82 research outputs found

    Experimental and theoretical diagnoses of yearly-scale nitrate ion spikes observed in a Dome Fuji shallow ice core

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    第3回極域科学シンポジウム 横断セッション「海・陸・氷床から探る後期新生代の南極寒冷圏環境変動」11月27日(火) 国立国語研究所 2階講

    Elucidating colorectal cancer-associated bacteria through profiling of minimally perturbed tissue-associated microbiota

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    Sequencing-based interrogation of gut microbiota is a valuable approach for detecting microbes associated with colorectal cancer (CRC); however, such studies are often confounded by the effect of bowel preparation. In this study, we evaluated the viability of identifying CRC-associated mucosal bacteria through centimeter-scale profiling of the microbiota in tumors and adjacent noncancerous tissue from eleven patients who underwent colonic resection without preoperative bowel preparation. High-throughput 16S rRNA gene sequencing revealed that differences between on- and off-tumor microbiota varied considerably among patients. For some patients, phylotypes affiliated with genera previously implicated in colorectal carcinogenesis, as well as genera with less well-understood roles in CRC, were enriched in tumor tissue, whereas for other patients, on- and off-tumor microbiota were very similar. Notably, the enrichment of phylotypes in tumor-associated mucosa was highly localized and no longer apparent even a few centimeters away from the tumor. Through short-term liquid culturing and metagenomics, we further generated more than one-hundred metagenome-assembled genomes, several representing bacteria that were enriched in on-tumor samples. This is one of the first studies to analyze largely unperturbed mucosal microbiota in tissue samples from the resected colons of unprepped CRC patients. Future studies with larger cohorts are expected to clarify the causes and consequences of the observed variability in the emergence of tumor-localized microbiota among patients

    A Model for the 3He(\vec d, p)4He Reaction at Intermediate Energies

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    Polarization correlation coefficients have been measured atRIKEN for the \vec 3He(\vec d,p)4He reaction at intermediate energies. We propose a model for the (\vec d, p) reaction mechanism using the pd elastic scattering amplitude which is rigorously determined by a Faddeev calculation and using modern NN forces. Our theoretical predictions for deuteron polarization observables A_y, A_{yy}, A_{xx} and A_{xz} at E_d=140, 200 and 270 MeV agree qualitatively in shape with the experimental data for the reaction 3He(\vec d,p)4He.Comment: 6 pages, 11 figures, 1 table, reference: http://www.phys.ntu.edu.tw/english/fb16/contribution/topic4/Uesaka_Tomohiro1. ps in Contribution for the XVIth IUPAP International Conference on Few-Body Problems in Physics, (Taipei, Taiwan 6-11, March 2000

    Subaru Hyper Suprime-Cam Survey for An Optical Counterpart of GW170817

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    We perform a zz-band survey for an optical counterpart of a binary neutron star coalescence GW170817 with Subaru/Hyper Suprime-Cam. Our untargeted transient search covers 23.623.6 deg2^2 corresponding to the 56.6%56.6\% credible region of GW170817 and reaches the 50%50\% completeness magnitude of 20.620.6 mag on average. As a result, we find 60 candidates of extragalactic transients, including J-GEM17btc (a.k.a. SSS17a/DLT17ck). While J-GEM17btc is associated with NGC 4993 that is firmly located inside the 3D skymap of GW170817, the other 59 candidates do not have distance information in the GLADE v2 catalog or NASA/IPAC Extragalactic Database (NED). Among 59 candidates, 58 are located at the center of extended objects in the Pan-STARRS1 catalog, while one candidate has an offset. We present location, zz-band apparent magnitude, and time variability of the candidates and evaluate the probabilities that they are located inside of the 3D skymap of GW170817. The probability for J-GEM17btc is 64%64\% being much higher than those for the other 59 candidates (9.3×1032.1×101%9.3\times10^{-3}-2.1\times10^{-1}\%). Furthermore, the possibility, that at least one of the other 59 candidates is located within the 3D skymap, is only 3.2%3.2\%. Therefore, we conclude that J-GEM17btc is the most-likely and distinguished candidate as the optical counterpart of GW170817.Comment: 14 pages, 9 figures. Accepted for publication in PASJ (Publications of the Astronomical Society of Japan

    看護教育に携帯電話を活用した参画支援ソフトウェア”ECILS”によるeラーニングの試案

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    看護教育において、株式会社エネックスが開発した携帯電話を利用した参画支援ソフトウェア“ECILS”を活用するシステムを試案した。 “ECILS”の機能は①リアルタイムアンケート集計、②メッセージコミュニケーション、③出席管理、④簡易理解度測定(小テスト)、⑤課題提出、⑥連絡網、⑦メッセージ検索である。“ECILS"をうまく活用することで、学生の学習意欲の向上が期待でき、参画力が身に付くことが推察される。携帯電話による利便性から情報管理や情報活用の広がりがあり、教員の授業支援と教育力向上に寄与するシステムでもある
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