Is Web3 Better Than Web2 for Investors? Evidence from Domain Name Auctions

Blockchain-based assets are commonly believed to attract new investors. To investigate this claim, we compared investor preferences for Web2 and Web3 domain name auctions by analyzing daily auction patterns in Namecheap and OpenSea. Our results indicate that Web3 platforms may attract extreme investors with low or high values as a niche market. We found a significantly higher number of bids per auction, higher average bid prices, and greater price spreads on OpenSea, but a significantly lower number of unique bidders per auction. Our findings highlight the importance of considering the auction platform\u27s characteristics and asset context when evaluating bid patterns and predicting bid prices. This study serves as a starting point for future research in this emerging market and offers directions for further investigation

Sustainable Solution for Shoring Method of Cross-Creek Bridge in Ankeng MRT System in New Taipei City: A Case Study

In the Ankeng Light Rail MRT system (ALRMS) project, the U7 box girder passes crossing the Erbads creek and needs a temporary supporting system for the construction work.  In this study, three temporary shoring system options were proposed to be the construction method.  The D-B Contractor, New Asia construction and Development Corporation, evaluated and selected the optimal choice, The Steel truss frame with supporting beams, to serve as the temporary supporting system.  Compare the deflection of Δmax and Δactual, which are 1.609 cm and 1.59 cm, respectively.  This result presented that the shoring system composed of the H912*302*18*37 supporting beams and steel truss frame had achieved outstanding performance and work to construct the U7 box girder.  This paper presents how the three options are evaluated and the detailed construction processes along with the survey verification for the method

Poly[diaqua­(μ2-oxalato-κ4 O 1,O 2:O 1′,O 2′)(μ2-pyrazine-2-carboxyl­ato-κ4 N 1,O:O,O′)neodymium(III)]

In the title complex, [Nd(C5H3N2O2)(C2O4)(H2O)2]n, the NdIII atom is ten-coordinated by one N atom and three O atoms from two pyrazine-2-carboxyl­ate ligands, four O atoms from two oxalate ligands and two water mol­ecules in a distorted bicapped square-anti­prismatic geometry. The two crystallographically independent oxalate ligands, each lying on an inversion center, act as bridging ligands, linking Nd atoms into an extended zigzag chain. Neighboring chains are linked by the pyrazine-2-carboxyl­ate ligands into a two-dimensional layerlike network in the (10) plane. The layers are further connected by O—H⋯O and O—H⋯N hydrogen bonds, forming a three-dimensional supra­molecular network

TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases.

CD4+ Foxp3+ T regulatory (Treg) cells are key players in preventing lethal autoimmunity. Tregs undertake differentiation processes and acquire diverse functional properties. However, how Treg's differentiation and functional specification are regulated remains incompletely understood. Here, we report that gradient expression of TCF1 and LEF1 distinguishes Tregs into three distinct subpopulations, particularly highlighting a subset of activated Treg (aTreg) cells. Treg-specific ablation of TCF1 and LEF1 renders the mice susceptible to systemic autoimmunity. TCF1 and LEF1 are dispensable for Treg's suppressive capacity but essential for maintaining a normal aTreg pool and promoting Treg's competitive survival. As a consequence, the development of T follicular regulatory (Tfr) cells, which are a subset of aTreg, is abolished in TCF1/LEF1-conditional knockout mice, leading to unrestrained T follicular helper (Tfh) and germinal center B cell responses. Thus, TCF1 and LEF1 act redundantly to control the maintenance and functional specification of Treg subsets to prevent autoimmunity