13 research outputs found
Mentoring and Individual Learning Plans: Issues of practice in a period of transition.
publication-status: Acceptedtypes: ArticleThis article draws upon research undertaken with 28 teacher education mentors,
managers and trainee teachers within the SW Centre for Excellence in Teacher
Training (CETT) in 2008, following the introduction of the new revised Lifelong
Learning UK (LLUK) standards. The first part of the article locates and contextualises
the policy context in relation to the school and further education (FE) sectors.
Two separate and distinctive models of mentoring practice are delineated, the first
model as a source of formative support for trainee teachers, and the second model
as a tool for the assessment of competence. The article concludes by suggesting
that the danger and indeed unintended consequence of separating out these functions
of mentoring is that an unnecessary dichotomy is created that dislocates
coherent teacher practices from one another. It argues that what is needed is a sustained
period of stability in the sector. This would leave a space for CETT professionals
and others to promote those practices that will make a difference not only
to the work of teacher educators but to the work of staff and students
Predictive integration of gene functional similarity and co-expression defines treatment response of endothelial progenitor cells
<p>Abstract</p> <p>Background</p> <p>Endothelial progenitor cells (EPCs) have been implicated in different processes crucial to vasculature repair, which may offer the basis for new therapeutic strategies in cardiovascular disease. Despite advances facilitated by functional genomics, there is a lack of systems-level understanding of treatment response mechanisms of EPCs. In this research we aimed to characterize the EPCs response to adenosine (Ado), a cardioprotective factor, based on the systems-level integration of gene expression data and prior functional knowledge. Specifically, we set out to identify novel biosignatures of Ado-treatment response in EPCs.</p> <p>Results</p> <p>The predictive integration of gene expression data and standardized functional similarity information enabled us to identify new treatment response biosignatures. Gene expression data originated from Ado-treated and -untreated EPCs samples, and functional similarity was estimated with Gene Ontology (GO)-based similarity information. These information sources enabled us to implement and evaluate an integrated prediction approach based on the concept of <it>k</it>-nearest neighbours learning (<it>k</it>NN). The method can be executed by expert- and data-driven input queries to guide the search for biologically meaningful biosignatures. The resulting <it>integrated kNN </it>system identified new candidate EPC biosignatures that can offer high classification performance (areas under the operating characteristic curve > 0.8). We also showed that the proposed models can outperform those discovered by standard gene expression analysis. Furthermore, we report an initial independent <it>in vitro </it>experimental follow-up, which provides additional evidence of the potential validity of the top biosignature.</p> <p>Conclusion</p> <p>Response to Ado treatment in EPCs can be accurately characterized with a new method based on the combination of gene co-expression data and GO-based similarity information. It also exploits the incorporation of human expert-driven queries as a strategy to guide the automated search for candidate biosignatures. The proposed biosignature improves the systems-level characterization of EPCs. The new integrative predictive modeling approach can also be applied to other phenotype characterization or biomarker discovery problems.</p
Public Reactions to Male Versus Female Terrorism: Experimental Evidence for the Male Warrior Hypothesis
The Evolutionary Significance of Red Sox Nation: Sport Fandom as a Byproduct of Coalitional Psychology
Sport fandom has received considerable attention from social scientists, yet few have considered it from an evolutionary perspective. To redress this gap, we develop the hypothesis that team sports exhibit characteristics that activate mechanisms which evolved to facilitate the development of coalitions in the context of small-scale warfare. Based on this by-product hypothesis, we predicted a correlation between fandom and binding (i.e. group-relevant) concerns, especially loyalty. To test this prediction, we administered the Sport Spectator Identification Scale (SSI) and the Moral Foundations Questionnaire (MFQ) to 495 undergraduates. The MFQ measures three binding concerns, including loyalty, and two individualizing ones, harm and fairness. As predicted, fandom correlated significantly with loyalty ( r = .27) and, within men, the two other binding concerns, authority ( r =.22) and purity ( r = .24). By contrast, fandom did not significantly correlate with harm or fairness. In addition, we predicted and found that men reported significantly higher levels of fandom (Cohen's d =.45) and loyalty ( d = .27) than did women. In conclusion, this study presents data supporting the coalitional by-product hypothesis of fandom and should spur further research using fandom as a window into our evolved psychology
Resonant α scattering of 6He: Limits of clustering in 10Be
The structure of 10Be was studied via resonant α-particle scattering of a neutron-rich 6He beam. A time projection chamber, PAT-TPC, was operated in an active-target mode to provide a gaseous 4He target and trace the beam and reaction products traversing its active tracking volume. This significantly lowered the detection threshold of reaction products at low energies. Elastic scattering, inelastic scattering to the 6He 2+ state, and the 6He(α, 2n)8Be reaction were measured below an energy of 6 MeV in the center-of-mass frame. Continuous spectra of excitation functions and angular distributions were obtained from unambiguously-identified recoiling α particles for the elastic and inelastic channels. While a resonance of the 4+ state at 10.15 MeV in 10Be previously reported was confirmed, no other resonances were identified in the elastic channel over the measured energy region. The results are in line with antisymmetric molecular dynamics calculations that predict the limits of α clustering in high-spin states due to a spin-orbit force
An examination of the internal consistency and structure of the Statistical Anxiety Rating Scale (STARS)
The impact of macro-economic circumstances and social protection expenditure on economic deprivation in 25 European countries, 2007-2011
Item does not contain fulltextIn this study, we investigate to what extent macro-economic circumstances and social protection expenditure affect economic deprivation. We use three items from round five of the European Social Survey (2010-2011) to construct our latent outcome variable, which we label economic deprivation in the 3 years before 2010-2011. The results of our linear multilevel regression analyses indicate that in countries that perform worse economically, individual experiences of economic deprivation are more prevalent: the stronger the rise in the unemployment rate and the lower a country's wealth, the more economic deprivation individuals experience. We also find that in countries with high levels of social protection, people experience less economic deprivation as compared to countries with low levels of social protection. In turn, adverse economic conditions in a country temper these positive outcomes of social welfare arrangements. Finally, our study reveals that the strength of the relationship between a low income and economic deprivation strongly varies according to the economic circumstances in a country and the generosity of the welfare state
A Bourdieusian approach to understanding employability: becoming a 'fish in water'
It is assumed in the current policy environment that higher education should lead to graduate employability, although understandings of employability are generally limited. In this paper we discuss issues relating to graduate employability with reference to a case study of an information technology (IT) student progressing to a graduate role in the IT industry. Our analysis uses Bourdieuâs âthinking toolsâ, habitus, field and capital, to discuss the importance to graduate employability of individual positions and dispositions, workplace culture and organisation, and the social contacts developed as part of undergraduate life. We argue that employability needs to be understood in relational terms. In particular, the value of skills and knowledge depends on the work and workplace to which a graduate progresses. Similarly, employable graduates need a âfeel for the gameâ
On the Evolution of Sport
Sports have received little attention from evolutionary biologists. I argue that sport began as a way for men to develop the skills needed in primitive hunting and warfare, then developed to act primarily as a lek where athletes display and male spectators evaluate the qualities of potential allies and rivals. This hypothesis predicts that (1) the most popular modern male sports require the skills needed for success in male-male physical competition and primitive hunting and warfare; (2) champion male athletes obtain high status and thereby reproductive opportunities in ways that parallel those gained by successful primitive hunters and warriors; (3) men pay closer attention than do women to male sports so they can evaluate potential allies and rivals; and (4) male sports became culturally more important when opportunities to evaluate potential allies and rivals declined as both the survival importance of hunting and the proportion of men who experience combat decreased. The characteristics of primitive and modern sports are more consistent with these predictions than those generated by intersexual sexual selection theories of sport