60 research outputs found
Stroboscopic Time-of-Flight Neutron Diffraction in Long Pulsed Magnetic Fields
We present proof-of-principle experiments of stroboscopic time-of-flight
(TOF) neutron diffraction in long pulsed magnetic fields. By utilizing electric
double-layer capacitors, we developed a long pulsed magnet for neutron
diffraction measurements, which generates pulsed magnetic fields with the full
widths at the half maximum of more than ms. The field variation is slow
enough to be approximated as a steady field within the time scale of a
polychromatic neutron pulse passing through a sample placed in a distance of
the order of m from the neutron source. This enables us to efficiently
explore the reciprocal space using a wide range of neutron wavelength in high
magnetic fields. We applied this technique to investigate field-induced
magnetic phases in the triangular lattice antiferromagnets
CuFeGaO ().Comment: 9 pages, 7 figure
Pain following COVID-19 vaccination
Pain at the injection site is the most frequent reaction among COVID-19 vaccine recipients, but its characteristics were not fully described yet. The purpose of this study was to investigate multiple domains of pain following BNT162b2 mRNA vaccination. We included 107 subjects undergoing primary shot of the vaccination twice into deltoid muscle with a 3-week interval. They completed 6 sessions of pain assessments, one before the first and second dose (1-0, 2-0), and 1st / 7th day after the first and second dose (1-1 / 1-7, 2-1 / 2-7). Pain visual analog scale (VAS), pain distribution, and pressure pain threshold (PPT) on deltoid muscle were evaluated in each session. The mean VAS (at rest / shoulder motion) was 6.0 / 27.6 mm at 1-1, and 12.8 / 34.0 mm at 2-1. Approximately, 90% of recipients showed localized pain within the upper arm. Percentage change of PPTs at 1-1 and 2-1 was bilaterally (ipsilateral / contralateral) decreased to 87.4 / 89.4% and 80.6 / 91.0%, which was recovered to the baseline level at 1-7 and 2-7. Temporary, mild-to-moderate intensity, localized distribution, concomitant with bilateral mechanical hyperalgesia on the deltoid muscle, were typical pain characteristics following this vaccination. These findings provide a rationale that will be informative for future recipients
Feasibility of Intraspecific Mix Cropping in Japan-Trials with Soybean Lines in Kawatabi Field Center
Young Researchers Sessio
BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.
Branched-chain amino acid (BCAA; valine, leucine and isoleucine) supplementation is often beneficial to energy expenditure; however, increased circulating levels of BCAA are linked to obesity and diabetes. The mechanisms of this paradox remain unclear. Here we report that, on cold exposure, brown adipose tissue (BAT) actively utilizes BCAA in the mitochondria for thermogenesis and promotes systemic BCAA clearance in mice and humans. In turn, a BAT-specific defect in BCAA catabolism attenuates systemic BCAA clearance, BAT fuel oxidation and thermogenesis, leading to diet-induced obesity and glucose intolerance. Mechanistically, active BCAA catabolism in BAT is mediated by SLC25A44, which transports BCAAs into mitochondria. Our results suggest that BAT serves as a key metabolic filter that controls BCAA clearance via SLC25A44, thereby contributing to the improvement of metabolic health
Species Difference in Sensitivity of Human and Mouse P2X7 Receptors to Inhibitory Effects of Divalent Metal Cations
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