Data on the clinical aspects and therapy of primary gastrointestinal lymphomas

Fifteen cases of primary gastrointestinal lymphoma diagnosed over 8 years are reviewed. In the period 1980 to 1982 there was a cumulative appearance of GI lymphomas, nine out of 15 cases were diagnosed in that period. According to its localization, lymphoma occurred in 12 cases in the stomach, and in 3 in the small intestines and the colon. One case of gastric lymphoma was Hodgkin type, the others were non-Hodgkin types. The clinical symptoms were not characteristic of lymphoma. The age of the patients was, on the average, ten years lower than the mean age of carcinoma patients. Preoperative diagnosis by gastric biopsy was successful in four cases. In patients with lymphoma of the colon not subjects to surgery, colonoscopy verified the origin of lymphoma. Exact clinical classification in the majority of cases was made intraoperatively. In the non-operated cases, sonography and lymphography were performed. In general, operation was attempted, but patients in stage II, in very poor condition, were possibly not operated. The possibility and indications of the "second look" operation are discussed. Histological typing was made according to the Kiel classification. In the literature, in the most controversial question of therapy, individual consideration of the cases is recommended. Based on our experience, in devising therapy or therapeutic strategy as well as concerning prognosis, the degree of malignancy according to histological type, clinical stage and anatomical localization seem to be the most decisive factors. In exceptionally malignant cases a protocol with doxorubicine + bleomycin + teniposide and prednisolone was applied

Model driven development approaches for mobile applications: A survey

The usage and development of mobile applications (referred to as apps) are experiencing exponential growth. Moreover, the vastness and diversity of mobile devices and operating systems oblige the software companies, that want to reach a wide audience, to develop and deploy the same app several times, once for each targeted platforms. Furthermore, the dilemma between browser-based and native user interfaces remains relevant and challenges the capacity of organizations to meet the increasing demand for mobile apps. The adoption of model driven development (MDD) can simplify the development of mobile apps, reducing significantly technical complexity and development costs. Several researches have applied MDD techniques to address these challenges. In this paper, we define a set of criteria to assess the current model driven approaches to mobile apps development. We classify those approaches according the defined classification schema and present the current trends and challenges in this field. The survey shows a preference of code generation over model interpretation and of native apps over cross-platform ones