose. Determine patient-reported reasons for discontinuation with teriparatide. Methods. Patients taking teriparatide in a multicenter, prospective, and observational study were given three questionnaires: baseline, follow-up questionnaire 1 (QF1, 2 to 6 months), and follow-up questionnaire 2 (QF2, 12 months). Discontinuation reported at QF1 and QF2 was defined as “early” and “late,” respectively, and remaining patients were considered persistent. Cochran-Armitage trend test was used to identify factors associated with discontinuation. Results. Side effects, concern about improper use, injection difficulties, and several patient-perceived physician issues were associated with early discontinuation. Low patient-perceived importance of continuing treatment, side effects, difficulty paying, and low patient-perceived physician knowledge were associated with late discontinuation. The most common specific reasons selected for discontinuing treatment were “concerns about treatment outweighing the benefits” (n = 53) and “difficulty paying” (n = 47). Conclusions. Persistence with teriparatide is dependent on managing side effects, addressing financial challenges, proper training, and obtaining support from the healthcare provider

    Northern Bobwhite Response to Control of Red Imported Fire Ants in the Gulf Coast Prairie of Texas

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    The population decline of northern bobwhite (Colinus virginianus; hereafter, bobwhite) on the Texas Gulf Coast Prairie, USA is largely attributed to habitat loss. However, red imported fire ants (Solenopsis invicta) occur throughout the region and are considered a possible contributing factor to the bobwhite decline. The objectives of our study were to determine the influence of red imported fire ants on bobwhites by comparing bobwhite nest success, survival, and density between sites treated with fire ant bait (treatment) and reference (control) sites. Our study was conducted on 3 private ranches in Goliad and Refugio counties, Texas. Each ranch contained 2 paired experimental units that consisted of a treatment and control site (500 ha each). The treatment sites received an aerial application of fire ant bait (Extinguish® Plus) during April 2018, whereas the control sites were not treated. We estimated mound density by counting fire ant mounds using distance sampling. We used radio-telemetry to monitor bobwhite nest success and survival, and we estimated bobwhite densities using distance sampling via helicopter surveys. Fire ant mound density decreased through time on both treatment and control sites. However, fire ant mound density was lower on treatment sites than control sites, indicating the insecticide was effective at decreasing fire ant mound density. Bobwhite survival, nest success, and density did not statistically differ between control and treated sites either pre-treatment (2017) or post-treatment (2018), but survival and nest success metrics were numerically higher in treated units. Bobwhite survival remained relatively stable in the treatment units 4 weeks after application but decreased in the control units. Following treatment, apparent nest success in the treated units increased by 37.4% while nest success in the control units decreased by 35.2%. Bobwhite populations were low in this ecoregion, which influenced our ability to trap and monitor many bobwhites or monitor many nests. In addition, it may be possible that repeated, annual treatments for fire ants are necessary for a benefit to accrue and be observed in bobwhites. Our results indicate that there may be potential benefits to bobwhites from fire ant reduction that deserve further research attention

    Experimental analysis of the effect of taxes and subsides on calories purchased in an on-line supermarket

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    Taxes and subsidies are a public health approach to improving nutrient quality of food purchases. While taxes or subsidies influence purchasing, it is unclear whether they influence total energy or overall diet quality of foods purchased. Using a within subjects design, selected low nutrient dense foods (e.g. sweetened beverages, candy, salty snacks) were taxed, and fruits and vegetables and bottled water were subsidized by 12.5% or 25% in comparison to a usual price condition for 199 female shoppers in an experimental store. Results showed taxes reduced calories purchased of taxed foods (coefficient = -6.61, Cl = -11.94 to -1.28) and subsidies increased calories purchased of subsidized foods (coefficient = 13.74, Cl = 8.51 to 18.97). However, no overall effect was observed on total calories purchased. Both taxes and subsidies were associated with a reduction in calories purchased for grains (taxes: coefficient = -6.58, Cl = -11.91 to -1.24, subsidies: coefficient = -12.86, Cl = -18.08 to -7.63) and subsidies were associated with a reduction in calories purchased for miscellaneous foods (coefficient = -7.40, CI = -12.62 to -2.17) (mostly fats, oils and sugars). Subsidies improved the nutrient quality of foods purchased (coefficient = 0.14, Cl = 0.07 to 0.21). These results suggest that taxes and subsidies can influence energy purchased for products taxed or subsidized, but not total energy purchased. However, the improvement in nutrient quality with subsidies indicates that pricing can shift nutritional quality of foods purchased. Research is needed to evaluate if differential pricing strategies based on nutrient quality are associated with reduction in calories and improvement in nutrient quality of foods purchased

    Temporal and spatial changes in cartilage-matrix-specific gene expression in mesenchymal stem cells in response to dynamic compression.

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    Various forms of mechanical stimulation have been shown to enhance chondrogenesis of mesenchymal stem cells (MSCs). However, the response of MSCs undergoing chondrogenesis to such signals has been shown to depend on the temporal application of loading. The objective of this study was to determine the effect of dynamic compression on cartilage-matrix-specific gene expression and to relate this response to the local biochemical environment and cell phenotype at the time of loading. At 0, 7, 14, and 21 days extracellular matrix (ECM) deposition within MSC-seeded agarose hydrogels due to transforming growth factor-β3 stimulation was determined biochemically and histologically, and then reverse transcription-polymerase chain reaction was used to examine the effects of dynamic compression on cartilage-matrix-specific gene expression. The results of these experiments show that the local environment in the core of the constructs is more favorable for chondrogenesis in comparison to the annulus, as evident from both ECM synthesis and gene expression. Additionally, we found that the response of the cells to mechanical stimulus varied with both the spatial region within the constructs and the temporal application of loading. Dynamic compression applied at day 21 was found to enhance levels of cartilage matrix gene expression following a peak in expression levels at day 14 in free swelling constructs, suggesting that mechanical signals play a key role in the maintenance of a chondrogenic phenotype. The application of mechanical stimulus to enhance cartilage ECM synthesis may be an important tool in regenerative medicine-based cartilage repair. The results of this study suggest that a chondrogenic phenotype and/or a well-developed pericellular matrix must first be established before dynamic compression can have a positive effect on cartilage-matrix-specific gene expression
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