Statistical mechanical evaluation of spread spectrum watermarking model with image restoration

In cases in which an original image is blind, a decoding method where both the image and the messages can be estimated simultaneously is desirable. We propose a spread spectrum watermarking model with image restoration based on Bayes estimation. We therefore need to assume some prior probabilities. The probability for estimating the messages is given by the uniform distribution, and the ones for the image are given by the infinite range model and 2D Ising model. Any attacks from unauthorized users can be represented by channel models. We can obtain the estimated messages and image by maximizing the posterior probability. We analyzed the performance of the proposed method by the replica method in the case of the infinite range model. We first calculated the theoretical values of the bit error rate from obtained saddle point equations and then verified them by computer simulations. For this purpose, we assumed that the image is binary and is generated from a given prior probability. We also assume that attacks can be represented by the Gaussian channel. The computer simulation retults agreed with the theoretical values. In the case of prior probability given by the 2D Ising model, in which each pixel is statically connected with four-neighbors, we evaluated the decoding performance by computer simulations, since the replica theory could not be applied. Results using the 2D Ising model showed that the proposed method with image restoration is as effective as the infinite range model for decoding messages. We compared the performances in a case in which the image was blind and one in which it was informed. The difference between these cases was small as long as the embedding and attack rates were small. This demonstrates that the proposed method with simultaneous estimation is effective as a watermarking decoder

Delayed Cell Cycle Progression and Apoptosis Induced by Hemicellulase-Treated Agaricus blazei

We examined the effects of hemicellulase-treated Agaricus blazei (AB fraction H, ABH) on growth of several tumor cell lines. ABH inhibited the proliferation of some cell lines without cytotoxic effects. It markedly prolonged the S phase of the cell cycle. ABH also induced mitochondria-mediated apoptosis in different cell lines. However, it had no impact on the growth of other cell lines. ABH induced strong activation of p38 mitogen-activated protein kinase (MAPK) in the cells in which it evoked apoptosis. On the other hand, ABH showed only a weak p38 activation effect in those cell lines in which it delayed cell cycle progression with little induction of apoptosis. However, p38 MAPK-specific inhibitor inhibited both ABH-induced effects, and ABH also caused apoptosis in the latter cells under conditions of high p38 MAPK activity induced by combined treatment with TNF-α. These results indicate that the responsiveness of p38 MAPK to ABH, which differs between cell lines, determines subsequent cellular responses on cell growth

Bifurcation analysis in an associative memory model

We previously reported the chaos induced by the frustration of interaction in a non-monotonic sequential associative memory model, and showed the chaotic behaviors at absolute zero. We have now analyzed bifurcation in a stochastic system, namely a finite-temperature model of the non-monotonic sequential associative memory model. We derived order-parameter equations from the stochastic microscopic equations. Two-parameter bifurcation diagrams obtained from those equations show the coexistence of attractors, which do not appear at absolute zero, and the disappearance of chaos due to the temperature effect.Comment: 19 page

アミロイド前駆体タンパク質のプロセッシングにおけるO型糖鎖の役割

首都大学東京, 2016-09-30, 博士（理学）首都大学東

アワアイ ニ ガンユウ サレル ユウヨウ ビリョウ セイブン ノ ユウコウ リヨウ ニ カンスル ケンキュウ

This study is aiming at development of the synthetic methods of the active fine ingredients containing in Awa indigo Plant (Awa-ai). The long tradition of the indigo dyeing is prevailing over a thousand year here in the Tokushima Prefecture, and historically the Ai-leaf had been sold in Kansai area about 550 years ago. Although our concern on the Ai-leaf used to be centered on a dyeing stuff, several biologically active ingredients have been reported recently contained in the Awa Indigo Plant. We have, therefore, been interested in these fine ingredients and here wish to develop the efficient and ecofriendly synthetic methods of such remarkable ingredients. The synthetic methods reported here are the methods activated by microwave (MW) irradiation and photoirradiation of the ultraviolet light (UV)