The High Time Resolution Universe surveys for pulsars and fast transients

The High Time Resolution Universe survey for pulsars and transients is the first truly all-sky pulsar survey, taking place at the Parkes Radio Telescope in Australia and the Effelsberg Radio Telescope in Germany. Utilising multibeam receivers with custom built all-digital recorders the survey targets the fastest millisecond pulsars and radio transients on timescales of 64 us to a few seconds. The new multibeam digital filter-bank system at has a factor of eight improvement in frequency resolution over previous Parkes multibeam surveys, allowing us to probe further into the Galactic plane for short duration signals. The survey is split into low, mid and high Galactic latitude regions. The mid-latitude portion of the southern hemisphere survey is now completed, discovering 107 previously unknown pulsars, including 26 millisecond pulsars. To date, the total number of discoveries in the combined survey is 135 and 29 MSPs. These discoveries include the first magnetar to be discovered by it's radio emission, unusual low-mass binaries, gamma-ray pulsars and pulsars suitable for pulsar timing array experiments.Comment: Proceedings of IAUS 291 "Neutron Stars and Pulsars: Challenges and Opportunities after 80 years"; J. van Leeuwen (ed.); 6 pages, 2 figure

Integrating management tools and concepts to develop an estuarine planning support system: A case study of the Humber Estuary, Eastern England

© 2015. Estuaries are important because of their multiple uses and users which often makes them challenging to manage since management must strike a balance between the needs of users, the estuaries' ecological and economic value and the context of multiple legislative drivers. To facilitate management we have therefore developed an Estuarine Planning Support System (EPSS) framework using the Humber Estuary, Eastern England, as a case study which integrates the current legislation tools and concepts. This integrated EPSS framework is an improvement on previous approaches for assessing cumulative impacts as it takes into account legislative drivers, management tools and other mechanisms for controlling plans/projects specific to the estuary. It therefore enables managers and users to assess and address both the current state and the way in which a new industrial, port or urban development could impact an estuary in an accessible and understandable framework

The Effect of Propranolol and Midazolam on the Reconsolidation of a Morphine Place Preference in Chronically Treated Rats

A stable memory can be disrupted if amnestic treatment is applied in conjunction with memory reactivation. Recent findings in the conditioned place preference (CPP) model suggest that blocking reconsolidation attenuates the ability of environmental cues to induce craving and relapse in drug addicts, but the impact of prior physical dependence has not been described. We examined the effect of post-reactivation amnestic treatment on reconsolidation of a CPP for morphine, in animals naïve to morphine, under chronic morphine experience or abstinent. Chronic morphine experience was induced by escalating doses of morphine from 10 mg/kg/day (s.c.), and maintained on 30 mg/kg/day during the course of conditioning and reactivation procedures, or conditioning alone. Naïve and morphine-experienced animals were trained in a three-compartment apparatus by four morphine (5 mg/kg, s.c.) and four saline experiences paired with either of two large conditioning compartments. The memory was then reactivated by a CPP test, and immediately afterward animals received an injection of the beta-adrenergic antagonist propranolol (10 mg/kg, s.c.), the GABAa agonist midazolam (1 mg/kg, i.p.), or saline. Morphine-naïve rats received only a single reconsolidation-blocking treatment (Experiment 1), while chronic morphine rats were given eight reactivation sessions each followed by amnestic treatment, either before (Experiment 2) or after 10 days of withdrawal (Experiment 3). Propranolol and midazolam disrupted reconsolidation in morphine-naïve rats, but failed to disrupt the CPP when rats were trained under chronic morphine treatment, even if they were recovered from chronic opiate exposure before reactivation. In fact, propranolol increased the preference for the drug-paired context in animals trained while maintained on chronic morphine. Midazolam had little effect. Morphine experience may produce neurochemical changes which alter memory storage processes and reduce the impact of amnestic treatments on reconsolidation

Impact of quasi-periodic and steep-spectrum timing noise on the measurement of pulsar timing parameters

Timing noise in pulsars is often modelled with a Fourier-basis Gaussian process that follows a power law with periodic boundary conditions on the observation time, $T_\mathrm{span}$. However the actual noise processes can extend well below $1/T_\mathrm{span}$, and many pulsars are known to exhibit quasi-periodic timing noise. In this paper we investigate several adaptions that try to account for these differences between the observed behaviour and the simple power-law model. Firstly, we propose to include an additional term that models the quasi-periodic spin-down variations known to be present in many pulsars. Secondly, we show that a Fourier basis of $1/2T_\mathrm{span}$ can be more suited for estimating long term timing parameters such as the spin frequency second derivative (F2), and is required when the exponent of the power spectrum is greater than ~4. We also implement a Bayesian version of the generalised least squares `Cholesky' method which has different limitations at low frequency, but find that there is little advantage over Fourier-basis methods. We apply our quasi-periodic spin down model to a sample of pulsars with known spin-down variations and show that this improves parameter estimation of F2 and proper motion for the most pathological cases, but in general the results are consistent with a power-law model. The models are all made available through the run_enterprise software package.Comment: This article has been accepted for publication in MNRAS Published by Oxford University Press on behalf of the Royal Astronomical Societ