1,243 research outputs found

    A Systems Theory Perspective

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    Aktualisierung: Am 12. Oktober 2018 wurde die digitale Version des Buchbeitrags um den fehlenden Teil (Seiten 53-66) ergÀnzt

    A time-lapse imaging platform for quantification of soil crack development due to simulated root water uptake

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    Plants are major drivers of soil structure dynamics. Root growth creates new macropores and provides essential carbon to soil, while root water uptake may induce crack formation around roots. Cracks can facilitate root growth as they provide pathways of least resistance and improve water infiltration and soil aeration. Due to the lack of suitable quantification methods, knowledge on the effects of root water uptake on soil crack formation remains limited. In the current study, we developed a time-lapse imaging platform that allows i) simulating root water uptake through localized soil drying and ii) quantifying the development of two-dimensional crack networks. Customized soil boxes that were 50 mm wide, 55 mm high and 5 mm deep were designed. Artificial roots made of dialysis tubes were inserted into the soil boxes and polyethylene glycol solution was circulated through the tubes. This induced a gradient in osmotic potential at the contact area (150 mm(2)) between the soil and the dialysis tubes, resulting in controlled soil drying. Drying intensity was varied by using different polyethylene glycol concentrations. Experiments were conducted with three soils that were subjected to three drying intensities for 6.5 days. We developed a time-lapse imaging system to record soil crack formation at two-minute intervals in twelve samples simultaneously. Resulting crack networks were quantified with an automated image analysis pipeline. Across soils and drying intensities, crack network development slowed down after 24-48 h of soil drying. The extent and complexity of crack networks increased with drying intensity and crack networks were larger and more complex in the clay and clay loam soil than in the silt loam soil. Smaller and less complex crack networks were better connected than larger and more complex networks. These results demonstrate that the platform developed in this study is suitable to quantify crack network development in soil due to simulated root water uptake at high temporal resolution and high throughput. Thereby, it can provide information needed to improve our understanding on how plants modify soil structure

    Decision making preferences in the medical encounter – a factorial survey design

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    <p>Abstract</p> <p>Background</p> <p>Up to now it has not been systematically investigated in which kind of clinical situations a consultation style based on shared decision making (SDM) is preferred by patients and physicians. We suggest the factorial survey design to address this problem.</p> <p>This method, which so far has hardly been used in health service research, allows to vary relevant factors describing clinical situations as variables systematically in an experimental random design and to investigate their importance in large samples.</p> <p>Methods/Design</p> <p>To identify situational factors for the survey we first performed a literature search which was followed by a qualitative interview study with patients, physicians and health care experts. As a result, 7 factors (e.g. "Reason for consultation" and "Number of therapeutic options") with 2 to 3 levels (e.g. "One therapeutic option" and "More than one therapeutic option") will be included in the study. For the survey the factor levels will be randomly combined to short stories describing different treatment situations.</p> <p>A randomized sample of all possible short stories will be given to at least 300 subjects (100 GPs, 100 patients and 100 members of self-help groups) who will be asked to rate how the decision should be made. Main outcome measure is the preference for participation in the decision making process in the given clinical situation.</p> <p>Data analysis will estimate the effects of the factors on the rating and also examine differences between groups.</p> <p>Discussion</p> <p>The results will reveal the effects of situational variations on participation preferences. Thus, our findings will contribute to the understanding of normative values in the medical decision making process and will improve future implementation of SDM and decision aids.</p

    Adding insult to injury:Illegitimate stressors and their association with situational well-being, social self-esteem, and desire for revenge

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    Implying an offense to self, appraising a stressor as indicating a lack of consideration by others should have effects beyond its stressfulness per se. In Stress-as-Offense-to-Self theory (SOS), such stressors are called “illegitimate stressors.” We assessed situations appraised as stressful in two diary studies (N 1 = 117, N 2 = 137). Outcome variables were feelings of resentment in both studies, plus nervousness, anxiety, and sadness in Study 1 and depressive mood, threat to social self-esteem, and desire for revenge in Study 2. Controlling for stressfulness, perceived illegitimacy predicted affective reactions that are outward-directed (feelings of resentment [Studies 1 and 2], threat to social self-esteem and desire for revenge [Study 2]); it also predicted sadness in Study 1 but not depressive mood in Study 2, nor nervousness (Study 1). Thus, not all hypotheses were confirmed but the pattern was as expected, in that results were consistent regarding outcomes typically associated with the attribution of blame. The independent contribution of perceived illegitimacy aligns well with the underlying Stress-as-Offense-to-Self theory. Practical implications refer to efforts to avoid illegitimate stressors, for instance by perspective-taking, by showing appreciation and support, and by supporting such behaviours through keeping stressors in general at a manageable level

    Pitfalls in the statistical examination and interpretation of the correspondence between physician and patient satisfaction ratings and their relevance for shared decision making research

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    BACKGROUND: The correspondence of satisfaction ratings between physicians and patients can be assessed on different dimensions. One may examine whether they differ between the two groups or focus on measures of association or agreement. The aim of our study was to evaluate methodological difficulties in calculating the correspondence between patient and physician satisfaction ratings and to show the relevance for shared decision making research. METHODS: We utilised a structured tool for cardiovascular prevention (arribaℱ) in a pragmatic cluster-randomised controlled trial. Correspondence between patient and physician satisfaction ratings after individual primary care consultations was assessed using the Patient Participation Scale (PPS). We used the Wilcoxon signed-rank test, the marginal homogeneity test, Kendall's tau-b, weighted kappa, percentage of agreement, and the Bland-Altman method to measure differences, associations, and agreement between physicians and patients. RESULTS: Statistical measures signal large differences between patient and physician satisfaction ratings with more favourable ratings provided by patients and a low correspondence regardless of group allocation. Closer examination of the raw data revealed a high ceiling effect of satisfaction ratings and only slight disagreement regarding the distributions of differences between physicians' and patients' ratings. CONCLUSIONS: Traditional statistical measures of association and agreement are not able to capture a clinically relevant appreciation of the physician-patient relationship by both parties in skewed satisfaction ratings. Only the Bland-Altman method for assessing agreement augmented by bar charts of differences was able to indicate this

    StOP? II trial: cluster randomized clinical trial to test the implementation of a toolbox for structured communication in the operating room-study protocol.

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    BACKGROUND Surgical care, which is performed by intensely interacting multidisciplinary teams of surgeons, anesthetists, and nurses, remains associated with significant morbidity and mortality. Intraoperative communication has been shown to be associated with surgical outcomes, but tools ensuring efficient intraoperative communication are lacking. In a previous study, we developed the StOP?-protocol that fosters structured intraoperative communication. Before the critical phases of the operation, the responsible surgeon initiates and leads one or several StOP?s. During a StOP?, the surgeon informs about the progress of the operation (status), next steps and proximal goals (objectives), and possible problems (problems) and encourages all team members to voice their observations and ask questions (?). In a before-after study performed mainly in visceral surgery, we found effects of the StOP?-protocol on mortality, length of hospital stay, and reoperation. We intend to assess the impact of the StOP?-protocol in a cluster randomized trial, in a wider variety of surgical specialties (i.e., general, visceral, thoracic, vascular surgery, surgical urology, and gynecology). The primary hypothesis is that the consistent use of the StOP?-protocol by the main surgeon reduces patient mortality within 30 days after the operation. The secondary hypothesis is that the consistent use of the StOP?-protocol by the main surgeon reduces unplanned reoperations, length of hospital stay, and unplanned hospital readmissions. METHODS This study is designed as a multicenter, cluster-randomized parallel-group trial. Board-certified surgeons of participating clinical departments will be randomized 1:1 to the StOP? intervention group or to the standard of care (control) group. The intervention group will undergo a training to use the StOP?-protocol and receive regular feedback on their compliance with the protocol. The surgeons in the control group will communicate as usual during their operations. The unit of observation will be operations performed by cluster surgeons. Consecutive patients will be enrolled over 4 months per cluster. A total of 400 surgeons will be recruited, and we expect to collect patient outcome data for 14,000 surgical procedures. DISCUSSION The StOP?-protocol was designed as a tool to structure communication during surgical procedures. Testing its effects on patient outcomes will contribute to implementing evidenced-based interventions to reduce surgical complications. TRIAL REGISTRATION ClinicalTrials.gov NCT05356962. Registered on May 2, 2022

    A universal smartphone add-on for portable spectroscopy and polarimetry: iSPEX 2

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    Spectropolarimetry is a powerful technique for remote sensing of the environment. It enables the retrieval of particle shape and size distributions in air and water to an extent that traditional spectroscopy cannot. SPEX is an instrument concept for spectropolarimetry through spectral modulation, providing snapshot, and hence accurate, hyperspectral intensity and degree and angle of linear polarization. Successful SPEX instruments have included groundSPEX and SPEX airborne, which both measure aerosol optical thickness with high precision, and soon SPEXone, which will fly on PACE. Here, we present a low-cost variant for consumer cameras, iSPEX 2, with universal smartphone support. Smartphones enable citizen science measurements which are significantly more scaleable, in space and time, than professional instruments. Universal smartphone support is achieved through a modular hardware design and SPECTACLE data processing. iSPEX 2 will be manufactured through injection molding and 3D printing. A smartphone app for data acquisition and processing is in active development. Production, calibration, and validation will commence in the summer of 2020. Scientific applications will include citizen science measurements of aerosol optical thickness and surface water reflectance, as well as low-cost laboratory and portable spectroscopy.Comment: 16 pages, 11 figures, SPIE Defense + Commercial Sensing 202

    Randomized Controlled Clinical Trial of Blood Glucose Awareness Training (BGAT III) in Switzerland and Germany

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    Although both diabetes and the efficacy of medical management are international issues, psycho-educational interventions might be culturally bound. Blood Glucose Awareness Training (BGAT) is a psycho-educational program for patients with type 1 diabetes mellitus. It is focused on improving recognition and management of extreme blood glucose levels, and is the best documented American psycho-educational program for this purpose. A randomized controlled clinical trial of BGAT's long-term benefits in a non-American setting has been lacking. One hundred and eleven adults with type 1 diabetes mellitus from Switzerland and Germany participated. After a 6 months baseline assessment, subjects were randomly assigned to receive either 2 months of BGAT (n = 56) or a physician-guided self-help control intervention (n = 55). BGAT improved recognition of low (p = 0.008), high (p = .03), and overall blood glucose (p = 0.001), and reduced frequency of severe hypoglycemia (p = 0.04), without compromising metabolic control. BGAT reduced both the external locus of control (p < 0.02) and fear of hypoglycemia (p < 0.02). BGAT was efficacious in reducing adverse clinical events and achieving clinically desirable goals in a European, as well as American settin
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