16,769 research outputs found
Keeping your eye on the rail: gaze behaviour of horse riders approaching a jump
The gaze behaviour of riders during their approach to a jump was investigated using a mobile eye tracking device (ASL Mobile Eye). The timing, frequency and duration of fixations on the jump and the percentage of time when their point of gaze (POG) was located elsewhere were assessed. Fixations were identified when the POG remained on the jump for 100 ms or longer. The jumping skill of experienced but non-elite riders (n=10) was assessed by means of a questionnaire. Their gaze behaviour was recorded as they completed a course of three identical jumps five times. The speed and timing of the approach was calculated. Gaze behaviour throughout the overall approach and during the last five strides before take-off was assessed following frame-by-frame analyses. Differences in relation to both round and jump number were found. Significantly longer was spent fixated on the jump during round 2, both during the overall approach and during the last five strides (p , 0.05). Jump 1 was fixated on significantly earlier and more frequently than jump 2 or 3 (p , 0.05). Significantly more errors were made with jump 3 than with jump 1 (p=0.01) but there was no difference in errors made between rounds
Simulation of cell movement through evolving environment: a fictitious domain approach
A numerical method for simulating the movement of unicellular organisms which respond to chemical signals is presented. Cells are modelled as objects of finite size while the extracellular space is described by reaction-diffusion partial differential equations. This modular simulation allows the implementation of different models at the different scales encountered in cell biology and couples them in one single framework. The global computational cost is contained thanks to the use of the fictitious domain method for finite elements, allowing the efficient solve of partial differential equations in moving domains. Finally, a mixed formulation is adopted in order to better monitor the flux of chemicals, specifically at the interface between the cells and the extracellular domain
Continuity of symplectically adjoint maps and the algebraic structure of Hadamard vacuum representations for quantum fields on curved spacetime
We derive for a pair of operators on a symplectic space which are adjoints of
each other with respect to the symplectic form (that is, they are sympletically
adjoint) that, if they are bounded for some scalar product on the symplectic
space dominating the symplectic form, then they are bounded with respect to a
one-parametric family of scalar products canonically associated with the
initially given one, among them being its ``purification''. As a typical
example we consider a scalar field on a globally hyperbolic spacetime governed
by the Klein-Gordon equation; the classical system is described by a symplectic
space and the temporal evolution by symplectomorphisms (which are
symplectically adjoint to their inverses). A natural scalar product is that
inducing the classical energy norm, and an application of the above result
yields that its ``purification'' induces on the one-particle space of the
quantized system a topology which coincides with that given by the two-point
functions of quasifree Hadamard states. These findings will be shown to lead to
new results concerning the structure of the local (von Neumann)
observable-algebras in representations of quasifree Hadamard states of the
Klein-Gordon field in an arbitrary globally hyperbolic spacetime, such as local
definiteness, local primarity and Haag-duality (and also split- and type
III_1-properties). A brief review of this circle of notions, as well as of
properties of Hadamard states, forms part of the article.Comment: 42 pages, LaTeX. The Def. 3.3 was incomplete and this has been
corrected. Several misprints have been removed. All results and proofs remain
unchange
Brick Walls and AdS/CFT
We discuss the relationship between the bulk-boundary correspondence in
Rehren's algebraic holography (and in other 'fixed-background' approaches to
holography) and in mainstream 'Maldacena AdS/CFT'. Especially, we contrast the
understanding of black-hole entropy from the viewpoint of QFT in curved
spacetime -- in the framework of 't Hooft's 'brick wall' model -- with the
understanding based on Maldacena AdS/CFT. We show that the brick-wall
modification of a Klein Gordon field in the Hartle-Hawking-Israel state on
1+2-Schwarzschild AdS (BTZ) has a well-defined boundary limit with the same
temperature and entropy as the brick-wall-modified bulk theory. One of our main
purposes is to point out a close connection, for general AdS/CFT situations,
between the puzzle raised by Arnsdorf and Smolin regarding the relationship
between Rehren's algebraic holography and mainstream AdS/CFT and the puzzle
embodied in the 'correspondence principle' proposed by Mukohyama and Israel in
their work on the brick-wall approach to black hole entropy. Working on the
assumption that similar results will hold for bulk QFT other than the Klein
Gordon field and for Schwarzschild AdS in other dimensions, and recalling the
first author's proposed resolution to the Mukohyama-Israel puzzle based on his
'matter-gravity entanglement hypothesis', we argue that, in Maldacena AdS/CFT,
the algebra of the boundary CFT is isomorphic only to a proper subalgebra of
the bulk algebra, albeit (at non-zero temperature) the (GNS) Hilbert spaces of
bulk and boundary theories are still the 'same' -- the total bulk state being
pure, while the boundary state is mixed (thermal). We also argue from the
finiteness of its boundary (and hence, on our assumptions, also bulk) entropy
at finite temperature, that the Rehren dual of the Maldacena boundary CFT
cannot itself be a QFT and must, instead, presumably be something like a string
theory.Comment: 54 pages, 3 figures. Arguments strengthened in the light of B.S. Kay
`Instability of Enclosed Horizons' arXiv:1310.739
Quantum Chinos Game: winning strategies through quantum fluctuations
We apply several quantization schemes to simple versions of the Chinos game.
Classically, for two players with one coin each, there is a symmetric stable
strategy that allows each player to win half of the times on average. A partial
quantization of the game (semiclassical) allows us to find a winning strategy
for the second player, but it is unstable w.r.t. the classical strategy.
However, in a fully quantum version of the game we find a winning strategy for
the first player that is optimal: the symmetric classical situation is broken
at the quantum level.Comment: REVTEX4.b4 file, 3 table
Historical-institutionalist perspectives on the development of the EU budget system
The EU budget has only recently started to feature in theories of European integration. Studies typically adopt a historical-institutionalist framework, exploring notions such as path dependency. They have, however, generally been rather aggregated, or coarse-grained, in their approach. The EU budget has thus been treated as a single entity rather than a series of inter-linked institutions. This paper seeks to address these lacunae by adopting a fine-grained approach. This enables us to emphasize the connections that exist between EU budgetary institutions, in both time and space. We show that the initial set of budgetary institutions was unable, over time, to achieve consistently their treaty-based objectives. In response, rather than reform these institutions at potentially high political cost, additional institutions were layered on top of the extant structures. We thus demonstrate how some EU budgetary institutions have remained unchanged, whilst others have been added or changed over time
The N-Terminus of Apolipoprotein A-V Adopts a Helix-Bundle Molecular Architecture
Previous studies of recombinant full-length human apolipoprotein A-V (apoA-V) provided evidence of the presence of two independently folded structural domains. Computer-assisted sequence analysis and limited proteolysis studies identified an N-terminal fragment as a candidate for one of the domains. C-Terminal truncation variants in this size range, apoA-V(1-146) and apoA-V(1-169), were expressed in Escherichia coli and isolated. Unlike full-length apoA-V or apoA-V(1-169), apoA-V(1-146) was soluble in neutral-pH buffer in the absence of lipid. Sedimentation equilibrium analysis yielded a weight-average molecular weight of 18811, indicating apoA-V(1-146) exists as a monomer in solution. Guanidine HCl denaturation experiments at pH 3.0 yielded a one-step native to unfolded transition that corresponds directly with the more stable component of the two-stage denaturation profile exhibited by full-length apoA-V. On the other hand, denaturation experiments conducted at pH 7.0 revealed a less stable structure. In a manner similar to that of known helix bundle apolipoproteins, apoA-V(1-146) induced a relatively small enhancement in 8-anilino-1-naphthalenesulfonic acid fluorescence intensity. Quenching studies with single-Trp apoA-V(1-146) variants revealed that a unique site predicted to reside on the nonpolar face of an amphipathic R-helix was protected from quenching by KI. Taken together, the data suggest the 146 N-terminal residues of human apoA-V adopt a helix bundle molecular architecture in the absence of lipid and, thus, likely exist as an independently folded structural domain within the context of the intact protein
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