Additional file 1: Figure S1. of Characterization of an epimastigote-stage-specific hemoglobin receptor of Trypanosoma congolense

The Southern blot analysis of the TcHpHbR gene. TcIL3000 genomic DNA treated with NsiI (lane 1), SacII (lane 2), PstI (lane 3) or neat TcIL3000 genomic DNA (lane 4) was subjected to Southern blotting. (PPTX 1.18 mb

Additional file 3: Figure S1. of Isolation, cultivation and molecular characterization of a new Trypanosoma equiperdum strain in Mongolia

The phylogenetic tree of the 18S rRNA and ITS region. A phylogenetic analysis was performed using the T. equiperdum IVM-t1, SITB818, STIB841, STIB842, BoTat1.1, T. evansi Tansui (Accession No. D89527.1), Cairo (AB551922.1), KAI.2 (AY912277), Sam.2 (AY912279.1), T. brucei TREU927 (AC012647), T. b. gambiense DAL972 (FN554966.1), T. b. gambiense Tsuua (AJ009141) and T. b. rhodesiense Utro (AJ009142) sequences. A: A phylogenetic tree based on the 18S rRNA sequence. B: A phylogenetic tree based on the ITS sequence. Figure S2. The maxicircle PCR of the Trypanozoon species. Gel electrophoresis images of the PCR products are shown in A to G, NADH-dehydrogenase subunit 7 (NAD7; 383 bp), Cytochrome oxidase subunit 2 (Cox2; 1747 bp), ATOas subunit 6 (A6; 299 bp), 12S ribosomal RNA (12S rRNA; 1597 bp in T. b. brucei GUTat3.1 strain and T. equiperdum STIB818 strain, 1415 bp in T. equiperdum STIB841, STIB842, BoTat1.1 strains, respectively), NADH-dehydrogenase subunit 7-cytochromeB (ND7-CyB; 1450 bp), Maxicircle unknown reading frame-NADH dehydrogenase subunit 1 (MURF-ND1; 1779 bp) and Maxicircle unknown reading frame 2-cytochrome oxidase subunit 1 (MURF2-Cox1; 1551 bp), respectively. M: the 100 bp and 1 kbp DNA ladders; Lanes 1 to 8 show T. b. brucei GUTat3.1, T. evansi IL3960, T. equiperdum IVM-t1, STIB818, STIB841, STIB842, BoTat1.1 strains and negative control (distilled water), respectively. (PPTX 164 kb

Trypanocidal Activity of 2,5-Diphenyloxazoles Isolated from the Roots of <i>Oxytropis lanata</i>

Eleven 2,5-diphenyloxazole derivatives (<b>1</b>–<b>11</b>), together with six known isoflavonoid derivatives, were isolated from the roots of <i>Oxytropis lanata</i>. The 2,5-diphenyloxazole (<b>1</b>) obtained proved to be identical to a standard sample used as a scintillator and liquid laser dye. The other oxazole derivatives isolated were found to have one to four hydroxy and/or <i>O</i>-methyl groups in their phenyl rings. Seven of the oxazole derivatives obtained are new (<b>3</b>–<b>9</b>). The inhibitory activity of the isolated compounds was evaluated against <i>Trypanosoma congolense</i>, the causative agent of African trypanosomosis in animals. Oxazoles with di- and trihydroxy groups showed trypanocidal activity, and 2-(2′,3′-dihydroxyphenyl)-5-(2″-hydroxyphenyl)­oxazole (<b>4</b>) exhibited the most potent inhibitory activity (IC₅₀ 1.0 μM)

İstiklal Savaşı'nda denizciler:Anadol'ya sevkiyat

Taha Toros Arşivi, Dosya Adı: Milli MücadeleUnutma İstanbul projesi İstanbul Kalkınma Ajansı'nın 2016 yılı "Yenilikçi ve Yaratıcı İstanbul Mali Destek Programı" kapsamında desteklenmiştir. Proje No: TR10/16/YNY/010