A unified data flow model for fault tolerant computers

The Dataflow Simulation System (DFSS) at USL was used as the medium on which a functional simulaton of sIFT was produced. DFSS is written in PL/I and is supported by MULTICS. Within the simulation, all the interprocessor communication, fault simulation, system state data, and monitoring were implemented in dataflow and supported directly by DFSS. The actual processor level computation was carried out by the SIFT code in PASCAL. The interface between DFSS in PL/I and the SIFT code in PASCAL was supported under a mechanism in DFSS called a Node Realization Module (NRM)

Drosophila KDM2 is a H3K4me3 demethylase regulating nucleolar organization

<p>Abstract</p> <p>Background</p> <p>CG11033 (dKDM2) is the <it>Drosophila </it>homolog of the gene KDM2B. dKDM2 has been known to possess histone lysine demethylase activity towards H3K36me2 in cell lines and it regulates H2A ubiquitination. The human homolog of the gene has dual activity towards H3K36me2 as well as H3K4me3, and plays an important role in cellular senescence.</p> <p>Findings</p> <p>We have used transgenic flies bearing an RNAi construct for the dKDM2 gene. The knockdown of dKDM2 gene was performed by crossing UAS-RNAi-dKDM2 flies with actin-Gal4 flies. Western blots of acid extracted histones and immunofluoresence analysis of polytene chromosome showed the activity of the enzyme dKDM2 to be specific for H3K4me3 in adult flies. Immunofluoresence analysis of polytene chromosome also revealed the presence of multiple nucleoli in RNAi knockdown mutants of dKDM2 and decreased H3-acetylation marks associated with active transcription.</p> <p>Conclusion</p> <p>Our findings indicate that dKDM2 is a histone lysine demethylase with specificity for H3K4me3 and regulates nucleolar organization.</p

Effect of growth regulators and Physiological Gradients on the High frequency plant regeneration from the long-term callus cultures of different germplasms of Rice (Oryza sativa L.)

Callus cultures of rice were initiated from mature embryos of different cultivars on LS medium containing 2 mg/L 2,4-D. Increasing concentrations of 2,4-D and 2,4-5T also increased the frequency of callus initiation in all the cultivars tested. Of different cultivars, Tellahamsa was found to be superior for callus initiation. Genotypic differences for plant regeneration were also observed. Cultivar Tellahamsa showed the highest (65-75%) frequency of plant differentiation followed by DGWG, Yerragaluvadlu, Surekha, Basmati-370, Bala, Chakko amubi, Jaya and IR-8. Callus cultures of rice cultivar Bala grown on a shoot-forming medium (LS + 1 mg/L IAA + 4 mg/L KN + 2% sucrose) were exposed to gibberellic acid and abscisic acid for varying lengths of time and at different periods during culture. Gibberellic acid totally suppressed the organogenesis in callus cultures of rice. The results suggest that if the tissue accumulated sufficient gibberellic acid prior to the initiation of meristemoids and shoot primordia, repression of shoot formation occurred. This repression was not reversed by increasing the levels of IAA and KN in the medium, but abscisic acid could partially overcome the gibberellic acid repression of shoot formation in rice callus. It has been observed in rice that shoots usually emerge from the basal portions of callus. This observation suggested that perhaps physiological gradients of materials were operative during the organ initiation process. To test this hypothesis, starch content and the enzyme activity of malate dehydrogenase in upper and lower portions of shoot-forming and non-shoot-forming callus were determined. Starch began to accumulate in both upper and lower portions of the shoot forming tissues within 4 days of culture. The rate of accumulation however, was faster and more in the lower portion of the callus leading to a peak of accumulation on day 8 in culture, i.e., prior to shoot formation. Non-shoot-forming callus cultures accumulated little starch during the same period of culture. Malate dehydrogenase (MDH) activity was examined in order to know the overall rate of respiration. In the upper segment of shoot-forming callus, the activity of MDH was very high by day 4 but declined continuously thereafter. The rate of activity of the enzyme was significantly higher beyond four days in culture in case of the lower portion of the shoot forming callus. Enzyme activity was lower in the non-shoot-forming portions (both upper and lower) of the callus. The higher rate of enzyme activity for the upper portion of the tissue could be attributed to increased oxygen availability. Thus, the evidence for the idea that concentrations of gradients or physiological gradients of substances into the callus tissue may be the operative factors promoting organ initiation in vitro is presented

Energy Aware Heuristic approach for Cluster Head Selection in Wireless Sensor Networks

Wireless sensor networks idea is envisioned and defined as self-deployed, error prone, long living inexpensive communication devices that are densely deployed to collect data from physical space. Sensor nodes communicate with each other to detect events depending on the application, to collect and process data, and to transmit the sensed information to the base station by hopping the data from node to node. Major challenge in wireless network is energy consumption, since the sensor devices are deployed on unattended wide areas and replacing their batteries is not very feasible. Therefore, designing energy-aware algorithms becomes a major challenge for extending the lifetime of sensors. The lifetime of the network can be maximized by selecting the most optimal cluster head. In this paper, a heuristic decision making approach is proposed for producing energy-aware clusters with optimal selection of cluster head. This helps to improve the efficiency and accuracy and overcome the drawbacks like getting trapped at a local extreme in the optimization process

Genome-wide identification and transcriptional profiling of small heat shock protein gene family under diverse abiotic stress conditions in Sorghum bicolor (L.)

The small heat shock proteins (sHsps/Hsp20s) are the molecular chaperones that maintain proper folding, trafficking and disaggregation of proteins under diverse abiotic stress conditions. In the present investigation, a genome-wide scan revealed the presence of a total of 47 sHsps in Sorghum bicolor (SbsHsps), distributed across 10 subfamilies, the major subfamily being P (plastid) group with 17 genes. Chromosomes 1 and 3 appear as the hot spot regions for SbsHsps, and majority of them were found acidic, hydrophilic, unstable and intron less. Interestingly, promoter analysis indicated that they are associated with both biotic and abiotic stresses, as well as plant development. Sorghum sHsps exhibited 15 paralogous and 20 orthologous duplications. Expression analysis of 15 genes selected from different subfamilies showed high transcript levels in roots and leaves implying that they are likely to participate in the developmental processes. SbsHsp genes were highly induced by diverse abiotic stresses inferring their critical role in mediating the environmental stress responses. Gene expression data revealed that SbsHsp-02 is a candidate gene expressed in all the tissues under varied stress conditions tested. Our results contribute to the understanding of the complexity of SbsHsp genes and help to analyse them further for functional validation

The Influence of Walking Speed and Heel Height on Peak Plantar Pressure in the Forefoot of Healthy Adults: A Pilot Study

Article number: 1000239Background: The body of empirical research is suggestive of the fact that faster walking speed and increasing heel height can both give rise to elevated plantar pressures. However, there is little evidence of the interaction between walking speed and heel height on changes in plantar pressure. Therefore, the aim of this study was to investigate whether the effect of heel height on plantar pressure is the same for different walking speeds Methodology: Eighteen healthy adults, between the ages of 18 and 35 were assessed for changes in peak plantar pressure at walking speeds of 0.5 mph, 0.8 mph, 1.4 mph and 2.4 mph on a treadmill, wearing heels of 2 cm, 3 cm, 6 cm and 9 cm. Both the speed of walking and heels were randomly assigned to each participant. Peak plantar pressure values were determined in the forefoot region using the F-scan system which made use of in-shoe insoles. Data were analysed using two-way ANOVA. Results: Increasing heel height and walking speed resulted in significantly higher peak plantar pressure in the forefoot. Post-hoc analysis also confirmed the findings of two-way ANOVA of significant increase in peak plantar pressure with increments in heel height and walking speed. The two-way ANOVA illustrated significantly higher peak plantar pressures in both the forefeet due to interaction of walking speed and increasing heel heights. Conclusion: This study suggests that an interaction of walking speed and footwear design on distribution of plantar pressure exists. Therefore it is necessary to standardize walking speed and shoe design in future studies evaluating plantar pressures.sch_physch_pod5pub4758pub

Smart Wearable Gadget for Miners Using IOT

Safety is the most important part of any kind of assiduity is safety. In extreme circumstances, safety-related negligence could result in the destruction of expensive clothing or the loss of human life. Every min-ing diligence adhere to a few basic preventative measures in order to avoid any generally unwelcome wonders. The most important component at this time is communication in order to continuously monitor various pa-rameters and take the appropriate actions as a result to avoid any risks linked with the product or the management of mortal funds. A stable and wide-range effective communication system between personnel in the mine and the control centre must be built in order to increase safety in un-derground mines. The cable communication network technology is inef-fective within underground mines. Here we can tackle the matter of acci-dents which end with death of several people per annum. It is discovered that the speed of fatality within the coal pit industry is almost six times the speed for all private industries. And most of those accidents are because of toxic gases, fires, and a lack of rescue systems. By implementing mine surveillance gadgets, which may be used within the mine and detect the number of various gases, fall, emergency detection and report to them. This article focuses on the design and analysis of the smart wearable gadget for miners in the mining industry using IoT

Occupational Exposures Among Hair and Nail Salon Workers: a Scoping Review

PURPOSE OF REVIEW: To review the literature published from 2014 to 2019 on hair and nail salon workers concerning exposure assessment, reproductive and respiratory endpoints, and endocrine disruption, in relation to workplace exposures. RECENT FINDINGS: We identified 29 relevant peer-reviewed publications. Overall, there were insufficient studies to determine whether working in these settings is associated with reproductive health endpoints, although prior studies suggest that reproductive effects are of concern. There is consistent evidence that working in hair and nail salons may increase the risk of respiratory effects. Also, despite the fact that many hair and nail care products contain endocrine disrupting compounds, no recent studies have evaluated endocrine-related endpoints. Moreover, few studies have evaluated chemical exposures in these settings and biomonitoring studies are sparse. SUMMARY: Improved exposure assessment of chemical hazards in hair and nail salons is necessary to properly characterize occupational exposures and assess their potential health risks. Further studies on endpoints related to endocrine disruption and reproductive health outcomes among hair and nail salon workers are needed. Improved exposure and epidemiologic studies will help inform chemical exposure mitigation efforts in a vulnerable occupational population, as well as policies related to workplace and consumer product safet

Pattern of genetic inheritance of morphological and agronomic traits of sorghum associated with resistance to sorghum shoot fly, Atherigona soccata

Sorghum shoot fly, Atherigona soccata is an important pest of sorghum during the seedling stage, which influences both fodder and grain yield. To understand the nature of inheritance of shoot fly resistance in sorghum, we performed generation mean analysis using two crosses IS 18551 × Swarna and M 35-1 × ICSV 700 during the 2013–2014 cropping seasons. The F1, F2, BC1 and BC2 progenies, along with the parental lines were evaluated for agronomic and morphological traits associated with resistance/susceptibility to sorghum shoot fly, A. soccata. The cross IS 18551 × Swarna exhibited significant differences between the parents for shoot fly deadhearts (%) in the postrainy season. The progenies of this cross exhibited lower shoot fly damage, suggesting that at least one of the parents should have genes for resistance to develop shoot fly-resistant hybrids. Leaf glossiness, leafsheath pigmentation and plant vigor score during the seedling stage exhibited non-allelic gene interactions with dominant gene action, whereas 100 seed weight showed both additive and dominant gene interactions. Presence of awns showed recessive nature of the awned gene. Generation mean analysis suggested that both additive and dominance gene effects were important for most of the traits evaluated in this study, but dominance had a more pronounced effect