Open-source lab hardware: A versatile microfluidic control and sensor platform

Here we describe a completely integrated and customizable microfluidic control and sensing architecture that can be readily implemented for laboratory or portable chemical or biological control and sensing applications. The compact platform enables control of 32 solenoid valves, a multitude of pumps and motors, a thermo-electric controller, a pressure controller, and a high voltage power supply. It also features two temperature probe interfaces, one relative humidity and ambient temperature sensor, two pressure sensors, and interfaces to an electrical conductivity sensor, flow sensor, and a bubble detector. The platform can be controlled via an onboard microcontroller and requires no proprietary software. Keywords: Capillary electrophoresis; Chemical analysis; Fluidic sensing; Lab automation; Microfluidic sample handling; Valve controller

Open-source lab hardware: Driver and temperature controller for high compliance voltage, fiber-coupled butterfly lasers

This article describes the development of a compact, relatively low-cost, high compliance voltage laser driver that can provide the constant optical laser output required for a range of applications. The system contains an integrated, high-precision temperature controller that can be implemented with butterfly-style lasers containing an internal thermoelectric cooler. The laser parameters can be controlled manually or via an onboard microcontroller. Additionally, an adjustable over-current protection circuit safeguards the laser diode from potential damage

Importance of Vehicle Body Elements and Rear Axle Elements for Describing Road Booming Noise

For investigating influences of vehicle components on the acoustic comfort at low frequencies, e.g., the booming noise behavior of a vehicle, building a whole car simulation model is useful. To reduce the model’s complexity and to save resources in the validation process, we first identify relevant components before building the model. Based on previous studies, we focus on the vehicle’s body and the rear axle. In this paper, we analyze which axle and body elements are crucial for describing road booming noise. For this purpose, we use impact measurements to examine noise transfer functions of the body and a vibro-acoustical modal analysis to identify coupled modes between the body’s structure and the interior cavity. For investigating relevant force paths from the rear axle to the body, we used a chassis test bench. We identify the main transmission paths of road booming noise and highlight which axle and body components have an influence on them. Mainly the rear axle in its upright direction in combination with a rigid body movement of the rear tailgate coupled with the first longitudinal mode of the airborne cavity causes road booming noise. Furthermore, the rear axle steering, the active roll stabilization and the trim elements of the vehicle’s body are essential to describe road booming noise. The results can be used to set priorities in the validation of individual axle and body components for future simulation models. We found that the ventilation openings, the front seats, the headliner, and the cockpit of a vehicle have little influence on its noise transfer functions from the rear axle connection points to the driver’s ear between 20 and 60 Hz

Acoustic Processing of Fluidic Samples for Planetary Exploration

The search for life on other planetary bodies is driven by our quest to determine if Earth is unique with respect to harboring life. In order to answer this question, instrumentation with suitable sensitivity is required to measure biosignatures. In addition to accurate measurements by in-situ instruments, specialized sample acquisition and sample handling hardware is required to maximize the scientific information obtained from an acquired sample. This paper discusses a class of compact sample processing instrumentation using solid-state mechanisms that use acoustic waves to process samples prior to delivery to the instrument. Some of the acoustic sample processes that can be used to aid in preparation of liquid and liquid/solid mixtures include: mixing, milling, cavitating, lysing, heating, streaming, stirring, lofting, concentrating, segregating, and filtering. We will review these acoustic processes and show how they are generated using electromechanical systems. In addition to processing, these transduction systems could also use acoustics to interrogate physical properties such as the state of the sample, the acoustic velocity, and its attenuation. In order to generate these processes and sensing capabilities at these frequencies, a transduction mechanism is required to produce stress waves from electrical signals and vice versa. One commonly used technique is to use piezoelectric transducers that generate a stress that is linearly proportional to the voltage across the transducer and a voltage that is proportional to the stress on a transducer’s face. A variety of transducer modes are available to excite the sample, including thickness, transverse, radial, and shear extensional, and these can be used to build composite resonance structures including ultrasonic horns, tuning forks, bimorph, and unimorph benders to increase stress generated in the sample. We discuss how to model the acoustic interactions with the sample and the sample chamber in order to produce the required stress waves and illustrate the use of network models of piezoelectric transducers to accomplish this modeling. We demonstrate how to build up these models using Mason’s equivalent circuit for a piezoelectric and network models for acoustic layers in a design. Finally, to illustrate this acoustic processing ability, we will discuss a few systems that we have developed for sample handling systems for other planetary bodies like Mars and ocean worlds Enceladus and Europa

Status of the BELLE II Pixel Detector

The Belle II experiment at the super KEK B-factory (SuperKEKB) in Tsukuba, Japan, has been collecting $e^+e^−$ collision data since March 2019. Operating at a record-breaking luminosity of up to $4.7×10^{34} cm^{−2}s^{−1}$, data corresponding to $424 fb^{−1}$ has since been recorded. The Belle II VerteX Detector (VXD) is central to the Belle II detector and its physics program and plays a crucial role in reconstructing precise primary and decay vertices. It consists of the outer 4-layer Silicon Vertex Detector (SVD) using double sided silicon strips and the inner two-layer PiXel Detector (PXD) based on the Depleted P-channel Field Effect Transistor (DePFET) technology. The PXD DePFET structure combines signal generation and amplification within pixels with a minimum pitch of $(50×55) μm^2$. A high gain and a high signal-to-noise ratio allow thinning the pixels to $75 μm$ while retaining a high pixel hit efficiency of about $99$. As a consequence, also the material budget of the full detector is kept low at $≈0.21$$\frac{X}{X_0}$ per layer in the acceptance region. This also includes contributions from the control, Analog-to-Digital Converter (ADC), and data processing Application Specific Integrated Circuits (ASICs) as well as from cooling and support structures. This article will present the experience gained from four years of operating PXD; the first full scale detector employing the DePFET technology in High Energy Physics. Overall, the PXD has met the expectations. Operating in the intense SuperKEKB environment poses many challenges that will also be discussed. The current PXD system remains incomplete with only 20 out of 40 modules having been installed. A full replacement has been constructed and is currently in its final testing stage before it will be installed into Belle II during the ongoing long shutdown that will last throughout 2023

Raw Data for Publication: A Subcritical Water Extractor Prototype for Potential Astrobiology Spaceflight Mission

Raw Data for Publication: A Subcritical Water Extractor Prototype for Potential Astrobiology Spaceflight Missions. Includes pressure curve, heating curve, pH measurements, ORP measurements, conductivity measurements, electropherograms, total amino acid content, enantiomeric excess, force sensitive resistor calibration and measurements

Low Noise Adjustable Two-Stage Gain Transimpedance Amplifier with DC Offset

The project supports the paper: Cretu, V.F., Kehl, F., et al., Open-Source Lab Hardware: Low Noise Adjustable Two-Stage Gain Transimpedance Amplifier with DC Offset, in Elsevier HardwareX

Driver and Temperature Controller for High Compliance Voltage, Fiber-coupled Butterfly Lasers

Compact, relatively low-cost, high compliance voltage laser driver that can provide the extremely stable constant optical laser output required for a range of optical applications. The project supports the paper: Kehl, F., et al., Open-Source Lab Hardware: Driver and Temperature Controller for High Compliance Voltage, Fiber-coupled Butterfly Lasers, in Elsevier HardwareX

Microfluidic Control and Sensor Platform

MCSP is a completely integrated and customizable microfluidic control and sensing architecture that can be readily implemented for laboratory or portable chemical or biological control and sensing applications. The project supports the paper: Kehl, F., et al., Open-Source Lab Hardware: A Versatile Microfluidic Control and Sensor Platform, in Elsevier HardwareX