441 research outputs found

    Entropy and typical properties of Nash equilibria in two-player games

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    We use techniques from the statistical mechanics of disordered systems to analyse the properties of Nash equilibria of bimatrix games with large random payoff matrices. By means of an annealed bound, we calculate their number and analyse the properties of typical Nash equilibria, which are exponentially dominant in number. We find that a randomly chosen equilibrium realizes almost always equal payoffs to either player. This value and the fraction of strategies played at an equilibrium point are calculated as a function of the correlation between the two payoff matrices. The picture is complemented by the calculation of the properties of Nash equilibria in pure strategies.Comment: 6 pages, was "Self averaging of Nash equilibria in two player games", main section rewritten, some new results, for additional information see http://itp.nat.uni-magdeburg.de/~jberg/games.htm

    Study on Arctic Mining in Greenland

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    The Arctic region has a huge business potential and offers many possibilities, but to some extent, Arctic markets are not very familiar to most companies. It is therefore important to provide information about the markets, their characteristics and the operating context. This report gives an overview of the mining market and context in Greenland. Mining activities have so far been limited in Greenland considering the potential. A relatively weak record of mining activity appears to contrast with the metal endowment and existence of numerous mineral occurrences and several world class mineral deposits. Mineral exploration and mining in Greenland often occur in remote areas, usually far from existing infrastructure. This necessitates expensive transportation and establishment infrastructure. The remoteness, harsh Arctic climate and rugged terrain are negative factors often resulting in extra expenditures compared to most other jurisdictions. The many deep fjords in Greenland offer excellent opportunities for deep-sea port and shipping capacity. The social license to operate is in general very favourable in Greenland, and an ambitious new mineral strategy can be instrumental to attract new investments to mining in Greenland. Currently, Greenland is undergoing a phase of rapid development, and large government-funded infrastructure projects are in progress including new airports. Riikka Aaltonen, TEM, +358 295 064 216 Mikko Martikainen, TEM, +358 295 064 795 Pekka Tuomela, GTK, +358 50 300 563

    Statistical mechanics of random two-player games

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    Using methods from the statistical mechanics of disordered systems we analyze the properties of bimatrix games with random payoffs in the limit where the number of pure strategies of each player tends to infinity. We analytically calculate quantities such as the number of equilibrium points, the expected payoff, and the fraction of strategies played with non-zero probability as a function of the correlation between the payoff matrices of both players and compare the results with numerical simulations.Comment: 16 pages, 6 figures, for further information see http://itp.nat.uni-magdeburg.de/~jberg/games.htm

    Human 13N-ammonia PET studies: the importance of measuring 13N-ammonia metabolites in blood

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    Dynamic 13N-ammonia PET is used to assess ammonia metabolism in brain, liver and muscle based on kinetic modeling of metabolic pathways, using arterial blood 13N-ammonia as input function. Rosenspire et al. (1990) introduced a solid phase extraction procedure for fractionation of 13N-content in blood into 13N-ammonia, 13N-urea, 13N-glutamine and 13N-glutamate. Due to a radioactive half-life for 13N of 10 min, the procedure is not suitable for blood samples taken beyond 5–7 min after tracer injection. By modifying Rosenspire’s method, we established a method enabling analysis of up to 10 blood samples in the course of 30 min. The modified procedure was validated by HPLC and by 30-min reproducibility studies in humans examined by duplicate 13N-ammonia injections with a 60-min interval. Blood data from a 13N-ammonia brain PET study (from Keiding et al. 2006) showed: (1) time courses of 13N-ammonia fractions could be described adequately by double exponential functions; (2) metabolic conversion of 13N-ammonia to 13N-metabolites were in the order: healthy subjects > cirrhotic patients without HE > cirrhotic patients with HE; (3) kinetics of initial tracer distribution in tissue can be assessed by using total 13N-concentration in blood as input function, whereas assessment of metabolic processes requires 13N-ammonia measurements

    Éditorial

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    Introduction L’adoption de la Convention Européenne du Paysages (CEP) en 2000 constitue un événement clef dans la prise en compte des paysages au niveau européen. À ce jour, trente‐huit pays ont ratifié la Convention adoptée sous l’égide du Conseil de l’Europe. En spécifiant que le paysage est une composante essentielle du cadre de vie des Européens, la convention s’inscrit avant toute chose dans une dimension territoriale. Par ailleurs, un fondement fort de la CEP réside dans la particularit..

    A new approach of nonparametric estimation of incidence and lifetime risk based on birth rates and incident events

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    <p>Abstract</p> <p>Background</p> <p>Incidence and lifetime risk of diabetes are important public health measures. Traditionally, nonparametric estimates are obtained from survey data by means of a Nelson-Aalen estimator which requires data information on both incident events and risk sets from the entire cohort. Such data information is rarely available in real studies.</p> <p>Methods</p> <p>We compare two different approaches for obtaining nonparametric estimates of age-specific incidence and lifetime risk with emphasis on required assumptions. The first and novel approach only considers incident cases occurring within a fixed time window–we have termed this <it>cohort-of-cases </it>data–which is linked explicitly to the birth process in the past. The second approach is the usual Nelson-Aalen estimate which requires knowledge on observed time at risk for the entire cohort and their incident events. Both approaches are used on data on anti-diabetic medications obtained from Odense Pharmacoepidemiological Database, which covers a population of approximately 470,000 over the period 1993–2003. For both methods we investigate if and how incidence rates can be projected.</p> <p>Results</p> <p>Both the new and standard method yield similar sigmoidal shaped estimates of the cumulative distribution function of age-specific incidence. The Nelson-Aalen estimator gives somewhat higher estimates of lifetime risk (15.65% (15.14%; 16.16%) for females, and 17.91% (17.38%; 18.44%) for males) than the estimate based on cohort-of-cases data (13.77% (13.74%; 13.81%) for females, 15.61% (15.58%; 15.65%) for males). Accordingly the projected incidence rates are higher based on the Nelson-Aalen estimate–also too high when compared to observed rates. In contrast, the cohort-of-cases approach gives projections that fit observed rates better.</p> <p>Conclusion</p> <p>The developed methodology for analysis of cohort-of-cases data has potential to become a cost-effective alternative to a traditional survey based study of incidence. To allow more general use of the methodology, more research is needed on how to relax stationarity assumptions.</p
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