1,107 research outputs found
Comparison of structural magnetic resonance imaging findings between neuropsychiatric systemic lupus erythematosus and systemic lupus erythematosus patients: A systematic review and meta-analysis
Introduction:
Neuropsychiatric systemic lupus erythematosus is often clinically challenging to diagnose, treat and monitor. Although brain magnetic resonance imaging is frequently performed before lumbar puncture in neuropsychiatric systemic lupus erythematosus, it is not clear from the literature whether specific brain magnetic resonance imaging findings are associated with distinct clinical features of neuropsychiatric systemic lupus erythematosus.
Methods:
We conducted a systematic review and meta-analysis on published studies of neuropsychiatric systemic lupus erythematosus including brain magnetic resonance imaging and the 1999 American College of Rheumatology-defined clinical neuropsychiatric systemic lupus erythematosus syndromes to determine their relationship. Pooled prevalence and risk ratio for distinct neuropsychiatric systemic lupus erythematosus associations were determined with 95% confidence intervals.
Results:
Of 821 studies screened, 21 fulfilled inclusion criteria. A total of 818 participants were evaluated (91% female) with 1064 neuropsychiatric systemic lupus erythematosus episodes assessed. Neuropsychiatric systemic lupus erythematosus features included headache (24%), seizures (19%), cerebrovascular disease (18%), cognitive dysfunction (15%) and acute confusional state (14%). Normal magnetic resonance imaging was significant for anxiety disorder (risk ratio: 9.00; 95% confidence interval: 2.40, 33.79), autonomic disorder (risk ratio: 7.00; 95% confidence interval: 0.51, 96.06) and plexopathy (risk ratio: 5.00; 95% confidence interval: 0.81, 31.00). Highest risk ratio of neuropsychiatric systemic lupus erythematosus syndrome with abnormal magnetic resonance imaging was observed for cerebrovascular disease (risk ratio: 0.15; 95% confidence interval: 0.10, 0.24) and demyelination (risk ratio: 0.11; 95% confidence interval: 0.02, 0.72).
Conclusion:
Normal magnetic resonance imaging in neuropsychiatric systemic lupus erythematosus was the most significant correlate from our meta-analysis for psychological symptoms including anxiety and peripheral nerve features of autonomic disorder and plexopathy. The main abnormal brain magnetic resonance imaging correlates included cerebrovascular disease and demyelination. Brain magnetic resonance imaging correlates poorly with neuropsychiatric systemic lupus erythematosus features, and specific clinical symptoms should be the main determinants of performing magnetic resonance imaging rather than presence of neuropsychiatric systemic lupus erythematosus per se
Metal-insulator transition induced by 16O -18O oxygen isotope exchange in colossal negative magnetoresistance manganites
The effect of 16O-18O isotope exchange on the electric resistivity was
studied for (La(1-y)Pr(y))0.7Ca0.3MnO3 ceramic samples. Depending on y, this
mixed perovskite exhibited different types of low-temperature behavior ranging
from ferromagnetic metal (FM) to charge ordered (CO) antiferromagnetic
insulator. It was found that at y=0.75, the substitution of 16O by 18O results
in the reversible transition from a FM to a CO insulator at zero magnetic
field. The applied magnetic field (H >= 2 T) transformed the sample with 18O
again to the metallic state and caused the increase in the FM transition
temperature Tc of the 16O sample. As a result, the isotope shift of Tc at H = 2
T was as high as 63 K. Such unique sensitivity of the system to oxygen isotope
exchange, giving rise even to the metal-insulator transition, is discussed in
terms of the isotope dependence of the effective electron bandwidth which
shifts the balance between the CO and FM phases.Comment: 5 pages (RevTeX), 2 eps figures included, to appear in J. Appl. Phys.
83, (1998
Black Hole Entropy from Spin One Punctures
Recent suggestion, that the emission of a quantum of energy corresponding to
the asymptotic value of quasinormal modes of a Schwarzschild black hole should
be associated with the loss of spin one punctures from the black hole horizon,
fixes the Immirzi parameter to a definite value. We show that saturating the
horizon with spin one punctures reproduces the earlier formula for the black
hole entropy, including the correction with definite coefficient (-
3/2) for large area.Comment: 4 pages. RevTe
Phase diagram and isotope effect in (PrEu)_0.7Ca_0.3CoO_3 cobaltites exhibiting spin-state transitions
We present the study of magnetization, thermal expansion, specific heat,
resistivity, and a.c. susceptibility of
(PrEu)CaCoO cobaltites. The measurements were
performed on ceramic samples with and . Based on these
results, we construct the phase diagram, including magnetic and spin-state
transitions. The transition from the low- to intermediate-spin state is
observed for the samples with , whereas for a lower Eu-doping level,
there are no spin-state transitions, but a crossover between the ferromagnetic
and paramagnetic states occurs. The effect of oxygen isotope substitution along
with Eu doping on the magnetic/spin state is discussed. The oxygen-isotope
substitution (O by O) is found to shift both the magnetic and
spin-state phase boundaries to lower Eu concentrations. The isotope effect on
the spin-state transition temperature () is rather strong, but it is
much weaker for the transition to a ferromagnetic state (). The
ferromagnetic ordering in the low-Eu doped samples is shown to be promoted by
the Co ions, which favor the formation of the intermediate-spin state of
neighboring Co ions.Comment: 13 pages, including 11 figures, to be published in Phys. Rev.
Entanglement Entropy of 3-d Conformal Gauge Theories with Many Flavors
Three-dimensional conformal field theories (CFTs) of deconfined gauge fields
coupled to gapless flavors of fermionic and bosonic matter describe quantum
critical points of condensed matter systems in two spatial dimensions. An
important characteristic of these CFTs is the finite part of the entanglement
entropy across a circle. The negative of this quantity is equal to the finite
part of the free energy of the Euclidean CFT on the three-sphere, and it has
been proposed to satisfy the so called F-theorem, which states that it
decreases under RG flow and is stationary at RG fixed points. We calculate the
three-sphere free energy of non-supersymmetric gauge theory with a large number
N_F of bosonic and/or fermionic flavors to the first subleading order in 1/N_F.
We also calculate the exact free energies of the analogous chiral and
non-chiral {\cal N} = 2 supersymmetric theories using localization, and find
agreement with the 1/N_F expansion. We analyze some RG flows of supersymmetric
theories, providing further evidence for the F-theorem.Comment: 31 pages, 2 figures; v2 refs added, minor change
Algebraic charge liquids
High temperature superconductivity emerges in the cuprate compounds upon
changing the electron density of an insulator in which the electron spins are
antiferromagnetically ordered. A key characteristic of the superconductor is
that electrons can be extracted from them at zero energy only if their momenta
take one of four specific values (the `nodal points'). A central enigma has
been the evolution of the zero energy electrons in the metallic state between
the antiferromagnet and the superconductor, and recent experiments yield
apparently contradictory results. The oscillation of the resistance in this
metal as a function of magnetic field indicate that the zero energy electrons
carry momenta which lie on elliptical `Fermi pockets', while ejection of
electrons by high intensity light indicates that the zero energy electrons have
momenta only along arc-like regions. We present a theory of new states of
matter, which we call `algebraic charge liquids', which arise naturally between
the antiferromagnet and the superconductor, and reconcile these observations.
Our theory also explains a puzzling dependence of the density of
superconducting electrons on the total electron density, and makes a number of
unique predictions for future experiments.Comment: 6+8 pages, 2 figures; (v2) Rewritten for broader accessibility; (v3)
corrected numerical error in Eq. (5
Black Hole Entropy and Superconformal Field Theories on Brane-Antibrane Systems
We obtain the enropy of Schwarzschild and charged black holes in D>4 from
superconformal gases that live on p=10-D dimensional brane-antibrane systems
wrapped on T^p. The preperties of the strongly coupled superconformal theories
such as the appearance of hidden dimensions (for p=1,4) and fractional strings
(for p=5) are crucial for our results. In all cases, the Schwarzschild radius
is given by the transverse fluctuations of the branes and antibranes due to the
finite temperature. We show that our results can be generalized to multicharged
black holes.Comment: 24 pages in phyzzx.te
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